Amitriptyline can be used to effectively treat a number of conditions such as Depression, neve pain, migraine prevention and other types of persistent pain and can also be used as a sleeping pill to help treat individuals suffering from Insomnia.

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What is Amitriptyline10mg & 25mg used to treat?

Amitriptyline 10mg is the most widely prescribed dosage of this medication. It is used to treat a number of conditions ranging from Mental illnesses such as depression, anxiety, ADHD and Bipolar. Amitriptyline is also used as a treatment for neuropathic pain and other persistent pain conditions such as nerve and back pain. Amitriptyline is also use to treat individuals with Insomnia and can be used as a type of sleeping pill. Amitriptyline has been shown to improve the quality of sleep mostly in individuals who lose sleep as a result of anxiety and depression.

Amitriptyline 10mg is available as a prescription drug only, meaning that it cannot be bought over the counter in supermarkets or other high street chemists. Amitriptyline medication comes in tablet form and should be taken orally, the dosage of amitriptyline that you will be prescribed will depend on the condition that you are currently suffering from. For example Amitriptyline for depression will be a different dosage when using amitriptyline for sleep quality and improvement.

Medicine Direct are licensed to sell Amitriptyline throughout the UK, should you wish to purchase this medication you will need to complete our online health check so that we can learn a little bit more about your condition and prescribe you with the correct dosage of Amitriptyline.

Amitriptyline for Nerve Pain

Amitriptyline belongs to a group of medicines called Tricyclic Antidepressants, although this medication is primarily used to treat mental disorders, it can in smaller dosages be used to treat long term chronic pain such as nerve pain.

Amitriptyline 10mg is a very effective medication for neuropathic pain disorders and can effectively treat other chronic pain, especially if there is a neuropathic element to it. Medications such as Amitriptyline appear to work in the central nervous system by reducing the nerves ability to re-absorb neural transmitter chemicals called Noradrenaline and serotonin. When our body feels pain, the neural transmitter chemicals will send a message to our brain to tell it that we are in pain. If those chemicals are no longer being absorbed by the nerve, they are unable to pass the message to our brain telling it that we feel pain. As a result, the pain is suppressed.

There are many different types of anti-depressants such as amitriptyline that are very effective when treating painful conditons. The general dosage of amitriptyline for nerve pain is 10mg, much lower than what it would be to treat individuals with depression and anxiety.

Amitriptyline for Depression

Amitriptyline 25mg is a medication that is primarily used to treat a number of mental illnesses such as depression and anxiety. Although it’s main use is to treat individuals suffering with mental illnesses it is also very effective when treating other conditions that are related to them such as insomnia and sleep disorders that occur as a result of depression and anxiety. Amitriptyline 25mg is effective when treating depression and anxiety and works by targeting the chemical imbalances in our brain, common among people suffering from mental illnesses. When Amitriptyline corrects the brains chemical imbalance, as a result this will lead to a feeling of calmness and help relieve anxiety and tension, which can also improve quality of sleep.

Using Amitriptyline for Sleep Disorders

Amitriptyline can help individuals in many different ways, one way in which it helps is to relieve tension and anxiety and can help people feel more relaxed. One of the biggest contributing factors to a lack of sleep/insomnia is due to anxiety, depression and stress, Amitriptyline helps to supress the effects of depression and other mental illnesses and allows an individual to feel more relaxed.

Although Amitriptyline has a primary use as an anti-depressant, it has also been shown to be highly effective for treating insomnia and sleeping disorders, especially in individuals who are losing sleep as a result of depression, stress and anxiety. Amitriptyline can be used for sleep disorders as it helps to relax individuals, which in effect can help improve the quality of your sleep.

Amitriptyline Dosage

Depending on the condition that you are using Amitriptyline for, the dosage of this medication will vary. It is important that you provide as much information regarding your condition to our online doctor so they are able to determine which dosage of Amitriptyline you should be taking to treat your condition and symptoms. 

Amitriptyline Dosage


Recommended Daily Dose

Amitriptyline 25mg Depression 1 x 25mg Tablet 3 times daily
Amitriptyline 25mg Anxiety 1 x 25mg Tablet 3 times daily
Amitriptyline 10mg Neuropathic Pain 1 x 10mg Tablet daily
Amitriptyline 10mg Migraine Relief 1 x 10mg Tablet daily

Can I take Amitriptyline and Alcohol?

As with most medicines, if you are consuming alcohol whilst you are currently taking a course of medicines this can prevent the medicine from working to its full ability. Drinking alcohol whilst taking Amitriptyline can prevent the medication from having the desired effect, it can also mean that you may experience many more of the side effects associated to amitriptyline.

We recommend not consuming alcohol when you first start to take the medication so you can see how the Amitriptyline affects your body and if you suffer from any of the side effects.

Amitriptyline Side Effects

Like all medications, Amitriptyline can result in a number of side effects that can affect individuals in different ways. Some side effects are a lot more common than other side effects, however we want to make you aware of all the potential side effects that you may or may not experience whilst taking amitriptyline.

The most common amitriptyline side effects are:
  • Dizziness
  • Dry mouth
  • Sickness
  • Headaches
  • Tiredness
  • Constipation
  • Weight gain
Serious Amitriptyline side effects include:
  • Persistent Heartburn
  • Shaking
  • Muscle spasms
  • Severe stomach ache
  • Fainting
  • Changes in vision (blurred)
  • Trouble breathing

We recommend that you should tell your doctor of all side effects that you are experiencing as a result of taking amitriptyline. We would also recommend stopping your course of amitriptyline immediately if you experience any of the more serious side effects.

Amitriptyline Precautions and Warnings

Worsening of depression

If you are suffering from depression, Amitriptyline can make this worse before it gets better. There may be an increase in suicidal thoughts in young adults. Your doctor and members of your family should be informed so they can watch your behaviour closely and look for signs that your behaviour/mental state may be changing.

Withdrawal Symptoms

If you have been taking this medication for a long time, your dosage and frequency should be gradually reduced. Stopping your course of medicine suddenly may cause side effects such as sickness, tiredness and headaches. Do not stop taking this medication without talking to your doctor, you should complete your course of tablets.

Amitriptyline during pregnancy

During pregnancy, this medication should be used only when needed. This medication will pass into the breastmilk and the effect of this medication on an infant is unknown.

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