Livial (Tibolone) 2.5mg

  • Contains Tibolone as the active ingredient
  • Hormone Replacement Therapy (HRT)
  • Relieves symptoms of the menopause
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From As low as £49.99

Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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What is Livial (tibolone)?

Livial is a form of hormone replacement therapy (HRT) for postmenopausal women. It contains the active ingredient tibolone, which works on different tissues in the body to emulate the sex hormones oestrogen, progesterone and testosterone. This relieves menopausal symptoms and allows women to carry on with their everyday lives.

Livial is the branded version of Tibolone.

How can I buy Livial (Tibolone) online safely?

This medicine is only available on prescription, and you will only be prescribed Livial tablets if your symptoms are hindering your everyday life. You can buy Livial online from Medicine Direct after an online consultation with one of our registered health professionals. They will give you a prescription for this hormone replacement therapy (HRT) medication if they deem it the most appropriate for you to take.

From there, you can order Livial from our online pharmacy; order by 2pm and we can offer you next day delivery.

To safely buy medicine online, only order it from a registered pharmacy that is regulated by the General Pharmaceutical Council (GPhC), like Medicine Direct.

What are the benefits of Livial (Tibolone)?

Livial tablets are an effective HRT treatment for relieving women's menopausal symptoms, including osteoporosis.

These tablets contain the active ingredient tibolone, which has positive effects on various areas of your body including the brain, vagina and bones. Tibolone breaks down in the body and emulates the sex hormones oestrogen, progesterone and testosterone. This makes it different from most other HRT treatments as most other forms of hormone replacement therapy contain actual sex hormones.

Livial also increases the testosterone levels in a woman's body, which helps to limit some of the side effects that are commonly associated with HRT.

What is the menopause?

The menopause is a condition that affects all women, usually occurring between the ages of 45 and 55. As women get to this age, their ovaries progressively start to produce less oestrogen, which will stop them from having monthly periods. However, the change in hormone levels can cause symptoms that may hinder your daily life.

This may manifest in physical symptoms including:

  • Night sweats
  • Osteoprorosis
  • Vaginal dryness
  • Dryness of the eyes
  • Spontaneous hot flushes that cause sweating, blushing a stronger heartbeat than usual

Aside from physical symptoms, the menopause can also cause psychological effects, including insomnia, depression and mood swings.

Women will normally experience symptoms for around four years, although it is important to bear in mind that menopausal symptoms affect different women in different ways. Some may get by with very few symptoms at all, while some may suffer from persistent and severe symptoms.

Other alternatives

There are various different hormone replacement therapy treatments available for postmenopausal women. HRT patches are also available to try instead of tablets.

Alternatives to Livial tablets include the likes of Estradot, Elleste, Evorel and Kliofem. These medicines and others are available to order from Medicine Direct after an online consultation with a doctor. Just complete an online consultation and they will discuss treatment options with you.

Who can take Tibolone?

Livial may not be suitable for everyone to take.

Do not take Livial if any of the below applies to you:

  • You have any blood clotting disorders
  • You are allergic to tibolone or any other ingredient contained in this medicine (please refer to the Ingredients tab for a full list)
  • You have, have ever had, or are suspected of having breast cancer
  • You have any unexplained vaginal bleeding
  • You have (or are suspected of having) a form of cancer that is sensitive to oestrogens, such as cancer of the womb lining
  • You have or have had a liver disease and your liver function tests have not returned to normal
  • You have excessive thickening of the womb lining that has not been treated
  • You suffer from the inherited blood disorder porphyria
  • You have or have recently had a disease that was caused by blood clots in the arteries, such as a stroke, heart attack or angina

Speak to your doctor before taking Livial if you have ever had any of the following

  • Gallstones
  • Fibroids in the womb
  • Endometriosis (growth of the womb lining outside the womb), or a history of growth of the womb lining outside the womb
  • Epilepsy
  • A liver disorder, such as a benign liver tumour
  • Diabetes
  • An increased risk of developing blood clots
  • High blood pressure
  • Migraine or severe headaches
  • An increased risk of oestrogen-sensitive cancer (for example, having a mother or sister who has suffered from this problem)
  • Systemic lupus erythematosus
  • Asthma
  • Otosclerosis
  • Fluid retention from cardiac or kidney problems
  • High levels of fat in the blood

Possible side effects

Like all medicines, Livial can cause side effects, although not everyone who takes it will get them.

Common side effects can include:

  • Stomach or pelvic pain
  • Unusual hair growth
  • Breast pain
  • Weight gain
  • Vaginal problems, such as thrush, itching and irritation
  • Thickening of the womb lining or lining of the cervix
  • Vaginal bleeding or spotting

Uncommon side effects may include:

  • Acne
  • Stomach upset
  • Swelling in the hands, feet or ankles (fluid retention)
  • Vaginal infection
  • Uncomfortable breasts or nipple pain

Please note, this list is not exhaustive. Please refer to the Side Effects tab for a list of more serious reactions you may suffer.

Livial (Tobolone) Dosage and Directions

How do I take Livial?

Our pharmacists and prescribers follow NICE guidelines when prescribing Livial

Always take Livial exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly and speak to your doctor or pharmacist for further guidance if you are still not sure.

Unless you have been instructed to take this medicine differently, the usual recommended dose is one tablet each day. Take the tablet at the same time every day.

Swallow Livial tablets whole with a drink of water. Do not crush or chew them.


If it has not yet been 12 months since your final period, you should not take this HRT medicine.

Taking it sooner than 12 months after your last natural period may result in irregular bleeding.

If you are swapping over from using another form of HRT where you had periods, wait until your next period ends until you start taking Livial.

What if I forget to take it?

If you are less than 12 hours late in taking Livial, take it as soon as you remember. If you are more than 12 hours late, just skip the dose you missed and take the next tablet at your usual time.

Do not take a double dose to try and make up for missing a previous one.

What if I take more than I am supposed to?

Taking an extra dose of Livial is unlikely to do you any harm, although you may feel sick, vomit or have vaginal bleeding.

Speak to your doctor if you become worried or have taken more than one extra dose.

If you need to have an operation

Tell your doctor if you are taking Livial if you need to have surgery. You may need to stop taking this medicine around 4 to 6 weeks before you have the operation; this will reduce the risk of blood clots.

Is it safe to buy Livial online?

It is completely safe to purchase Livial online when you order from Medicine Direct. We are a fully registered UK pharmacy that is regulated by the General Pharmaceutical Council (GPhC). All of our medical professionals are registered with the General Pharmaceutical Council, General Medical Council (GMC) and the MHRA.

How do I order Livial online?

Livial is only available to order when you have a prescription from a doctor. You can order it from Medicine Direct following a simple and confidential online consultation with one of our registered health professionals.

Are Livial tablets available for next-day delivery?

If you place your order by 2pm, next day delivery is available.

How much Livial can I get in one purchase?

You can only order up to a maximum of six months' worth of Livial at one time. This is because it is a prescription-only medication.

What does the price include?

The price includes an online consultation with a registered health professional, the medicine itself and delivery.

What are the advantages of buying Livial online?

Ordering Livial online means that you can have your condition reviewed and prescribed on the very same day; you don't need to wait days or even weeks to get an appointment with your local GP. All of our doctors, pharmacists and prescribers are fully qualified and registered, meaning they can prescribe medicine just like your local doctor. Simply complete our online consultation and you will be prescribed a suitable medicine.

Livial (Tibolone) Side Effects

Information on more common side effects can be found on the main product page.

A rare side effect of Livial can include itchy skin.

Some women who use this medicine have also reported:

  • Skin problems like a rash or itching
  • Depression, dizziness and headaches
  • Joint or muscle pain
  • Blurred vision or loss of vision
  • Changes in liver tests

Speak to your doctor if you suffer from any of the reactions listed above.

Serious allergic reaction

In very rare cases, it is possible that you may suffer a serious allergic reaction to Livial.

Call 999 or go to A&E straight away if you have any of the following:

  • You are wheezing
  • You develop a skin rash that may include red, itchy, swollen, blistered or peeling skin
  • You are finding it difficult to breathe or speak
  • You have tightness in your chest or throat
  • You have swelling in your face, mouth, tongue, lips or throat

You may be having a serious allergic reaction and require treatment in hospital immediately.

Always read the patient information leaflet for comprehensive details on side effects. If you are worried about side effects, please speak to your doctor.

Livial (Tibolone) Warnings

Some medicines may interfere with how Livial works. Always tell your doctor if you are currently taking (or have recently taken) any other prescription or non-prescription medication, herbal remedies, vitamins or supplements.

In particular, tell them if you are taking any of the following:

  • Medicines for blood clotting, such as warfarin
  • Medicines containing the herbal remedy St. John's wort
  • Medicines for epilepsy
  • Medicines for tuberculosis

Find out more information on medicines that interact with Livial

What precautions should I take when using Tibolone?

Livial contains lactose; if your doctor has told you that you are allergic to certain types of sugar, do not take this medicine without speaking to them.

Do not take this medicine if you have galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.

The following conditions are more frequently reported in women who use HRT compared to those who are not:

  • Stroke
  • Ovarian cancer
  • Heart disease
  • Abnormal growth of the womb lining or cancer of the womb lining
  • Blood clots in the veins of the legs or lungs
  • Likely memory loss if hormone replacement therapy begins over the age of 65
  • Breast cancer

Stop taking Livial and speak to a doctor immediately if:

  • You become pregnant
  • You get any of the conditions listed in the 'Who can take Livial?' section
  • There is a large rise in your blood pressure
  • You have yellowing of your skin or the whites of the eyes
  • You notice any signs of a blood clot (sudden chest pain, breathing difficulties, painful swelling or redness of the legs)
  • You get migraine-like headaches which have not happened before

Driving and using machines

Livial should not directly impair your ability to drive or operate machinery.

However, if you suffer from dizziness or vision problems, you should not drive, ride a bike or operate any machines until you feel better again. If these side effects persist, speak to your doctor.

Always read the patient information leaflet for comprehensive information on warnings and drug interactions. If you have any questions or concerns, please speak to your doctor or pharmacist before you start your course of HRT.

Pregnancy and breastfeeding

Livial should only be taken by postmenopausal women, it should not be taken by women who are pregnant. Stop taking Livial and to your doctor if you become pregnant.

Talk to your doctor or pharmacist before taking Livial tablets if:

  • You are currently pregnant or breastfeeding
  • You think you might be pregnant
  • You are trying to get pregnant

Livial (Tibolone) Ingredients

Livial contains tibolone as its active ingredient.

The inactive ingredients also contained are: potato starch, lactose monohydrate, ascorbyl palmitate and magnesium stearate.

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written bySonia Khan MPharm: 2076091

Updated on: 03/06/2021

This content has been written by our Pharmacist Sonia Khan and has been medically reviewed by our Superintendent Pharmacist Hussain Abdeh

Sonia Khan
MPharm: 2076091


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