• Prescribed to treat High Blood Pressure (Hypertension)
  • Thiazide Diuretics, more commonly known as "water pills"
  • Treats the build up of fluid within blood vessels, effectively lowering blood pressure

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High Blood Pressure Key Facts UK

  • High blood pressure is responsible for more than half of all stroke and heart attacks in the UK
  • 1 in 3 adults in the UK has high blood pressure (31% men and 26% women)
  • High blood pressure rarely has symptoms and is called the 'Silent Killer'
  • High blood pressure costs the NHS over £2.1 billion every year
  • 75,000 people died of High Blood Pressure in 2015

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What are Bendroflumethiazide tablets?

Bendroflumethiazide is a medication that belongs to a class of drugs known as thiazide diuretics, more commonly referred to as 'water pills'. They are called water pills because they make you urinate more often.

Diuretics are medicines that promote and increase the excretion of urine.

It is a prescription-only medicine that is designed to treat the build-up of fluid in your body, including the fluid in your blood vessels, which can help to lower high blood pressure.

Bendroflumethiazide tablets are primarily prescribed to treat high blood pressure and the build-up of fluids in the body (Oedema).

You can buy Bendroflumethiazide from Medicine Direct, following an online consultation with one of our certified doctors. We sell this medicine in packets of either 28, 56, or 84 tablets, in doses of either 2.5mg or 5mg.

What is Bendroflumethiazide used to treat?

Bendroflumethiazide is commonly used to treat high blood pressure (hypertension).

High blood pressure is caused by a wide range of issues, including a family history of high blood pressure, smoking, obesity, age, lack of exercise and high levels of salt in your diet.

Certain health problems are also linked to it, including kidney disease and diabetes.

How does Bendroflumethiazide treat high blood pressure?

Thiazide Diuretics like Bendroflumethiazide tend to work directly on the kidneys and causes them to pass out more fluid. Thiazide Diuretics inhibit sodium absorption and as a result increases fluid loss in the urine, a process called diuresis.

Taking water tablets like Bendroflumethiazide make you need to urinate more often, which helps to get rid of excess fluid in your body. This also means that you will have less fluid in your blood vessels and body tissues, which helps to lower your blood pressure.

Thiazide Diuretics also have a dilating (widening) effect on the blood vessels which allows blood to flow through the circulatory system using less force from the heart. 

How to take Bendroflumethiazide

You will normally be instructed to take Bendroflumethiazide once a day, in the morning.

If your doctor prescribes Bendroflumethiazide to be taken twice a day, you should take it once in the morning and again around midday.

To ensure this medicine's effectiveness, try to make sure you are taking Bendroflumethiazide at the same time(s) every day.

Do not take thiazide diuretics after 4pm or in the evening; this medicine will make you need to go to the toilet, which will require you to wake up in the middle of the night.

Bendroflumethiazide tablets should be swallowed whole with a drink of water.

It can be taken with or without food.

Bendroflumethiazide dose

The dose of Bendroflumethiazide you are prescribed will be heavily dependent on your condition, diagnosis, and the severity of your blood pressure.

Typically, the initial starting dose for Bendroflumethiazide is:



Oedema 5mg - 10mg once daily in the morning or on alternative days
Hypertension 2.5mg once daily in the morning
Source NICE

Who can take Bendroflumethiazide?

Make sure you inform your doctor before you start taking Bendroflumethiazide if you have any of the following conditions:

  • You have diabetes
  • You are allergic to Bendroflumethiazide or any of the other ingredients in this medicine (please, refer to the ingredients tab for a full list)
  • You have diabetes
  • You have liver or kidney problems
  • You have the rare blood disease porphyria
  • You have lupus (an inflammatory condition)
  • You have underactive adrenal glands (Addison's disease)
  • You have difficulties urinating
  • You have vomiting or diarrhoea
  • You have had an allergic reaction to Bendroflumethiazide or any other medicines in the past
  • You have high levels of uric acid or calcium in your blood
  • You have high levels of magnesium, sodium, or potassium in your blood
  • You have liver disease caused by alcohol

Bendroflumethiazide side effects

Like all medications, Bendroflumethiazide does come with the risk of certain side effects, although not everyone who uses it will get them.

The lower your dose, the less likely you are to experience any adverse effects. Side effects often ease as you continue taking the tablets and your body gets used to them.

Common side effects of this medication include:

  • Feeling dizzy
  • Severe joint pain
  • Feeling faint
  • Feeling thirst with a dry mouth
  • Stomach pain
  • Loss of appetite
  • Diarrhoea
  • Constipation
  • Unexpected weight loss
  • Bladder or skin infection
  • Thrush
  • Blurred vision
  • Increased thirst

Speak to your doctor if any of the above symptoms bother you or do not go away.

Please note, this list is not exhaustive. For a list of rarer and more serious adverse reactions you may have to Bendroflumethiazide, please refer to the Side Effects tab on this page.

Are there any Bendroflumethiazide alternatives?

There are many different types of Thiazide Diuretics that are available. If you are wanting to change to another treatment option similar to Bendroflumethiazide, please visit your own doctor as you will need to be physically assessed before being prescribed a different treatment.

We are unable to prescribe an alternative to Bendroflumethiazide if your own doctor has not yet prescribed this for you.

How long do Bendroflumethiazide tablets take to work?

Bendroflumethiazide usually takes around 2 hours to start working. However, it may take between 3-6 hours before fluid is excreted from your body.

Can I buy Bendroflumethiazide online in the UK?

Yes, you can buy Bendroflumethiazide 2mg and 5mg tablets online from most UK pharmacies. Bendroflumethiazide is a prescription only medicine, so you will need to complete an online health consultation with a doctor or healthcare professional, this is so they are able to assess your condition and ensure that Bendroflumethiazide 2.5mg or 5mg tablets are the most suitable treatment option for your condition.

It is important to ensure that you are buying medicine online from a UK fully regulated pharmacy. To learn more about our company, team, medical professionals, and the licenses we hold, visit our about us page.


Bendroflumethiazide Dosage

Always take Bendroflumethiazide exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly before you start to use it. Speak to your doctor or pharmacist for advice if you are not sure how to take it.

The dose of Bendroflumethiazide tablets you are required to take will depend on whether you are being treated for high blood pressure or a different condition.

All of our Doctor and Pharmacists follow NICE guidelines when prescribing Bendroflumetiazide.

What if I take more than I am supposed to?

Taking too much of this medicine can results in a weak or fast heartbeat, fits (seizures), dizziness and/or confusion. These are all signs of dehydration. An overdose may also result in low blood pressure.

The amount of Bendroflumethiazide that constitutes an overdose will vary from person to person.

If you take too much Bendroflumethiazide or feel unwell, you should go to A&E straight away.

Do not drive yourself; you must either call an ambulance or ask someone else to drive you to hospital. Be sure to take your medicine packet or leaflet with you.

What if I forget to take it?

If you accidentally forget to take this medicine, just take it as soon as you remember, as long as it is before 4pm. If it is later than 4pm, you should skip the dose you forgot to take and continue taking Bendroflumethiazide at the usual time the next day.

Never double dose in an attempt to make up for missing a previous one.

For this medication to restore your normal blood pressure level, it is important to be consistent with your doses of Bendroflumethiazide. For this reason, you should try to take it at the same time each day, to get into a routine of taking it. Some people find it beneficial to set an alarm at the time they are supposed to take it, as a reminder. Speak to your doctor or pharmacist about other ways you can remember to take your medication.

Bendroflumethiazide FAQ's

What is bendroflumethiazide used to treat?

Bendroflumethiazide is a thiazide diuretic which treats high blood pressure (hypertension) by removing excess fluid from your body.

How long does bendroflumethiazide take to work?

Bendroflumethiazide will begin to work within 2 hours of taking it, however you will not notice a reduction in your blood pressure until 3 or 4 days into your course.

How long will I need to take Bendroflumethiazide for?

High blood pressure requires a long term treatment plan. It is likely that you will need to take high blood pressure medicine for many years.

Is Bendroflumethiazide safe to take for a long time?

Yes, bendroflumethiazide is intended for long term use. Taking this medicine for a long time does not cause any long lasting side effects.

What happens if I stop taking it?

You should not stop taking your medicine without talking to your doctor first. Stopping taking your medicine can result in your blood pressure increasing. This is a long term treatment plan and should be taken exactly as prescribed.

Is bendroflumethiazide a type of beta-blocker?

No, bendroflumethiazide is a Thiazide Diuretic which prevents water retention in the body. Beta blockers control the rate at which the heart beats. Both can be used to treat high blood pressure, however both work in different ways.

When should I take my tablets?

Do not take Bendroflumethiazide after 4pm, as this will make you need the toilet during the night. It is best to take your prescribed dose at the same time every day.

Can I drink alcohol whilst taking Bendroflumethiazide?

Drinking alcohol whilst taking Bendroflumethiazide can increase the blood pressure lowering effects and cause you to get light headed or dizzy. Alcohol can also directly increase your blood pressure. When drinking alcohol, it is best to do so in moderation.

What is the price of Bendroflumethiazide in the UK?

Prices start at £12.99 for 28 tablets.

Bendroflumethiazide Side Effects

A list of common adverse reactions can be found on the main product page.

More serious side effects of taking Bendroflumethiazide can be found below. You should seek medical attention if you suffer from any of the below side effects:

  • You have sudden or severe stomach pain – this could be a sign of pancreas problems
  • You have unexplained bruising or bleeding – this could be a sign of blood problems
  • You have strong-smelling and dark yellow urine, you are constantly thirsty, feeling dizzy/light-headed, are urinating less than 4 times a day – these could be signs that you are dehydrated
  • You have yellowing of the skin or whites of the eyes, itching, dark urine or pale stools – these could be signs of a liver problem
  • You have low blood pressure

Serious allergic reaction

In rare instances, you may suffer a serious allergic reaction while using this medication. You may require immediate treatment in hospital if you experience any of the below symptoms; if you do exhibit any of these, you must either go to A&E or call 999 straight away:

  • You have tightness in the chest or throat
  • You are wheezing
  • You have a skin rash that is red, itchy, swollen, blistered or peeling skin
  • You are finding it difficult to breathe or speak
  • You have swelling in your tongue, throat, lips, mouth or face

The above lists may not be exhaustive; always read the patient information leaflet thoroughly for a comprehensive list of possible Bendroflumethiazide side effects.

If you have any questions or concerns, please do not hesitate to speak to your doctor before you start to take Bendroflumethiazide.

Bendroflumethiazide Warnings and drug interactions

Bendroflumethiazide tablets may interact with other medications, which can hinder its effectiveness. Thiazide diuretics can also increase the risk of developing Gout.

Before you start to take a new medicine, you should always tell your doctor if you are already taking any others. This includes both prescription and non-prescription medicines, herbal remedies, vitamins and supplements.

In particular, make sure you tell your doctor if you are currently taking, or have recently taken, any of the following:

  • Any nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen, ibuprofen, indometacin or ketorolac
  • Toremifene (used to treat certain types of cancer)
  • Any vitamin D preparations
  • Carbenoxolone (used to treat stomach ulcers)
  • Digoxin (used to treat heart problems)
  • Cisplatin (a cancer treatment)
  • You are receiving adrenocorticotropic (ACTH) hormone
  • Moxisylyte (for Raynaud’s syndrome)
  • Any calcium channel blockers (used to lower blood pressure)
  • Pimozide or thioridazine (for mental illnesses)
  • Corticosteroids (to reduce inflammation)
  • Antihypertensive agents (used to treat high blood pressure)
  • Prazosin (for Raynaud's syndrome, high blood pressure, an enlarged prostate and heart failure)
  • Reboxetine, tricyclic antidepressants
  • Sympathomimetics (for asthma, heart medicines or as a decongestant)
  • Allopurinol (used for gout)
  • Theophylline (to treat breathing problems like asthma)
  • Medicines to control an irregular heartbeat: disopyramide, amiodarone, flecainide, quinidine, lidocaine or mexiletine
  • Oestrogen or combined oral contraceptives
  • Terfenadine (for allergic reactions)
  • Any opioids, such as morphine
  • Any barbiturates
  • The muscle relaxants baclofen, tizanidine, tubocurarine, gallamine, alcuronium or pancuronium
  • Any beta-agonists
  • Acetazolamide (for epileptic seizures and glaucoma)
  • Lithium (for certain mental health problems)
  • Calcium salts
  • Colestipol & cholestyramine (for lowering cholesterol)
  • Any sulfonylureas (to control blood sugar levels)

The above list is not exhaustive, learn more about Bendroflumethiazide drug interactions.

Bendroflumethiazide and alcohol

You are advised to not drink alcohol while taking this medication. Alcohol may cause dizziness when you stand up, which is due to low blood pressure.

Driving and operating machinery

Bendroflumethiazide will not directly impair your ability to drive or operate machinery. However, dizziness is a side effect associated with this medicine; so if you experience dizziness while taking Bendroflumethiazide, you should not drive, ride a bike, or operate machinery until you feel better.

Pregnancy and breastfeeding

Bendroflumethiazide is not recommended for women who are pregnant, although your doctor may prescribe you this medication if they believe the pros of taking it outweigh the risks.

Before taking Bendroflumethiazide, you should tell your doctor if you are either currently pregnant, think you might be pregnant, or are trying to get pregnant.

It is also not recommended for women who are breastfeeding, as it can reduce the amount of breast milk a woman produces. Tell your doctor if you are breastfeeding, as they can discuss the risks and possible alternatives you can use.

For more information on high blood pressure and pregnancy. 

Bendroflumethiazide Ingredients

The main active ingredient within this medicine is: Bendroflumethiazide

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

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Written byHussain Abdeh MPharm: 2211840

Published on: 12/10/2020

Updated on: 24/06/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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