Colgate Duraphat

  • High fluoride treatment
  • Prevents tooth decay
  • Prescription Only toothpaste
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From As low as £14.99

Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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What is Colgate Duraphat?

Colgate Duraphat 5000 is a high fluoride toothpaste that is often prescribed for people over the age of 16 who are at a higher risk of suffering from tooth decay.

It contains around four times the normal level of sodium fluoride in the strongest regular toothpaste and works to provide the highest level of protection against decay and cavities.

You need a prescription to buy Colgate Duraphat 5000 toothpaste. 

What is Colgate Duraphat used to treat?

Colgate Duraphat toothpaste is used to help prevent and reverse the early stages of tooth decay.

It contains more than three times the amount of fluoride a normal toothpaste contains. Clinical studies have shown that a high fluoride toothpaste like Colgate Duraphat can prevent tooth decay and even reverse the early stages of decay, making for healthier teeth and improved oral health.

Your dentist or health professional will have diagnosed you with an increased risk of tooth decay in order for you to purchase this product.

How does Colgate Duraphat work?

Colgate Duraphat contains sodium fluoride in higher doses than regular toothpastes. When you brush your teeth with this high fluoride toothpaste, it will be applied to the teeth and prevent the breakdown of the tooth surface, which encourages remineralisation and helps to make damaged teeth stronger. It will strengthen the enamel of the teeth and make them more resistant to plaque acids, which cause tooth decay.

How to use Colgate Duraphat

  1. Use Colgate Duraphat three times a day, after meals.
  2. Apply 2cm of the toothpaste to your toothbrush.
  3. Brush your teeth for 3 minutes, brushing vertically down from the gum to the end of each tooth.
  4. After brushing, do not rinse your mouth with water. Spit the foam from your mouth, taking care not to swallow it.

It is best not to drink or eat anything for at least 30 minutes after brushing your teeth. This will give the toothpaste time to get to work on your teeth.

Read the information that comes with your toothpaste before you start to use it.

Who can use Colgate Duraphat?

Colgate Duraphat toothpaste is suitable for adults and children who are aged 16 and over.

It is not suitable for children under 16 years old.

It is generally prescribed for people who have any of the following:

  • Active tooth decay or a history of tooth decay
  • Exposed root surfaces
  • High-sugar diet
  • Orthodontic appliances
  • Dry mouth

Do not use this toothpaste if you are allergic to fluoride or any of the other ingredients contained within it.

Always read the patient information leaflet before you start to use a new medication.

Can you buy Colgate Duraphat 5000 over the counter?

No, Colgate Duraphat toothpaste must be prescribed for you by a dentist. They will prescribe this toothpaste if you are at an increased risk of tooth decay.

Can you buy Colgate Duraphat 5000 online in the UK?

Yes, you can buy Colgate Duraphat online. Medicine Direct stocks this high fluoride toothpaste and it can be bought after you have completed a confidential online consultation that has been assessed by one of our certified prescribers. All you need to do is answer some questions about your medical history and condition.

We are regulated by the General Pharmaceutical Council (GPhC) and other necessary regulatory authorities in the UK, to ensure we only sell safe and approved medication. For your own safety, only order from regulated pharmacies like Medicine Direct.

Colgate Duraphat alternatives

Using a high fluoride toothpaste like Colgate Duraphat will help to prevent tooth decay, but this is only part of the solution. You can help to keep your teeth healthy by also doing the following:

  • Flossing
  • Visiting the dentist regularly
  • Avoiding sugary drinks and snacks
  • Limiting sweet foods to mealtimes
  • Brushing your teeth each day
  • Using a fluoride mouthwash between brushing

Colgate Duraphat Dose and Directions

Our pharmacists and prescribers follow NICE guidelines when prescribing Colgate Duraphat.

Always follow your dentist or pharmacist's instructions when using fluoride toothpaste. Read the patient information leaflet thoroughly before you use it and check with your dentist or pharmacist if you are not sure how to use it.

Use Colgate Duraphat as a replacement for your normal toothpaste.

Apply 2cm of the toothpaste to your toothbrush and brush your teeth thoroughly three times a day, ideally after each meal.

Spit out the excess foam and avoid drinking or eating for at least 30 minutes after brushing; this will give the fluoride time to work on your teeth. Do not swallow the foam.

What if I forget to use it?

If you forget to brush your teeth with fluoride toothpaste, brush them as soon as you remember.

To successfully prevent tooth decay, it is vital that you brush your teeth at least twice, preferably 3 times each day. This should be done first thing in the morning, after an evening meal and before you go to bed. Do not over-brush your teeth as this can wear down the enamel.

If you have trouble remembering to brush your teeth, some people find it useful to set an alarm as a reminder.

Why can I only get this toothpaste on prescription?


This toothpaste contains approximately four times the amount of fluoride that a regular toothpaste contains, making it suitable only for those who are at an increased risk of tooth decay.

Will it help people with sensitive teeth?


Colgate Duraphat 5000 helps to strengthen the enamel of the teeth, which can help to fight sensitivity.

Will it help with toothache?


Colgate Duraphat helps to significantly reduce the risk of tooth decay and cavities, which can be major causes of toothache.

Should I rinse after I’ve brushed my teeth with Colgate Duraphat?


No, do not rinse your mouth with water after brushing your teeth with this toothpaste. This will wash away the toothpaste and prevent it from working on your teeth. You should spit the foam from your mouth after brushing and avoid eating or drinking for at least 30 minutes.

How long will a tube last?


Colgate recommends that one tube of this toothpaste should last for around one month.

Should I use it every day?


Yes, you should use Colgate Duraphat at least two, preferably three times each day, after meals.

Will Colgate Duraphat whiten my teeth?


Colgate Duraphat helps to keep your teeth clean, but it is not specifically a whitening toothpaste.

Can I drink after brushing my teeth?


You should wait for at least 30 minutes after brushing your teeth before you eat or drink anything

Is it safe to leave this toothpaste on overnight without rinsing?


Yes, you should only spit the foam out of your mouth and not rinse. The fluoride in the toothpaste is soluble and will be eliminated within a few hours.

Can I use mouthwash with this toothpaste?


Yes, using mouthwash will help to provide extra protection against tooth decay. However, you should use it at a different time of day to brushing your teeth.

Colgate Duraphat Side Effects

In very rare cases, it is possible to suffer a serious allergic reaction (anaphylaxis) to this product.

You must either call 999 or go to A&E straight away if you experience any of the following symptoms:

  • You have tightness in your chest or throat
  • You develop a skin rash that is red, itchy, swollen, blistered or peeling
  • You have swelling in your face, throat, lips, mouth or tongue
  • You are finding it difficult to breathe or speak
  • You are wheezing

If you suffer from any of the above reactions, you may require immediate treatment in hospital. Always read the information on the side of the box and information leaflet for a comprehensive list of possible side effects.

Always read the patient information leafet or box directions before use. If you have any questions or concerns at all, we strongly advise you to discuss these with your doctor, dentist or pharmacist before you start using this toothpaste.

Colgate Duraphat Warnings and drug interactions

Before you start to take any new medicines, it is very important that you always inform your doctor of any medication you may already be using. This includes both prescription and non-prescription medicine, herbal remedies, vitamins and supplements.

At present, there are no known medications that interact with Colgate Duraphat toothpaste.

Do not eat or drink anything for at least 30 minutes after brushing your teeth with Colgate Duraphat. This can inhibit the toothpaste's effectiveness.

This medication contains sodium benzoate, which is a mild irritant to the eyes and mucous membrane. If you experience a reaction to this medicine, speak to your doctor or pharmacist for advice.

If you have any questions or concerns at all, we strongly advise you to discuss these with your doctor before you start to use the product.

Pregnancy and breastfeeding

Colgate Duraphat toothpaste is safe to use while pregnant and breastfeeding. Nonetheless, like all medicines, you should inform your doctor or pharmacist before you start using Colgate Duraphat if you are pregnant, think you might be pregnant, are trying to get pregnant, or are breastfeeding.

Colgate Duraphat Ingredients

The active ingredient contained in this toothpaste is sodium fluoride.

Please refer to the patient information leaflet for a comprehensive list of inactive ingredients also contained in this medication.

Speak to your doctor, dentist or pharmacist before using Colgate Duraphat if you have an allergy to any of the ingredients contained in this product.

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Hussain Abdeh MPharm: 2211840

Updated on: 27/09/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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