• Prevents Malaria
  • Treats Malaria
  • Used in high risk destinations
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What is Malarone?

Malarone is one of the latest treatments introduced to prevent malaria. If you are travelling to a destination that is a high risk area for malaria, you should take Malarone tablets before, during and after you come back from your trip.

It is a prescription-only medication. You can buy Malarone tablets online at Medicine Direct. Following an online consultation with a doctor, who will prescribe you these tablets if they deem it a suitable treatment for you, you can order this medication from our online pharmacy. Place your order by 2pm and we can offer you next day delivery on your tablets.

We sell doses ranging from 16 tablets (1 week's worth of medicine), right the way up to 12 months' worth of tablets, depending on how long you intend to travel for.

What is Malarone used to treat?

These tablets are used in the prevention of catching malaria when you travel to a destination that is designated a high-risk area. It is also an effective treatment for malaria if you catch it while abroad.

It is a branded antimalarial medication that contains two active ingredients, atovaquone and proguanil. These ingredients prevent you from developing malaria from mosquito bites, which are very common in tropical countries. Mosquito bites can pass malaria straight into the bloodstream.

Malaria is a tropical disease that is responsible for over a million deaths each year, so travellers should be very aware of the facts and the areas in the world that pose the highest risk of catching it. Malaria is a parasite that multiplies in the body's red blood cells, it is not a virus or bacterial infection.

Malaria in humans is caused by four different species of plasmodium:

  • falciparum
  • malariae
  • ovale
  • vivax

The symptoms of malaria occur in stages, normally in 48 hour cycles. It is a contagious disease that can be spread by both animals and humans. If you suffer from malaria and do not receive proper treatment, you could have recurrences of the disease months later.

However, while malaria is a serious and highly infections disease, it can be cured in a way that kills all the malaria parasites, making for a full recovery. To properly treat malaria, you will need the right medication.

Who can use Malarone?

Malarone is an effective malaria prevention and treatment medicine, but it is not suitable for everyone to take.

Do not take Malarone tablets if you are allergic to atovaquone, proguanil hydrochloride or any of the other ingredients contained in these tablets (see the Ingredients tab for full details).

Do not use Malarone to prevent malaria if you have severe kidney disease.

Speak to your doctor before taking Malarone if any of the following apply to you:

  • You have severe kidney disease
  • Your child weighs less than 11 kg and is being treated for malaria

Always read the patient information leaflet for full details.

Possible side effects

As with all medications, Malarone comes with the risk of possible side effects, although these will not affect everyone who takes it.

Most common side effects are mild and do not last for long.

Common adverse effects of using Malarone include:

  • Stomach pains
  • Feeling sick or being sick
  • Headaches
  • Diarrhoea
  • Dizziness
  • Problems sleeping
  • Loss of appetite
  • Depression
  • Strange dreams
  • Cough
  • Fever
  • A skin rash that may be itchy

Speak to a doctor if any of these effects bother you or do not go away.

If you have a blood test, these reactions may show up in your results:

  • Low levels of sodium in your blood
  • An increase in liver enzymes
  • A reduced number of red blood cells – this can cause headaches, shortness of breath and tiredness
  • A reduced number of white blood cells, making you more vulnerable to infections
  • A decrease in all blood cell types

Please note, these lists are not exhaustive. For rarer and more serious reactions, please refer to the Side Effects tab on this page.

Always read the patient information leaflet for a comprehensive list of adverse effects you may suffer while using Malarone tablets.

Malarone Dosage

Our pharmacists and prescribers follow NICE guidelines when prescribing Malarone

Always take malaria tablets like Malarone exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly before you start to take them. Ask your doctor or pharmacist for advice if you are not sure how to take the tablets.

Whenever possible, take Malarone tablets with food or a milky drink. Doing this will increase the amount of Malarone your body can absorb, which will make the treatment more effective. For the best results, try to take the tablets at the same time every day.

To prevent malaria

As a prevention for malaria, adults are normally instructed to take 1 tablet once a day.

Malarone is not recommended for children or adults who weigh less than 40 kg to prevent malaria.

Start taking Malarone tablets 1-2 days before entering a country that poses a risk of malaria.

Continue to take the tablets every day during your stay there.

Continue taking the tablets after you have returned home for 7 days.

To treat malaria

As a malaria treatment, adults should take 4 tablets once a day for 3 days.

How much a child will need to take will depend on their body weight. Malarone tablets are not recommended for children who weigh less than 11 kg.

  • 11-20 kg – 1 tablet once a day for 3 days
  • 21-30 kg – 2 tablets once a day for 3 days
  • 31-40 kg – 3 tablets once a day for 3 days
  • Over 40 kg – the same dose as for adults.

What if I take more than I am supposed to?

If you accidentally take too much Malarone, speak to your doctor or pharmacist for advice. If possible, take the medication packet with you.

What if I forget to take it?

To successfully treat malaria, it is very important that you take the full course of Malarone.

If you forget to take a dose, do not worry; just take it as soon as you remember and continue taking the tablets as normal.

Never take extra tablets to try and make up for missing a previous dose.

If you vomit after taking it

If you are sick within one hour after taking Malarone, take another dose straight away.

If you have to take extra tablets as a result of vomiting, you may need another prescription. It is vital that you complete a full course of Malarone to effectively prevent and treat malaria.

Malarone FAQ's

What does it do?

Malaria tablets like Malarone contain atovaquone and proguanil, which are both used to treat and prevent malaria. It works by helping to prevent the growth of parasites in a human body's red blood cells. The parasites that cause malaria enter your body through mosquito bites and enter the bloodstream.

Who is at risk of malaria?

Anyone can catch malaria; even if you live in a country that does not have malaria, you can catch the disease if you travel to a country that does have it. In rare cases, you can also get malaria as a result of a blood transfusion. An infected mother may also pass the disease to her baby before or during the birth. Anyone travelling to a country with mosquitoes is at risk of catching malaria from bites. People with little or no immunity to malaria include pregnant women, young children and travellers who have come from places that malaria is not a risk. These groups of people are more likely to become severely ill and die. Those who live or travel to rural areas without easy access to healthcare are also at a great risk. 90% of malaria-related deaths occur in Africa south of the Sahara.

Why Malarone?

Malarone can both prevent malaria and treat the disease if you catch it while abroad. It contains both proguanil hydrochloride and atovaquone, which are anti-parasitic drugs that actively inhibit the plasmodium parasite that causes malaria. If you already have malaria, this medicine will stop the parasite's ability to reproduce in the bloodstream, making it easier for you to recover. It works by blocking the enzyme within the parasite, meaning it cannot reproduce.

How effective is it?

Malarone is one of the most commonly prescribed medicines for treating malaria. However, while Malarone tablets are an effective treatment, no medication is 100% effective for treating or preventing this disease. To stand the best chance of preventing and fighting malaria, you must make sure you take the tablets consistently and as directed.

What should I do if I experience side effects from Malarone?

Like all medicines, Malarone tablets come with the risk of certain side effects, although these will not affect everyone who takes them. Please read the 'Side Effects' tab on this page for a list of reactions you may suffer. Speak to your doctor if any of these bother you or do not go away.

Allergic reactions after taking Malarone

If you suffer a serious allergic reaction, you must call 999 or go to A&E immediately. Signs of a serious allergic reaction include: You are wheezing, You are finding it difficult to speak or breathe, You have swelling in your face, mouth, lips, tongue or throat, You have tightness in your chest or throat, You develop a skin rash that may be red, itchy, swollen, blistered or peeling skin.

Who should not take Malarone?

Do not use this medication if: You are allergic to atovaquone, proguanil hydrochloride or any of the other ingredients in these tablets, you have severe kidney disease, your child weighs less than 11kg and is being treated for malaria.

Should I purchase branded or generic Malarone?

There is no difference between generic Malarone or the branded version other than the name. Generic Malarone should have the same ingredients as the branded Malarone, so generic Malarone tablets should be just as effective at treating and preventing malaria.You can buy Malarone from Medicine Direct following an online consultation. Once an online doctor prescribes you the correct tablets, you can order them from our online pharmacy straight away. Order by 2pm for next day delivery.

Is Malarone only available on prescription?

Yes, you need a prescription for this medicine. After a consultation with an online doctor, you can purchase Malarone from our online pharmacy. All of our doctors are registered with the General Medical Council, which means they can prescribe medicine just like your local GP. We offer free delivery and your medication can be with you in a few short days. Order by 2pm and you can have it the very next day. To prevent Malaria, you will need to start taking this medicine 1-2 days before entering the country that poses a high risk.

How should I store Malarone when travelling?

Store these tablets in a room temperature environment, away from heat and moisture.

Can Malarone be used to treat malaria?

Malarone is one of the most common forms of malaria tablets prescribed to treat the disease. It can also be prescribed to prevent malaria when travelling abroad. You can order this medicine online at Medicine Direct following a consultation with a registered online doctor. Our doses start from 16 tablets and range up to 12 months' worth of medication, depending on how long you are travelling for.

Malarone alternatives

Currently, there are no non-prescription alternatives to Malarone, although you could try the following to prevent catching malaria while abroad: Use sunscreen that can help to prevent mosquito bites, Use mosquito repellent that contains DEET, When you go to sleep, use a mosquito net that has been treated with insecticide.

Malarone Side Effects

Rarer side effects of Malarone may include:

  • An increased heart rate
  • Panic attacks, crying
  • Seizures (fits)
  • Cholestasis
  • Hepatitis
  • Nightmares
  • Indigestion
  • Severe mental problems where you lose contact with reality or cannot think clearly
  • Inflammation of the blood vessels
  • Increased skin sensitivity to sunlight
  • Blisters
  • Mouth ulcers
  • Skin peeling

Uncommon side effects also include:

  • Anxiety
  • Hair loss
  • Hives
  • Heart palpitations
  • Swelling or redness of the mouth

A rare side effect may also include hallucinations.

Speak to your doctor if any of the above reactions bother you.

Serious allergic reaction

In rare cases, it is possible to suffer a serious allergic reaction to Malarone. You should either call 999 or go to A&E straight away if you experience any of the following symptoms:

  • You are wheezing
  • You are finding it difficult to speak or breathe
  • You have swelling in your face, mouth, lips, tongue or throat
  • You have tightness in your chest or throat
  • You develop a skin rash that may be red, itchy, swollen, blistered or peeling skin

You may require immediate treatment in hospital.

Please read the patient information leaflet, which will come with your medication, for full details on side effects. If you have any concerns about side effects, please speak to your doctor or pharmacist before you start using this medication.

Malarone Warnings and drug interactions

Malarone may interact with other medicines, which may hinder its effectiveness and increase your risk of side effects.

Before taking a new medicine, you must always tell your doctor if you are already taking any other form of medication. This includes both prescription and non-prescription medicines, vitamins, supplements or herbal remedies.

In particular, tell your doctor if you are currently taking any of the following:

  • Etoposide, which is used to treat cancer
  • Metoclopramide, which is used to treat nausea and vomiting
  • The antibiotics tetracycline, rifampicin and rifabutin
  • Any medicines to stop blood clotting, such as warfarin
  • Efavirenz or certain highly active protease-inhibitors used to treat HIV

Find out if you are taking any medications that interact with atovaquone and any medications that interact with proguanil.

If you have any concerns or questions at all about whether Malarone is a suitable medicine for you to use, we strongly advise you to discuss these with your doctor before you start to take it.

Pregnancy and breastfeeding

Malarone should not be taken by women who are pregnant unless specifically instructed to do so by a doctor.

Always make sure your doctor is aware if you are currently pregnant, think you might be pregnant, or are trying to get pregnant.

Malarone's ingredients can get into your breast milk and may harm your baby. Women who are breastfeeding should not take these tablets.

We recommend using BUMPS for additional information on taking this medication during pregnancy and breastfeeding. 

Malarone Ingredients

The main active ingredients within this medicine are: Atovaquone and Proguanil hydrochloride

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Sonia Khna MPharm: 2076091

Updated on: 07/06/2021

This content has been written by James Nuttall and has been medically reviewed by our Pharmacist Sonia Khan.

Sonia Khan Pharmacist at Medicine Direct

Sonia Khan
MPharm: 2076091


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