If you are suffering from acid reflux, Pantoprazole could remedy your condition. It is a medicine which provides relief when there is excessive acid in the stomach. This can be painful and create ulcers and erode the lining of the throat.


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Pantoprazole 20 mg is a gastro-resistant tablet which is used to reduce the over production of stomach acid. This means that Pantoprazole is commonly administered to effectively treat acid-related ailments and diseases of the intestine, oesophagus and stomach. It is suitable for the treatment of adults and adolescents over the age of 12.

What is Pantoprazole used to treat?

  • Reflux oesophagitis. This condition is when the tube which connects your throat and stomach (your oesophagus) becomes inflamed and your body regurgitates stomach acid.
  • In combination with two antibiotics (eradication therapy) for the treatment of Infections caused by the bacterium Helicobacter pylori in those who have duodenal and stomach ulcers.
  • Stomach ulcers and duodenal ulcers.
  • Conditions which cause the body to produce excessive amounts of stomach acid.
  • Gastritis, although acid reflux and gastritis are completely separate medical conditions, Gastritis can cause many of the same symptoms which is why they are treated using the same medication.

Pantoprazole Dosage

Pantoprazole is available in two strengths 20mg and 40mg. It is orally taken either in the form of tablets or granules in some cases.

Pantoprazole 20mg

This lower strength is used regularly with children and also able to be doubled up in dosage to provide 40mg of Pantoprazole to patients. Swallowing two smaller tablets rather than the slightly larger 40mg may be more appealing to some customers. It is also used as a long term management medicine to prevent acid reflux.

Pantoprazole 40mg

This is a stronger version of the Pantoprazole and so is used to treat acid related problems more powerfully than the 20mg strength medicine. It is possible to take two 20mg Pantoprazole tablets as a 40mg dose rather than buying 40mg tablets. If suffering from acid reflux, your doctor may increase your 20mg prescription to 40mg is your problems persist or return.

What are the potential Pantoprazole side effects?

As with all medicines, taking them comes with a risk of side effects.

If you experience any of the following symptoms you must stop taking it and inform your doctor immediately, or if the symptoms are more serious seek immediate medical help from your local hospital.

Common side effects:

  • Headache
  • Nausea or vomiting
  • Diarrhoea
  • Symptoms of a severe cold including sneezing
  • Stomach discomfort and pain
  • Joint aches
  • Increased body temperature 

Uncommon side effects:

  • Skin conditions
  • Yellowing of the skin/ whites of the eyes, fever,
  • Enlarged kidneys which can sometimes cause painful urination and lower back pain which can then lead to kidney failure.
  • Headache, dizziness, diarrhoea, feeling sick, vomiting, bloating and flatulence, constipation,
  • feeling weak or fatigued or generally unwell, difficulty sleeping due to a decrease in magnesium levels
  • Pains in joints or muscles
  • The swelling of extremities
  • Depression
  • Breast enlargement in males.
  • Unintentional weight loss
  • Disorientated, hallucinations or confusion
  • A decreased sodium, magnesium, calcium or potassium level in your blood, muscle spasms as a result of a change to electrolytes, the sensation of tingling, prickling, pins and needles burning sensation or a numbness, a rash with potentially joint pain.
  • Severe allergic reactions can take the form of the tongue swelling, appearance of hives, difficulty swallowing or breathing, facial swelling, dizziness, accelerated heart beat and heavy sweating. Please note these adverse effects are very rare, happening only in around 1 out of 1,000 people. If you believe you are suffering from a severe allergic reaction you must seek medical assistance immediately.

Pantoprazole Pregnancy and Breastfeeding Warnings

You must tell your doctor before taking Pantoprazole if you are already pregnant or are trying to conceive.

Although there is no evidence to suggest Pantoprazole is harmful during pregnancy, the drugs method of action is very similar to Pantoprazole which is considered safe to use during pregnancy.

Pregnancy is one of the main causes of acid reflux. Pantoprazole is considered safe to take during pregnancy and breastfeeding.

As acid reflux is usually caused by a number of lifestyle choices most commonly diet, for pregnant women; the safer and first point of call should always be to make small changes to lifestyle and diet. Your doctor or pharmacist will advise you on making slight changes to your diet such as avoiding foods that cause acid reflux and also eating more foods that help with the symptoms of acid reflux.

If after making slight changes to your lifestyle you are still experiencing symptoms, you may be recommended pantoprazole or a similar medication such as Omeprazole

Pantoprazole and Breastfeeding

Pantoprazole is considered safe to take when breastfeeding. Although Pantoprazole will travel into the breast milk and be consumed by your baby, this only equates to a small amount, which is not harmful to the baby.

Extra caution should be taken if your baby is premature or has been born with health problems. Please inform your GP if you are pregnant and taking Pantoprazole or any other proton pump inhibitor.

Pantoprazole Drug Interactions

If you are taking any other medications, it is possible that these may affect the way Pantoprazole works.

Please inform your doctor if you are taking any other medications. The most common medications that can interact with the effectiveness of Pantoprazole are:

  • Digoxin used to increase the strength of heartbeats and used for a variety of heart conditions
  • HIV medication
  • The anti-epilepsy drug Phenytoin
  • Rifampicin
  • Blood thinning medications such as Clopidogrel and Warfarin
  • Methotrexate used to treat Psoriasis and Rheumatoid Arthritis
  • Anti fungal medications such as Intraconazole, Ketoconazole, Posaconazole, Voriconazole

Do not take Omeprazole if you are taking St John’s Wort, the herbal remedy used to treat depression. This will cause Omeprazole to stop working as well as it should.

A complete list of the medicines that Pantoprazole can interact with will be detailed in the product information leaflet located inside the box of your medication.

What dosage of Pantoprazole should I take?

As a general rule, doctors will recommend to take one Pantoprazole 20mg tablet per day with a glass of water, an hour before eating a meal. If followed as a regular routine, you can expect to see relief from symptoms within 2-4 weeks. Do not take a double dose in order to cover for a previous missed tablet.

The usual recommended dosages of Pantoprazole are listed below:

  • Treatment of gastro-oesophageal reflux disease (heartburn, acid reflux, damage to throat)

Pantoprazole is generally prescribed as one tablet a day. Your doctor will tell you how long you should continue the course of medicine, the length of the course is normally from 2-4 weeks to a potential further 4 weeks if your symptoms are still present.

  • Prevention of the return of Acid reflux

One 20mg tablet a day. If your symptoms persist or return your doctor may advice you to increase the strength to 40mg for a set amount of time before returning back to the lower dosage of 20mg.

You should not take Pantoprazole if you allergic to any of the ingredients listed in this medicine including pantoprazole itself or know you have been allergic to other proton pump inhibitors in the past.

Please ensure you talk to your doctor or pharmacist before buying and consuming Pantoprazole. This is especially important if you have:

  • B12 Deficiencies. All acid diminishing agents such as Pantoprazole have the potential to lessen your body’s absorption of the vitamin B12. Therefore, it is not recommended that you take Pantoprazole if you are aware of having lowered stores of B12 or have risk factors for a reduction of the vitamin.
  • Taking HIV protease inhibitors such as atazanavir.
  • Osteoporosis or are taking corticosteroids (as these increase the risk of osteoporosis. Please note that when Pantoprazole is taken over a period of more than a year your chances of the obtaining a fracture of the hip, wrist of spine is increased.
  • Scheduled to have a particular blood test
  • Ever having had suffered with a skin reaction after using another form of stomach acid reducing medicine. If a skin rash does occur whilst you are taking Pantoprazole please seek medical advice, particularly if it develops on skin which is exposed to the sun.
  • Joint pain
  • Severe liver problems.

What is the recommended way to store Pantoprazole?

Store in conditions below 30oc. Make sure it is out of reach of children. Do not use past expiry date. Do not dispose of medicines through wastewater

Pantoprazole vs Omeprazole

Pantoprazole and Omeprazole of the 2 most common forms of acid relux medication in the UK. Both medicines work in a very similar way, with ingredients contained within each medication also being very similar. Both medications supress the amount of acid that the stomach produces and as a result reduces the signs of painful symptoms within an indivdual that uses it.

You can buy Omeprazole 20mg capsules online at Medicine Direct using our online doctors service.

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