Premique

What is Premique?

Premique is a combined form of hormone replacement therapy (HRT). It is prescribed for women who are going through the menopause. The two active ingredients in Premique are medroxyprogesterone acetate and conjugated oestrogens, which mimic the female sex hormones oestrogen and progesterone.

You can buy Premique from Medicine Direct following an online consultation with a registered doctor. If you order online by 2pm, we are able to offer you free next day delivery. We sell Premique as a 0.3mg dosage in packets of 84 tablets.

What is Premique used to treat?

Premique is a hormone replacement therapy (HRT) designed to help ease the symptoms of the menopause. All women will go through the menopause, usually between the ages of 45 and 55. During this time, your ovaries will produce less and less oestrogen, which stops your menstrual cycle.

While the menopause is a natural part of a woman's ageing process, it can have a large impact on your daily life, manifesting itself in various physical symptoms.

Symptoms of the menopause include:

• Night sweats
• Hot flushes
• Vaginal dryness
• Dryness of the eyes
• Osteoporosis
• Insomnia
• Depression
• Irritability

Symptoms generally last for around four years, although they will begin several years before you start the menopause.

What are the benefits of taking Premique?

A treatment like Premique eases the symptoms of the menopause by supplementing the hormones that your body no longer naturally produces. Some HRT treatments are oestrogen-only, but this can lead to complications in women who still have a uterus. Premique also contains medroxyprogesterone acetate, which means you will not have monthly bleeding, but the medication will balance the effects of added oestrogen in your system.

Premique, like all HRT medicines, will not prevent women who are still fertile from becoming pregnant. If you are under the age of 50, you are still considered to be fertile until two years after your final menstrual cycle.

Who can take Premique?

You should not take Premique if any of the following applies to you:

• You are allergic to medroxyprogesterone acetate, conjugated oestrogens or any other ingredients contained in this medicine
• You have any unexplained vaginal bleeding
• You have or have ever had a blood clot in a vein or the lungs
• You have ever had breast cancer, or you are suspected of having it
• You have or are suspected of having cancer that is oestrogen-sensitive, such as cancer of the womb lining
• You have any blood clotting disorders
• You have excessive thickening of the womb lining that has not been treated
• You have the inherited blood problem, porphyria
• You have or have recently had a disease that was caused by blood clots in the arteries, including a heart attack, stroke or angina
• You have or have ever had a liver disease and your liver function tests have not gone back to normal

Possible side effects

As with all medication, Premique does come with certain side effects, although not everyone who takes it will experience them.

Common adverse effects may include:

• Breast pain
• Depression
• Increase or decrease in weight
• Muscle and joint pain
• Breast tenderness or swelling
• Nipple discharge
• Changes in your triglyceride levels

Less common reactions can include:

• Vaginal thrush
• Headaches or migraine
• Nausea, bloating or abdominal pain
• Mood changes
• Changes in vaginal discharge or menstrual flow
• Changes in your sex drive
• Facial or ankle swelling
• Dizziness
• Blood clots in your veins
• Itchiness
• Acne
• Gallbladder disease
• Hair loss
• Difficulty wearing contact lenses

Speak to your doctor if any of these reactions bother you or do not go away.

Please note, these lists are not exhaustive. Refer to the Side Effects tab for a list of the rarer and more serious reactions you may suffer. Always read the patient information leaflet for a comprehensive list of unwanted effects.