Sumatriptan Tablets (50mg & 100mg)

  • Treats migraines
  • Very fast acting
  • Generic (cheaper) version of Imigran

Please note brand received may vary

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From As low as £15.99

Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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prescription included

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order before 2pm

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Quick migraine facts

  • 1 in 5 women suffer from migraines
  • 1 in 15 men suffer from migraines
  • Migraines last between 4 - 72 hours
  • There are 190,000 migraine attacks every day in the UK
  • Around 10 million people in the UK suffer from migraines

Sources: NHS England | NICE | NHS

What is Sumatriptan?

Sumatriptan is an effective and fast-acting medicine used for treating migraines and cluster headaches. It is part of a group of medicines called triptans, or serotonin (5-HT1) agonists.

It is the generic version of the drug Imigran, used to treat migraines. Triptans are prescribed for migraine sufferers to help them cope with the changes in the brain caused by this condition. By contracting blood vessels, triptans are able to stabilise brain chemicals and alleviate the pain brought on by migraines.

Other forms of this medicine include Imigran nasal spray and an injection.

What is Sumatriptan used to treat?

Sumatriptan cannot cure cluster headaches or migraines, nor can it prevent the oncoming of these afflictions. However, it is very effective in lessening the pain caused by these conditinos, alleviating the symptoms and allowing you to go about your everyday life without interruption from chronic pain.

While it is not classed as a painkiller, the medicine can be used as one if nonsteroidal anti-inflammatory drugs (NSAIDs) or painkillers have not effectively lessened your symptoms.

Sumatriptan typically gets to work within 30 minutes of being taken.

How does Sumatriptan work?

This medicine stabilises several chemical changes within the brain during a migraine attack, reducing your symptoms.

Changes in the brain which cause migraines are thought to involve the widening of blood vessels within the brain. Sumatriptan contains the active ingredient sumatriptan succinate, which causes your brain's blood vessels to contract to their normal size, thus alleviating the symptoms of a migraine.

By stimulating the serotonin receptors in your brain, it causes the surrounding muscles to contract, lessening the pain of a migraine attack.

How to take Sumatriptan

Take one tablet as soon as you start to feel the symptoms of a migraine attack coming on.

If your symptoms return or the initial dose is ineffective, a second dose can be taken after two hours.

Do not take more than three 100mg tablets or six 50mg tablets in 24 hours.

Swallow Sumatriptan tablets whole with a drink of water. Do not crush or chew them.

Always read the patient information leaflet before you start to take Sumatriptan. This leaflet will contain full details on how to take this medication. Ask your doctor for guidance if you are unsure.

How long does Sumatriptan take to work?

Sumatriptan tablets usually take between 30 to 60 minutes to start relieving migraine symptoms.

Who can take Sumatriptan tablets?

You should not take Sumatriptan tablets if you suffer from any of the following conditions or allergies:

  • You have high blood pressure
  • You have recently used ergotamine or similar medicines, or MAO inhibitors
  • You have any heart conditions (such as heart attacks, angina or tachyarrhythmia)
  • You have seizures or fits
  • You are allergic to Sumatriptan, Triptans 5-HT1, antimigraine agents, or any other ingredients
  • You have a severely reduced liver function or liver disease

You are not advised to take Sumatriptan tablets if you intend to drive or operate machinery. Migraines often cause drowsiness and dizziness, so you should avoid driving a car or operating any type of machinery until you feel better.

Sumatriptan can also have an adverse effect on anybody who is taking antidepressants. If you are taking antidepressants, you should consult your doctor before you start taking this medication.

You can eat and drink as normal while taking Sumatriptan as alcohol does not affect the medicine. However, during any headache attack it is always best to avoid any alcohol as it can sometimes be the trigger for a migraine or cluster headache.

Sumatriptan is considered to be a safe treatment for migraines in pregnant women. Sumatriptan can also be taken during breastfeeding as minimal amounts are excreeted into the breasmilk.

Sumatriptan common side effects

Like all medicines, Sumatriptan can cause side effects, although most people experience none at all, or only minor ones, these can include:

  • Nausea and/or vomiting
  • Dizziness or feeling unsteady on your feet
  • Tiredness
  • Feeling hot or cold
  • Facialflushing

If any of these issues bother you or last for more than a few days, you should consult your doctor or pharmacist.

Can you buy Sumatriptan over the counter?

You can purchase this medicine when you have a prescription from your doctor. It is not for sale over the counter.

Can you buy Sumatriptan online in the UK?

A prescription-only medicine (POM), you can buy Sumatriptan online from Medicine Direct if you have been diagnosed with migraines in the past. All you need to do is complete our simple and confidential online questionnaire, which will be assessed by one of our certified prescribers.

Sumatriptan 50mg or 100mg doses are available to be purchased from our online pharmacy. If you order before 2pm we can offer next day delivery on your medicine.

Never buy medicine online unless you order from a registered pharmacy, like Medicine Direct.

Sumatriptan alternatives

Medicine Direct stocks a number of alternative triptan medicines if Sumatriptan is not suitable for you. You can also order medicines like Almotriptan and Zolmitriptan from our online pharmacy by filling out our online medical questionnaire. Once one of our prescribers has checked your answers, your order will then be processed.

Imigran nasal sprays, which contain sumatriptan as the active ingredient, are also available to be bought from our online pharmacy. The nasal spray works to relieve migraines and is a good alternative for people who have trouble swallowing tablets.

Non-prescription alternatives like Anadin Extra and Migraleve Pink can be bought from our pharmacy, too.

View our full range of migraine treatments on the Migraine product page.

Sumatriptan Dosage 

All of our doctors and Pharmacists follow NICE guidelines when prescribing Sumatriptan 500/100mg tablets.

Sumatriptan tablets are only used to treat migraines and are available as a prescription-only medicine (POM) as either 50mg or 100mg tablets. Your first dose should be taken only when the pain has actually started, not before, as this can lead to symptoms of “aura”, which are the temporary warning symptoms before a migraine. Do not take Sumatriptan as a preventative measure against the onset of migraines.

Sumatriptan 50mg tablets are the regular starting dose for most people who experience migraine pain; this dosage should be sufficient to relieve most of the symptoms brought on by migraines, without needing to repeat the dose. If you suffer from severe migraines, or 50mg is not effective enough, you may prefer to try Sumatriptan 100mg strength tablets.

You should swallow Sumatriptan tablets whole and take them as soon as possible after your migraine pain has started. This will help to reduce the symptoms in the shortest period of time. The medicine should begin to work between 30 and 60 minutes after being taken, but if required the dose can be repeated after a minimum of 2 hours.

As with any medicine you buy, you should always read the information leaflet thoroughly before taking any dose. Do not take more than the prescribed amount of Sumatriptan within the same 24 hours.

Sumatriptan Side Effects

With all medicines, Sumatriptan has side effects. Most of these side effects are very mild and most people do not experience many or any of them.

Common side effects of Sumatriptan do not generally last long and include:

  • Nausea and/or vomiting
  • Dizziness or feeling unsteady on your feet
  • Tiredness
  • Feeling hot or cold
  • Face flushing red

In very rare cases, some people experience serious side effects. You should stop taking Sumatriptan and contact your doctor straight away if you experience any of the following:

  • Feelings of warmth or cold in your face, arms, legs or chest
  • Unusual feelings of heaviness in your face, arms, legs or chest
  • Tightness or tingling in your face, arms, legs or chest

It is possible, in rare cases, to have a serious allergic reaction to taking Sumatriptan. If you experience of the below, you should call 999 or go to A&E immediately:

  • Tightness in the chest or throat
  • Wheezing
  • Skin rash, itchy, red, swollen, peeling or blistered skin
  • Trouble breathing or speaking
  • Swelling in the mouth, face, lips, tongue or throat

If any of these symptoms occur, you could be having a serious allergic reaction and may require urgent treatment in hospital.

For the full list of side effects, you should read the patient information leaflet inside your medicine's packet.

Sumatriptan Warnings and drug interactions

Sumatriptan is generally considered to be a safe form of medication; it has been used for many years and has proven an effective way of tackling the symptoms of migraines.

It should be noted that Sumatriptan (Imigran) can cause your blood vessels to narrow, temporarily. For this reason, people who have had problems with poor circulation, a history of angina, heart attacks, strokes or mini-strokes should not take Sumatriptan. In rare situations, Sumatriptan can trigger serious heart problems even in people who have never had circulation problems.

You should check with your GP before taking Sumatriptan if you are a heavy smoker, a woman who has had the menopause or a man over the age of 40.

Migraines are, in some rare cases, associated with loss of vision, loss of speech and paralysis.

You should always see a GP for a diagnosis before you self-medicate for a headache. You should not take Sumatriptan in any of the below instances:

  • When headaches are different from previous ones or they show new symptoms
  • When headaches are more frequent and last longer
  • When headaches start for the first time over the age of 40

Do not take Sumatriptan tablets if:

  • You have high blood pressure
  • You have severely reduced liver function
  • You are allergic to Sumatriptan or any of the ingredients
  • You use, or have recently used ergotamine or similar medicines (e.g. methsergide maleate) or MAO inhibitors (like moclobemide or selegiline)

Sumatriptan in some cases may interact with other drugs, it is recommended to read the complete list of drug interactions before taking this medicine.

Pregnancy and breastfeeding

While there is not enough research to say for certain, Sumatriptan is not believed to be harmful during pregnancy. You should consult your doctor about potential benefits and dangers of taking the medicine before you take it.

It is usually safe to take Sumatriptan while breastfeeding, as only small amounts of the medicine go into the breast milk. You are advised to speak to your doctor if your baby was premature or has any health problems. Similarly, if you are trying to get pregnant, you should talk to your doctor before taking Sumatriptan. We recommend BUMPs for additional information.

Sumatriptan Ingredients

The main active ingredient within this medicine is: Sumatriptan succinate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Published on: 12/10/2020

Updated on: 27/07/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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