Clobetasone Ointment 0.05%

  • Used to treat inflammatory skin conditions
  • Moderate strength steroid cream/ointment
  • Reduces redness, itching and inflammation of the skin

Please note brand received may vary

Do you have a preference?
From As low as £15.99

Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

All-inclusive service

prescription included

Fast next day delivery

order before 2pm

UK registered pharmacy

and team of dispensers

What is Clobetasone?

Clobetasone is an ointment that is used as a treatment for inflammatory skin conditions, such as eczema or dermatitis. It contains the active ingredient clobetasone butyrate, which is a moderately potent corticosteroid.

It is often sold as the brand name, Eumovate.

You can buy Clobetasone Ointment from Medicine Direct once you have completed an online consultation with one of our registered doctors. After assessing your symptoms and medical history, the doctor will prescribe this medication if they believe it to be the most suitable for you to use.

You can then order it from our UK-based online pharmacy. Place your order by 2pm and we can also offer you next day delivery, absolutely free.

What is Clobetasone 0.05 Ointment used to treat?

Clobetasone 0.05 Ointment is used to treat inflammatory skin conditions, such as:

  • eczema 
  • dermatitis
  • nappy rash
  • psoriasis
  • insect bites or stings

The active ingredient, clobetasone butyrate, is a corticosteroid, which is an anti-inflammatory medicine. Inflammation of the skin occurs when your body releases inflammatory chemicals as a response to an allergy or irritation. These chemicals widen your blood vessels, which makes the skin swell and become painful or itchy.

Clobetasone 0.05 Ointment works by inhibiting cells from releasing large amounts of these chemicals.

Who can and can't use Clobetasone?

Clobetasone is safe to be used by most adults and children aged 12 years and above.

You should not use Clobetasone on children under the age of 12 unless a doctor has specifically prescribed it for them.

Do not use Clobetasone without speaking to your pharmacist or doctor if:

  • You are allergic to clobetasone butyrate, cetostearyl alcohol, chlorocresol or any of the other ingredients contained in this medicine (please see the Ingredients tab for full details)
  • You have ever had an allergic reaction to Clobetasone or any other medicines
  • You have acne or rosacea
  • You have an eye infection
  • You have a skin infection, cuts, broken skin, or itchy skin that is not inflamed or red (using Clobetasone may make these infections worse, or cause them to spread)

Dosage and Directions

Our pharmacists and prescribers follow NICE guidelines when prescribing clobetasome ointment.

Always apply Clobetasone 0.05 Ointment exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly before you start to use it. Speak to your doctor or pharmacist for further guidance if you are still not sure.

How much you will need to use will depend on the size of the affected area of skin.

Gently apply a thin layer of the ointment to the affected area(s) of skin. Gently rub the ointment in, ensuring it is properly absorbed into the skin.

Apply this product once or twice a day; as your symptoms start to improve, you can decrease the dose.

Do not apply this product to your face unless specifically instructed to do so by your doctor.

How and when to use it

  1. Spread the ointment in a thin layer over the irritated skin.
  2. Gently rub it into the skin in the direction your hair grows.
  3. Take care not to get the medicine into broken skin or cuts.
  4. Make sure the treatment covers the whole of the affected area(s), not just the worst parts.
  5. Wash your hands after applying the medicine, unless your hands are the treatment area.

Do not apply a moisturiser or any other product for at least 30 minutes after using Clobetasone.

If you are using Clobetasone for nappy rash, do not put the nappy on straight after applying it. This will help to prevent side effects.

If you are using a plaster or dressing, wait for at least 10 minutes after applying Clobetasone before you put it on.

What if I forget to put it on?

If you forget to apply this medicine, don't worry. Just apply it as soon as you remember.

If you only remember within a few hours of your next scheduled dose, just skip the dose you missed and continue using Clobetasone as usual.

Is it safe to buy Clobetasone online?

It is perfectly safe to order Clobetasone online at Medicine Direct. We are a fully registered UK pharmacy, regulated by the General Pharmaceutical Council (GPhC). This means we can guarantee genuine versions of the medication we stock, all of which is safe to use.

How do I buy Clobetasone online?

To purchase Clobetasone from our online pharmacy, just complete a simple online consultation with one of our certified medical professionals. They will assess your symptoms and medical history and prescribe the most suitable treatment for your specific case.

What are the advantages of buying Clobetasone online?

Ordering online with our registered pharmacy removes the need for you to wait days, or even weeks, for an appointment with your local GP. You can forego the need for examinations by completing one of our simple online consultations with a certified pharmacist or doctor. They will prescribe the most appropriate treatment for your condition, which you can order from our online pharmacy the very same day. All of our medical team are registered with the General Medical Council (GMC), General Pharmaceutical Council (GPhC) and the MHRA, so they can prescribe medicine just like your local GP.

What does the price include?

The price includes an online consultation with a registered medical professional and the medicine you are prescribed.

When will my skin get better?

Your skin should start to improve after using this medicine for a few days. You may need to apply it for a few weeks.

How long can I use Clobetasone for?

This will depend on why you are using it. For the likes of insect bites, nappy rash and dermatitis, you will probably need to use it for up to one week. Long-term problems like eczema may need this product for longer periods, under a doctor's supervision. If your child has been using this medicine and has not got better after 7 days, take them back to the doctor.

Why is it not recommended for faces?

The face's skin is delicate, so this medicine may make it thinner, making it damaged. This is noticeable and may not be able to be reversed. Do not use Clobetasone on your face unless you have been prescribed to do so by your doctor. You are advised not to apply it to your skin for longer than 5 days if you are prescribed it.

Is it safe to use for a long time?

Your doctor will normally recommend you stop using this product once your skin problem has improved. Using this medicine for a long time means it gets into your bloodstream, which can cause side effects in some cases. If you have been using Clobetasone for a long time, your doctor might gradually reduce your dose before you stop using it completely.

Can I drink alcohol with it?

Yes, it is okay to drink alcohol with Clobetasone

Is there any food or drink I need to avoid?

No, your diet does not need to change while using this medicine.

Can I still have vaccinations?

Yes, you can still have vaccinations. Make sure the doctor or nurse is aware that you are using Clobetasone, so they can avoid injecting into the affected area.

Will it affect my fertility?

There is no evidence to show Clobetasone affects male or female fertility.

Will it affect my contraception?

No, it does not affect any form of contraception.

Can I drive or ride a bike?

This medicine does not make you sleepy, so it should be safe to drive and cycle.

Can steroids make eczema worse?

Steroid medicines reduce inflammation in the skin, reducing symptoms. They are not a cure for the condition. If you think your condition is getting worse after a week of using Clobetasone, speak to your doctor. When the treatment stops, conditions like eczema or psoriasis may flare up again. This can be avoided by reducing how much ointment you apply gradually.

Side effects

Like all medicines, Clobetasone has the risk of side effects, although not everyone gets them.

Some people may suffer a burning or stinging sensation for a few minutes when they apply the ointment to their skin. However, this should stop happening when you have been using it for a few days.

Speak to your doctor if this problem bothers you or does not go away.

Please note, this is not an exhaustive list of information.

Please refer to the Side Effects tab on this page for information on rarer and serious reactions you may suffer while using Clobetasone.

Serious Side Effects

The serious side effects of Clobetasone will occur in 1 in 10,000 people who use it.

You are more likely to suffer a serious side effect if you apply the ointment over a large patch of skin for extended periods of time.

Stop using Clobetasone and seek medical attention immediately if you experience any of the following:

  • You have any new eyesight problems after you have started to use Clobetasone
  • You are using this product to treat psoriasis and you get raised bumps under the skin, which are filled with pus
  • You feel more thirsty or hungry than usual, confused, sleepy, need to urinate more often, start breathing quickly or your breath smells of fruit, you have hot flushes (these can be signs of high blood sugar)
  • Your skin becomes red or swollen, you have white patches on your skin or yellow fluid weeps from the skin (these could be symptoms of a new skin infection, or the existing one getting worse)

Prolonged use of Clobetasone can thin your skin or give you stretch marks. If you do get stretch marks, they will likely be permanent, although they will normally fade in time.

Children and teenagers

In very rare cases children and teenagers who use Clobetasone for an extended period may experience slowing down in growth. This is because the medicine is a steroid.

Your child's doctor will monitor their weight and height while this medicine is being used.

If you are worried, please speak to your doctor, who will be able to explain the risks and benefits associated with this product.

Serious allergic reaction

In rare cases, you may suffer a serious allergic reaction to Clobetasone and require immediate treatment in hospital.

Stop using this product and call 999 or go to A&E straight away if:

  • You are wheezing
  • You have swelling in your face, mouth, throat, lips or tongue
  • You are finding it difficult to breathe or speak
  • You have a skin rash that may have red, itchy, swollen, blistered or peeling skin
  • You have tightness in your chest or throat

Please note, these lists may not be exhaustive. Always read the patient information leaflet for full details on side effects.

If you are concerned about side effects, we strongly advise you to discuss these concerns with your pharmacist or doctor before you start to use it.

Warnings and Drug Interactions

Pregnancy and breastfeeding

You are not advised to use Clobetasone 0.05 Ointment without speaking to your doctor if you are pregnant. Make sure your pharmacist or doctor is aware if you are either currently pregnant, think you might be pregnant or are trying to get pregnant.

It is generally safe to use Clobetasone while breastfeeding. If you are using the product on your breasts, thoroughly wash off any remaining ointment before you breastfeed your baby. Wash your hands before touching your nipple or the baby's mouth.

We recommend BUMPS for additional information.

Cautions with other medicines

It is unlikely Clobetasone will interact with other medicines. Nonetheless, always tell your pharmacist or doctor if you are taking any other prescription or non-prescription medicines, herbal remedies, vitamins or supplements, before you start to take a new medication.

In particular, make sure they aware if you are taking:

  • Ritonavir
  • Itraconazole

Always read the patient information leaflet before you start to use a new medicine.

If you have any questions or concerns about using this product, please do not hesitate to discuss them with your pharmacist or doctor.



The active ingredient contained in this ointment is clobetasone butyrate (0.05% w/w).

Inactive ingredients are: Liquid paraffin and white soft paraffin.

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Updated on: 09/06/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

How it works - get your medicine in 3 simple steps

  • 1 Choose your treatment Select the treatment or medication you need and answer a few questions online regarding your condition.
  • 2 Online consultation Our Independent Prescribers will review your questions and assess your suitability for the medication.
  • 3 Receive your delivery Your medication is dispensed and delivered directly to you from our UK based Pharmacy.

No Related guide Posts

Customers have rated us Excellent on trustpilot
We’re here to help

If you need any help, don't hesitate to get in touch, we would love to hear from you!

Copyright © 2021 Pharmacorp LTD. All rights reserved.