Mebeverine Hydrochloride Tablets (135mg)

  • Relaxes the muscles in and around the gut
  • Eases the pain and cramps caused by IBS
  • Works fast to ease symptoms

Please note brand received may vary

From As low as £18.99

Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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order before 2pm

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What is Mebeverine?

Mebeverine hydrochloride is a medication known as an antispasmodic.

It comes available as tablets, capsules or a liquid.

What is Mebeverine used to treat?

Mebeverine is usually prescribed to adults suffering with symptoms of irritable bowel syndrome (IBS).

Common symptoms of irritable bowel syndrome (IBS) include painful stomach cramps; this medication works by relaxing the muscles in and around the gut, relieving the pain associated with IBS.

It is available to buy on prescription and you can also buy Mebeverine tablets from a pharmacy like Medicine Direct. If you order with us before 2pm, we can offer you next day delivery on your tablets.

Who can take Mebeverine?

Mebeverine can be taken by most adults and children who are at least 10 years old. However, it may not be suitable for everyone.

You should tell your doctor or pharmacist before you use this medication if one or more of the following applies to you:

  • You are pregnant, breastfeeding or trying for a baby
  • You are constipated because of paralytic ileus
  • You have had an allergic reaction to Mebeverine or any other medication in the past
  • You have a rare inherited condition that makes it impossible for you to digest galactose (a sugar found in lactose)
  • You are aged 40 years old or over
  • You have blood in your stools
  • You have or think you may have food poisoning (particularly if you have recently been abroad)
  • You are pale or feel tired
  • You have a loss of appetite or have recently lost weight
  • You have unusual vaginal bleeding or vaginal discharge
  • You feel sick or are vomiting

Possible Side Effects

Like all medicines, Mebeverine comes with the risk of side effects, although not everyone is going to get them. Most side effects are very mild and do not last for long.

It rarely happens, but the main side effect associated with Mebeverine is a mild, itchy skin rash or swelling.

Take an antihistamine if you experience these symptoms. You can purchase these from your local supermarket or pharmacy, check with a pharmacist to see which is most suitable to treat the rash.

If these side effects bother you or do not go away, you should stop taking the medicine and speak to your doctor.

Please note, this may not be the only adverse effect of taking Mebeverine tablets. Always read the patient information leaflet that will come with your medicine.

More information can be found on the Side Effects tab on this page.

Mebeverine Dosage

The standard dosage for Mebeverine tablets is 135mg. You will normally be instructed by your doctor to take one tablet 3 times a day.

Our pharmacists and prescribers follow NICE prescribing guidelines when prescribing Mebeverine.

Take the tablets 20 minutes before a meal; if you are told to take it twice a day, take it before breakfast and dinner. If you are told to take it 3 times a day, take it before breakfast, lunch and dinner.

You should start to feel the effects of these tablets after about an hour.

Mebeverine tablets should be swallowed whole with a glass of water.

What if I take more than I am supposed to?

Accidentally taking an extra dose of Mebeverine is unlikely to do you any harm, but you should contact your doctor or pharmacist if you become worried or you take more than one extra dose of the medicine.

What if I forget to take it?

If you forget to take a dose of this treatment, just skip the missed out dose and continue to take it as usual when it is time for your next scheduled dose.

Never take an extra dose of medicine to try and make up for missing an earlier dose; this will not work and can increase your chances of experiencing serious adverse effects.

To get into a routine of taking this medication, it should be taken at the same time each day. Some people find it helps to set an alarm to remind them to take it.

How long will I need to take it for?

Normally, you will only need to take Mebeverine if you are having a flare-up of irritable bowel syndrome symptoms.

You should stop taking the medicine when you feel better. This could take up to 2 weeks to happen.

If your IBS symptoms have not improved after 2 weeks, or if they get any worse, you should go back to your doctor.

Mebeverine FAQ's

Can Mebeverine help constipation?


Mebeverine alone does not have a laxative effect, but you can purchase a combination of mebeverine with ispaghula husk, which can help with constipation relating to IBS symptoms.

Can I get Mebeverine on the NHS?


This medicine is available to purchase on the NHS when you have been prescribed it by a doctor to treat irritable bowel syndrome.

How do Mebeverine tablets work?


Mebeverine tablets contain the active ingredient mebeverine hydrochloride, which is a type of antispasmodic medicine. One of the most common symptoms of IBS is stomach pain, caused when your intestine goes into spasm and squeezes too tightly. Mebeverine works by relaxing the muscles in and around your gut, which relieves these symptoms.

How long does it take to work?


You should take one tablet as instructed by your doctor. This medication will start to work after about one hour, and you should start to feel better between one and three hours after taking it. You should take the tablet 20 minutes before you have a meal.

What are the side effects of Mebeverine?


The most common side effect of this medicine is a mild itchy skin rash, but not everyone will experience this. Undesired effects are rare with this medication, and most people who do get them do not experience them for very long. Please, refer to the Side Effects tab on this page for a list of more serious symptoms you should look out for while taking Mebeverine. You should always make sure you thoroughly read the patient information sheet, which will come with your medicine before you start to take it, for the full list of possible adverse reactions you may experience. If any adverse symptoms bother you or don't go away, you should contact your doctor as soon as you can.

Can I drink alcohol with it?


Yes, it is safe to drink alcohol while using this medicine.

Should I avoid any particular types of food or drink?


You can eat as you normally would while taking Mebeverine. However, it should be noted that lifestyle changes like a healthier diet can help to improve IBS.

How do I buy Mebeverine tablets online?


You can order these tablets from an online pharmacy like Medicine Direct. After an online consultation with one of our certified doctors, you will be issued with a prescription to purchase it. We sell the 135mg dose in packets of either 100 or 200 tablets. If you order before 2pm, we can offer you next day delivery on your order.

How does Mebeverine compare to other IBS treatments like Buscopan, Colofac and Duspatalin?


Mebeverine is the same as Colofac and Duspatalin; these are brand names for the same medicine and they are all used to treat IBS. Buscopan is made up of hyoscine butylbromide and is used to treat bladder spasms and abdominal pain. You should not take this at the same time as Mebeverine as they are both antispasmodic medications.

Mebeverine Side Effects

The main side effects of this drug can be found on the main product page.

In rare cases, it is possible that you may experience a severe allergic reaction to this medication.

If you exhibit any of the below symptoms, you could require immediate treatment in hospital and should either call 999 or go to A&E, straight away:

  • You have a skin rash that is red, swollen, itchy, blistered or peeling
  • You have tightness in the chest or throat
  • You have swelling of the throat, face, lips, mouth or tongue
  • You are finding it difficult to breathe or talk
  • You are wheezing

Always read the patient information leaflet for the full list of potential side effects associated with any medicine.

Mebeverine Warnings and drug interactions

It is generally safe to take Mebeverine with other medications, as well as over the counter painkillers like paracetamol and ibuprofen.

You should not take it if you are already using any other medicines to treat IBS symptoms, as these treatments work in the same way. Doing so can make the two medicines interact with each other, which can either render them both ineffective or cause side effects.

However, as with any medicine you have been prescribed, you should always make sure that your doctor is aware of any other medicines you are already taking before you start to use a new one. This includes both prescription and non-prescription medication, herbal remedies, vitamins and supplements.

If you have any doubts or concerns at all, we strongly advise you to discuss them with your doctor before you start using Mebeverine.

Pregnancy and breastfeeding

Mebeverine medications are not usually recommended for women who are pregnant as there is not enough research to prove that it is safe for them to take.

If you suffer from IBS and are currently pregnant, think you might be pregnant, or are trying to get pregnant, you should speak to your doctor before you start to take it.

If you are breastfeeding, it should be safe for you to take Mebeverine, but you should still inform your doctor; they will be able to advise you on the best course of treatment for your symptoms.

Read more about taking Mebeverine during pregnancy and breastfeeding.

Mebeverine Ingredients

The active ingredient contained in this medication is mebeverine hydrochloride.

Other inactive ingredients also contained include: microcrystalline cellulose, lactose monohydrate, povidone, talc, magnesium stearate and sodium starch glycolate

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Sonia Khan MPharm: 2076091

Published on: 12/10/2020

Updated on: 25/05/2021

This content has been written by our Pharmacist Sonia Khan and has been medically reviewed by our Superintendent Pharmacist Hussain Abdeh

Sonia Khan
MPharm: 2076091

Pharmacist

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