Xyloproct Ointment (20g)

  • Reduces risk of infection
  • Contains both hydrocortisone and lidocaine
  • Relieves swelling and discomfort
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What is Xyloproct?

Xyloproct is a topical treatment that contains two medicines: lidocaine and hydrocortisone.

It is used in the short-term to relieve anal and vaginal itching, as well as treat the symptoms of haemorrhoids (piles).

Xyloproct ointment is able to reduce the risk of infection as well as relieve swelling and discomfort. It can be applied several times a day to both the outside and inside of the back passage.

This is a prescription-only medicine (POM) that can be used by both adults and children of all ages. 

What is Xyloproct used to treat?

Xyloproct ointment can be used by both adults and children to relieve the uncomfortable symptoms of haemorrhoids, such as swelling and itching. It can also be prescribed to relieve itching in the back passage and the vagina.

This medicine should only be used in the short-term.

Haemorrhoids (also known as piles) occur when the veins inside and around the anus swell. Haemorrhoids are a common problem that can affect people of all ages. They will normally go away on their own, but sometimes an ointment or cream is required for the pain and swelling.

You may be suffering from piles if you have any of these symptoms:

  • Bleeding or swelling in the anus
  • Pain or discomfort in or around the anus
  • Lumps around your anus
  • Itching or irritation in or around the anus

Common symptoms of Piles (Haemorrhoids)

40% of individuals with Haemorrhoids do not display any symptoms (asymptomatic). Symptoms of haemorrhoids can differ depending on the type of haemorrhoid you are suffering from.

Type of Haemorrhoid


Internal haemorrhoids

  • Bright red blood on your poo or on the tissue paper after wiping
  • A lump or bulge near the opening of the anus, this may hurt when you poo

External haemorrhoids

  • Pain
  • Itching
  • Swelling
  • Bleeding

How does Xyloproct work?

Xyloproct contains two active ingredients, one of which is lidocaine, which belongs to a group of medicines known as local anaesthetics. Lidocaine works as a numbing agent and reduces the nerve impulses travelling from the affected area to the brain. This relieves the pain associated with haemorrhoids.

The second active ingredient is hydrocortisone, which belongs to a group of medicines called corticosteroids. These medicines have anti-inflammatory properties, so hydrocortisone will work to reduce the swelling caused by piles.

How to use Xyloproct

Always use this medicine as your doctor has told you. Read the patient information leaflet for full instructions.

Usually, you will be instructed to apply Xyloproct to the affected area several times a day. Up to a third of the tube (6g) can be applied each day.

Xyloproct should be used in the short-term. If you have been prescribed this medicine for a longer treatment period, it can be used for up to three weeks, although you may need a break during this time.

If you need to use the ointment internally, use the applicator which will come with Xyloproct to apply the medicine. Clean the applicator thoroughly after each time you use it.

Wash your hands before and after applying the ointment.

Using the applicator

Xyloproct ointment comes with an applicator and your doctor or pharmacist will tell you whether or not you will need to use it.

If you are told to use the applicator, make sure you do not insert too much ointment into the rectum. This is particularly important if Xyloproct has been prescribed as a treatment for a child.

If you do need to use the applicator, be sure to clean it thorougly after each use.

Who can use Xyloproct ointment?

Xyloproct is an effective treatment for the symptoms of both internal and external haemorrhoids. It can be used by adults and children when they have been prescribed it, but it is not suitable for everyone to use.

Do not use Xyloproct ointment if any of the following apply to you:

  • You are allergic to lidocaine, hydrocortisone or any of the other ingredients contained in this medication (please refer to the Ingredients tab for a full list of substances)
  • You have ever suffered an allergic reaction to other corticosteroids or local anaesthetics in the past
  • You have an infection in the affected area that is not being treated
  • You are not currently in hospital and are taking any medicine to treat an uneven heartbeat

Talk to your doctor or pharmacist before you start to use this medicine if any of the following applies to you:

  • You have thin or fragile skin in the area you will need to apply the ointment to
  • You are pregnant or breastfeeding
  • You have an infection in the affected area where the ointment would be applied
  • Your doctor has told you that you suffer from the rare inherited disease 'porphyria', or anyone in your family has it

Read the patient information leaflet, which will accompany your medicine, for complete details on who Xyloproct may not be suitable for. If you are not sure whether Xyloproct is suitable for you, please talk to your doctor or pharmacist before you begin your course of treatment.

See the 'Warnings' tab for information on precautions and drug interactions to be aware of while using this ointment.

Possible side effects

Like all medication, Xyloproct can cause side effects, although these will not appear in everyone who uses it.

Speak to your doctor straight away if you get any of the following reactions:

  • Soreness in the anus
  • Bleeding from the anus

Please note, this list is not exhaustive. Please refer to the Side Effects tab for more information on reactions you may experience.

Can you buy Xyloproct over the counter?

No, Xyloproct is a prescription-only medicine (POM). It cannot be bought over the counter.

Can you buy Xyloproct online in the UK?

Xyloproct is only available on prescription. You can buy Xyloproct from Medicine Direct by completing a short and confidential online consultation. Your answers will be assessed by one of our certified prescribers, who will make sure it is safe for you to use.

Next day delivery is available if your order is placed by 2pm.

For your own safety, you should not buy medicine online from anywhere other than regulated pharmacies, like Medicine Direct. We are fully regulated by the General Pharmaceutical Council (GPhC), which means we can guarantee that all of our medicine is safe and approved for sale in the UK.

Xyloproct alternatives

If Xyloproct is not a suitable treatment for your haemorrhoids, do not worry. There are many different medications available for treating this problem.

Medicine Direct has a number of topical treatments that contain a corticosteroid and local anaesthetic combination like Xyloproct, and which will work in the same way to alleviate piles. These medicines are also only available on prescription, but you can order them after completing an online consultation to make sure your desired treatment is suitable for you.

Over the counter medication like Anusol Plus HC ointment and suppositories are available, too. These medicines contain six active ingredients to give comprehensive relief from the inflammation and discomfort caused by haemorrhoids. You can buy these medicines from our pharmacy without a prescription, but you will still need to fill out an online questionnaire.

Making healthy changes to your lifestyle can help to prevent and treat piles. Adopting a high fibre diet is one way that this condition can be treated and prevented. The likes of wholegrain bread, porridge oats, potatoes with their skins on and wholegrain muesli are all excellent sources of fibre that can be easily incorporated into a person's diet.

You should also take regular exercise, drink lots of water and limit how much caffeine and alcohol you consume.

Xyloproct Ointment Dosage and Directions 

Our pharmacists and prescribers follow NICE guidelines when prescribing Xyloproct ointment.

What if I use more than I'm supposed to?

Seek medical attention as soon as possible if you have used more Xyloproct than you were supposed to. If a child has been given too much ointment, it is imperative that you talk to a medical professional as a matter of urgency. Some children who have been given too much of this medicine have experienced fits as a result.

What does Xyloproct contain?

Xyloproct ointment contains lidocaine, hydrocortisone, zinc oxide, aluminium acetate, stearyl alcohol, cetyl alcohol, purified water and macrogol (3350 and 400). Talk to your doctor or pharmacist before using Xyloproct if you are allergic to any of the ingredients listed here.

How do I store Xyloproct?

Keep this ointment out of the sight and reach of children. Store it in temperatures below 25C. Do not keep using it past the expiry date, which can be found on the tube. The expiry date refers to the last day of the stated month. If you have any ointment remaining after you finish your course of treatment, ask your pharmacist for advice on how to safely dispose of any remaining medicine. This will help to protect the environment. Do not dispose of any excess medication via household waste or wastewater.

How long should I apply it for?

Talk to your doctor or pharmacist if your symptoms have not improved after seven days. Xyloproct should not be used for extended periods of time.

What if my piles don't go away?

If you are still suffering from piles after the course of treatment outlined by your doctor or pharmacist, please talk to them for advice. Do not keep using this medicine for longer than you were instructed to.

Will it affect my contraception?

There is no evidence to suggest that this treatment will have any effect on contraception. However, you should tell your doctor or pharmacist if you are using any form of contraceptive medication, think you might be pregnant or are trying to get pregnant.

Is there any food or drink I need to avoid?

You do not need to alter your diet while using this medication. However, if you are suffering from haemorrhoids (piles), adding more fibre to your diet is one way that this condition can be treated and prevented. Eating more wholegrain bread, porridge oats, potatoes with their skins on, brown pasta and brown rice and wholegrain muesli are all excellent sources of fibre that can be easily incorporated into a person's diet.

Can lifestyle changes affect piles?

Many cases of piles will ease without needing treatment, but you can make certain changes to improve the condition. Often, piles can occur from straining when having a bowel movement; the need to strain is often brought on by constipation. This can be avoided by exercising regularly, eating plenty of fruit and vegetables, as well as foods that are high in fibre, drinking lots of water each day and going to the toilet as soon as you feel the need to.

Xyloproct ointment Side Effects

The following side effects have been reported by some people who used Xyloproct:

  • Redness, swelling and itching at the site of application

Talk to your doctor if you get any of these symptoms.

Serious allergic reaction

If you get any of the following symptoms, you may be suffering a serious allergic reaction and require immediate treatment in hospital.

Call 999 or go to A&E straight away if:

  • You are wheezing
  • You have swelling in your throat, mouth, face, lips or tongue
  • You are finding it hard to breathe or speak
  • You have tightness in your chest or throat
  • You develop a skin rash that may included red, itchy, swollen, blistered or peeling skin

Always read the patient information leaflet for a full list of side effects, as well as information on how to deal with them. If you have any concerns about side effects, please do not hesitate to contact your doctor or pharmacist.

Xyloproct Ointment Warnings

What precautions/interactions should I be aware of with Xyloproct?

Xyloproct is not known to affect other medicines, but you should still tell your doctor or pharmacist if you are already using any other prescription or non-prescription medication before you start using Xyloproct. This includes herbal remedies, vitamins and supplements.

It is especially important that you tell them if you are already using any of the following medicines:

  • Any other local anaesthetic medicines
  • Any medicines used to treat an uneven heartbeat, such as amiodarone or sotalol

Xyloproct contains cetyl alcohol and stearyl alcohol, which may cause local skin reactions, such as contact dermatitis.

Driving and using machines

Xyloproct is unlikely to impair your ability to drive or operate machinery. However, your co-ordination or alertness may be affected temporarily, depending on how much you apply. If you experience these side effects, you must not drive, operate machinery or ride a bike until you feel better. If these reactions persist, talk to your doctor or pharmacist.

Always read the patient information leaflet for full details on warnings and drug interactions. If you have any questions or concerns, please speak to your doctor or pharmacist before you start using this treatment.

Pregnancy and breastfeeding

Talk to your doctor before using Xyloproct if you are currently pregnant, think you might be pregnant, are trying to get pregnant or are breastfeeding.

We recommend BUMPs for more information.

Xyloproct ointment Ingredients

The main active ingredients within this medicine are: Lidocaine and Hydrocortisone acetate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Updated on: 02/08/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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