Betamethasone with Clioquinol Cream

  • Used to treat a number of skin conditions
  • Contains Betamethasone Valerate
  • Reduces inflammation and irritation of the skin

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What is Betamethasone with Clioquinol Cream?

Betamethasone with Clioquinol Cream is a combination of two medicines, the corticosteroid betamethasone valerate and the antifungal/antibacterial medicine clioquinol.

When combined, these medicines provide effective treatment for skin conditions like eczema, insect bites and psoriasis.

This cream is a prescription-only medicine (POM).

What is Betamethasone with Clioquinol Cream used to treat?

This medicine is used to treat a variety of skin conditions, including psoriasis, eczema, insect bites and other skin rashes.

Betamethasone with Clioquinol Cream works by actively reducing swelling. It is also effective in helping to protect the skin from infection, which can be a particularly high risk if you have used airtight dressings to cover the skin problem, as this creates a breeding ground for bacteria.

How does Betamethasone with Clioquinol Cream work?

This medicine contains two active ingredients, betamethasone valerate and clioquinol. Betamethasone valerate is a strong corticosteroid, which works to reduce the skin's inflammation and irritation. It has anti-inflammatory properties, which can reduce the swelling of skin by inhibiting the release of chemicals that cause inflammation.

Clioquinol has both antibacterial and antifungal properties. This allows it to prevent infection by stopping bacteria from growing and multiplying.

How to use Betamethasone with Clioquinol Cream

Always apply Betamethasone with Clioquinol Cream exactly as instructed by your doctor or pharmacist.

Read the patient information leaflet thoroughly and speak to your doctor or pharmacist for further guidance if you are still not sure of how to use it.

This medicine is for external use only.


Use this product once or twice a day. Wash your hands before and after applying the medicine.

Apply a thin layer of the cream carefully to the affected area(s).

If you have been using any airtight dressings on the affected skin, you should clean the area before using the cream. Apply a new dressing after you have applied the cream.

If you have not noticed any improvement after using this product for a few days, please speak to your doctor.

Continued use of this product may cause an infection to become resistant to clioquinol.

If you are using any other topical medicines alongside this one, you should wait for at least 30 minutes between applying one treatment before applying the other. This will stop the medicine from being diluted.

What if I use too much?

If you over-apply this cream, wipe away the surplus and contact your doctor if you suffer any reactions as a result of over-applying it.

What if I forget to apply it?

If you accidentally forget to apply this cream, don't worry. Just apply it as soon as you remember, as long as it is not almost time for your next scheduled application. If it is nearly time for your next application, just wait until then and keep using the cream as usual.

Never apply two doses to try and make up for missing a previous application.

If you are using any other topical treatments at the same time as using this product, always leave a gap of at least 30 minutes between applying the different treatments.

Who can use Betamethasone with Clioquinol Cream?

Betamethasone with Clioquinol Cream provides effective relief from a number of skin conditions. However, it may not be suitable for everyone to use.

Do not use this product if you are allergic to clioquinol, betamethasone valerate or any of the other ingredients contained in this cream (please refer to the Ingredients tab for full details).

Do not use this medicine on inflamed skin around the genitals or anus, unless your doctor has specifically instructed you to do so.

Always read the patient information leaflet and packaging thoroughly for full information on who this medicine is suitable for. Speak to your doctor or pharmacist if you are still unsure.

Can you buy Betamethasone with Clioquinol Cream over the counter?

No, you cannot buy Betamethasone with Clioquinol Cream over the counter. You can only purchase this medicine when you have a prescription from a doctor.

Can you buy Betamethasone with Clioquinol Cream online in the UK?

Yes, you can buy Betamethasone with Clioquinol Cream from Medicine Direct after a simple online consultation. As this medicine is only available on prescription, you will first need to complete a confidential questionnaire for one of our prescribers to review. This is to make sure that this medicine is the correct treatment for your condition.

You can then place your order with our online pharmacy; order by 2pm and you will benefit from our free next day delivery service.

To ensure you only purchase approved and safe medicine, only order medication online from regulated pharmacies like Medicine Direct. We are fully regulated by the General Pharmaceutical Council and the MHRA, meaning we sell only safe and approved medical products.

Betamethasone with Clioquinol Cream alternatives

The main active ingredient, Betamethasone Valerate is available as a cream and is available to buy at Medicine Direct.

Many medicines are available for the treatment of skin conditions like eczema and psoriasis. A similar medicine also available from Medicine Direct is Betamethasone with Neomycin Cream. Neomycin is an antibiotic medicine that works to stop bacteria from producing the proteins it needs to survive. This helps to kill infections of the skin.

Other topical corticosteroid creams and ointments can be ordered from our online pharmacy after completing an online consultation questionnaire. Creams and ointments like Betnovate and Clobetasone work to relieve inflammation and irritation swiftly and effectively.

Fucidin Cream contains an antibiotic medicine (fusidic acid), which is able to treat infected skin within one week. This makes it an effective treatment for when eczema and other skin problems become infected.

Dosage and Directions

Our pharmacists and prescribers follow NICE guidelines when prescribing Betamethasone with clioquinol cream.

Storage instructions

Store this medicine well out of the reach and sight of children.

Store in a cool, dry place and do not use after the expiry date, which can be found on the product's packaging.

Can I use this cream on my face?

Do not apply Betamethasone with Clioquinol Cream to your face unless your doctor tells you to. This is because steroids can thin the skin, which is a particular risk to the face as this skin is thinner than most other areas on your body.

How long should I use this cream for?

This cream should only be used in the short term to avoid thinning of the skin. If your skin problem has not got any better after a few days of using Betamethasone with Clioquinol Cream, tell your doctor.

Can I apply it to broken skin?

You should not apply this cream to skin that is broken, or that has cuts or burns.

Is betamethasone valerate an antibiotic?

No, betamethasone valerate is a corticosteroid. Clioquinol is an antibacterial/antifungal medicine; it is this ingredient that works to stop the bacteria from growing.

How long does it take to work?

Your skin should start to get better after a few days of use. Tell your doctor if you have not seen any improvement after using Betamethasone with Clioquinol Cream for a few days.

Can steroids make my eczema even worse?

Steroids do not cure eczema, they just work to reduce the inflammation that it causes, which works to make the symptoms more manageable. The clioquinol contained in this cream will work to fight the bacteria. However, if you believe that this cream is making your eczema worse rather than better, tell your doctor.

Is clioquinol good for the skin?

Clioquinol is an effective antibiotic/antibacterial medicine that can effectively treat various infections. However, you should only use it when your doctor advises.

Can Betamethasone lighten the skin?

Some people do experience skin lightening as a side effect while using topical medications containing betamethasone valerate. However, it must not be used as a skin lightening treatment. You should tell your doctor if you experience any changes to your skin pigmentation.

Can I have vaccinations while I’m using this cream?

Yes, you can still have vaccinations, although you should tell your doctor or nurse that you are using Betamethasone with Clioquinol Cream. This is so they can inject you in an area that is not being treated.

Can I drink alcohol while I’m using it?

It is safe to drink alcohol while using Betamethasone with Clioquinol Cream.

Side Effects

A list of milder side effects can be found on the main product page.

In rare cases, you may experience a serious allergic reaction to Betamethasone with Clioquinol Cream.

You must either go to A&E or dial 999 straight away if you notice any of the following symptoms:

  • You have tightness in your chest or throat
  • You have swelling in your face, throat, chest, lips or tongue
  • You have a skin rash that may have red, itchy, swollen, blistered or peeling skin
  • You are finding it hard to breathe or speak
  • You are wheezing

You may require immediate treatment in hospital.

Always read the patient information leaflet and medicine packaging for full details on side effects.

Please do not hesitate to speak to your doctor or pharmacist if you have any questions or concerns about side effects

Warnings and drug interactions

Before using this medicine, please inform your doctor or pharmacist if you are currently using any other form of medicine. This includes both prescription and non-prescription medication, herbal remedies, vitamins and supplements as some medicines can interact with the ingredient beatametasone.

Also, inform your doctor or pharmacist if you intend to take a new medicine while you are using this product.

If you suffer from any of the following conditions, Betamethasone and Clioquinol Cream can make them worse:

  • Viral infections, such as chicken pox, herpes or cold sores
  • Acne
  • Rosacea (flushing of the skin around your nose)
  • Perioral dermatitis (a rash around your mouth)
  • Bacterial infections
  • Fungal infections (such as athlete's foot or thrush)

You must not use this cream on inflamed skin around the anus or genitals unless your doctor has specifically instructed you to do so.

Exercise caution if you are applying the cream under a nappy or airtight dressing, as too much of the medicine may be absorbed into the skin. This increases the risk of suffering side effects.

Read the patient information leaflet and packaging thoroughly before you start to use a new medicine. If you have any questions or concerns, please do not hesitate to speak to your doctor or pharmacist.

Pregnancy and breastfeeding

Do not use this medicine without speaking to your doctor if you are currently pregnant, trying to get pregnant, think you might be pregnant, or are breastfeeding.

We recommend BUMPS for additonal information.


This medicine contains two active ingredients: Betamethasone valerate and clioquinol.

It also contains the following inactive ingredients: Cetomacrogol 1000, cetostearyl alcohol, white soft paraffin, liquid paraffin, sodium acid phosphate, phosphoric acid, sodium hydroxide and purified water.

Please speak to your doctor if you are allergic to any of the ingredients listed above, before you use this product.

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Medically reviewed by Hussain Abdeh MPharm: 2211840

Updated on: 10/06/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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