Betamethasone with Neomycin Cream

  • Relieves symptoms assosciated with dry skin conditions
  • Suitable for Eczema, dematitis and Psoriasis
  • Reduces inflammation and irritation of the skin

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What is Betamethasone with Neomycin Cream?

Betamethasone with Neomycin Cream is a topical treatment for skin conditions such as eczema, psoriasis, insect bites and various other types of rashes.

It contains two active ingredients, betamethasone valerate and neomycin sulphate, which work together to reduce irritation and stop the growth of bacteria.

Betamethasone with Neomycin cream is only available on prescription.

What is Betamethasone with Neomycin Cream used to treat?

Betamethasone with Neomycin Cream is a prescription-only topical corticosteroid treatment for various skin conditions including eczema, psoriasis and insect bites.

Corticosteroids possess anti-inflammatory properties which help to relieve inflammation of the skin that comes with conditions like insect bites and eczema.

Neomycin is an antibacterial medicine, meaning it helps to protect the body from infection and kill harmful bacteria. Essentially, it stops the bacteria from spreading on the surface of the skin.

How does Betamethasone with Neomycin Cream work?

The two medicines contained in this cream (betamethasone valerate and neomycin sulphate) each work in different ways to relieve the common symptoms associated with skin problems.

Betamethasone valerate is a powerful corticosteroid which effectively works to reduce irritation and inflammation of the skin, which are common problems for people who suffer from the likes of eczema, insect bites and psoriasis.

Neomycin sulphate is an antibiotic medicine which helps to treat the underlying problem by stopping the harmful bacteria from producing the necessary proteins they need to live. This kills the infection. Because some skin conditions can pose a serious risk of infection, the antibacterial properties of this medicine makes it a highly beneficial treatment.

How to use Betamethasone Valerate with Neomycin Cream

  1. Wash your hands before using the cream.
  2. Apply a thin layer of cream to the affected areas of skin two or three times a day. Gently massage the cream into the skin. This dose can be decreased as your symptoms start to improve.
  3. Unless you are treating your hands with the cream, wash them again after applying the treatment.

Follow your doctor’s dosage instructions when applying this cream. Refer to the patient information leaflet for further direction.

Do not use this medicine on children's skin or anyone's facial skin for longer than five days. Tell your doctor if you have not seen any improvement after a few days of use.

If you are using any other topical medicines at the same time as Betamethasone with Neomycin Cream, you should wait for at least 30 minutes after applying one topical treatment before you apply the next one.

Who can use Betamethasone with Neomycin Cream?

This product may not be suitable for everyone to use.

Do not use Betamethasone Valerate with Neomycin Cream unless your doctor has issued a prescription for you.

Do not use this product without speaking to your doctor if any of the following apply to you:

  • You are allergic to betamethasone valerate, neomycin sulphate or any of the other ingredients contained in this cream (please refer to the Ingredients tab for more information)
  • You are due to have surgery in the near future
  • You have any kidney problems
  • You are pregnant, trying to get pregnant or think you might be pregnant
  • You are breastfeeding

If you are using this medicine as a treatment for psoriasis, you will need to attend regular check-ups with your doctor.

This product must not be used on inflamed skin around the anus or genital area, unless a doctor has instructed you to do so.

This information is not exhaustive. Read the patient information leaflet for a full list of reasons why Betamethasone with Neomycin Cream may be unsuitable for you.

Can you buy Betamethasone with Neomycin Cream over the counter?

No, this cream is only available on prescription and cannot be bought over the counter.

Can you buy Betamethasone with Neomycin Cream online in the UK?

This is a prescription-only medicine (POM), but you can buy Betamethasone with Neomycin Cream online from Medicine Direct. You will first need to complete a confidential online questionnaire, which will be reviewed by one of our prescribers to ensure that this is a suitable medication for your condition.

Next day delivery is available on orders placed on our website by 2pm.

Never buy any type of medication online unless it is from a regulated pharmacy, like Medicine Direct. We are regulated by the General Pharmaceutical Council to ensure we sell nothing but genuine and approved medicine.

Betamethasone with Neomycin Cream alternatives

Betamethasone valerate is the active ingredient contained in a broad number of corticosteroid creams, several of which are available from our online pharmacy.

Another combination medicine available from Medicine Direct is Betamethasone with Clioquinol Cream. Clioquinol possesses both antibacterial and antifungal properties, meaning it can help to prevent infection by stopping the growth of bacteria. This cream is also only available on prescription.

Betamethasone is also available as a non branded cream on its own.

Branded creams and ointments also containing betamethasone valerate include Betnovate Cream/Ointment and Eumovate Cream/Ointment. These treatments provide relief from the symptoms of common skin problems like eczema and psoriasis.

View our Eczema page to see the full range of medicines we offer.

Dosage and Directions

Our pharmacists and prescribers follow NICE guidelines when prescribing Betamethasone with Neomycin Cream.

How to store

Store this product our of the sight and reach of children.

Do not store in conditions above 25C, and do not keep using after the expiry date, which can be found on the packaging.

Can you use too much of this cream?

Using too much of a steroid cream can cause thinning of the skin. This can also occur if it is used for long periods of time. If you have applied an excessive amount of cream to the skin, wipe off the excess and speak to your doctor if you experience any irritation.

How long does it take to work?

Your skin should start to improve after a few days of use. If you have been using Betamethasone with Neomycin Cream for a few days and have not seen any improvement, speak to your doctor.

Can Betamethasone make you tired?

If you experience tiredness while using this medication, speak to your doctor.

Is it safe to use in the long term?

You should not use a steroid cream for longer than your doctor tells you to. Corticosteroids like this can thin the skin and cause stretch marks.

Will my contraception be affected?

No, Betamethasone with Neomycin Cream does not have any effect on contraception, including the morning after pill.

Can I drink alcohol with it?

Yes, it is safe to drink alcohol while using this cream.

Can Betamethasone cause hair growth?

Some products containing betamethasone valerate as their active ingredient, such as scalp applications, can cause hair growth as a rare side effect. However, this does not occur in everyone and it should not be used as a hair growth treatment.

Is betamethasone an antifungal?

No, betamethasone valerate is not an antifungal, it is a corticosteroid. This cream will not work to treat fungal infections.

Can neomycin treat acne?

Neomycin is sometimes used as an ingredient in acne treatments. However, you should not use this cream as a treatment for acne. Speak to your doctor if you are suffering with acne; they will be able to recommend the most suitable treatment for you, which may include a combination of antibiotics and a topical medicine.

Will my fertility be affected?

No firm evidence exists to show that this cream affects male or female fertility.

Side effects

Like all medication, Betamethasone with Neomycin Cream comes with the risk of certain side effects, although these will not affect everyone who uses it.

Stop using the cream and seek medical attention if any of the below reactions bother you or do not go away as treatment progresses:

  • An itching or burning sensation at the application site
  • Bumps under the areas of skin that are affected by psoriasis

Please note, this list is not exhaustive. Please refer to the Side Effects tab for information on rarer and more serious adverse reactions you may get while using this cream.

Serious Side Effects

Information on more common side effects can be found on the main product page.

In rare cases, it is possible to suffer a severe allergic reaction to Betamethasone with Neomycin Cream.

You should stop using this product and either call 999 or go to A&E straight away if you get any of the following symptoms:

  • You have swelling in your face, mouth, tongue, lips or throat
  • You have tightness in your chest or throat
  • You are finding it difficult to speak or breathe
  • You are wheezing
  • You get a skin rash that may have red, itchy, swollen, blistered or peeling skin

You may be having a severe allergic reaction and require immediate treatment in hospital.

Please note, this list may not be exhaustive. Always read the patient information leaflet for full details on side effects and how to cope with them.

If you are concerned about side effects, we strongly advise you to speak to your doctor or pharmacist about them before you start using this medication.


Warnings and drug interactions

Before you start to use Betamethasone with Neomycin Cream, be sure to inform your doctor or pharmacist of any other medication you are currently using. This includes both prescription and non-prescription medication, herbal remedies, vitamins and supplements as some medicines can interact with the ingredient beatametasone and some medicines can interact with the ingredient neomycin.

If you suffer from any of the below conditions, this product may make them worse:

  • Acne
  • Perioral dermatitis
  • Viral infections such as herpes or chicken pox
  • Bacterial infections
  • Fungal infections, such as athlete's foot
  • Rosacea
  • External ear infections

Please speak to your doctor about the pros and cons of using Betamethasone with Neomycin Cream if you are currently being treated for any of the conditions listed above.

This medicine is prescription-only, and should not be used by anyone other than the person it was prescribed for.

Always read the patient information leaflet for full details on warnings and drug interactions. If you have any questions or concerns at all, we strongly advise you to discuss these with your doctor or pharmacist before you start to use this product.

Pregnancy and breastfeeding

This is a prescription-only medicine. Do not use this product if you are pregnant or breastfeeding unless your doctor has issued you a prescription.

Before you are issued a prescription, make sure your doctor is aware if:

  • You are currently pregnant
  • You are currently breastfeeding
  • You are trying to get pregnant
  • You think you might be pregnant

We recommend BUMPS for additonal information.


This medicine contains two active ingredients: Betamethasone valerate and neomycin sulphate.

The cream also contains the following inactive ingredients: Cetomacrogol 1000, chlorocresol, cetostearyl alcohol, white soft paraffin, liquid paraffin, sodium acid phosphate, phosphoric acid, sodium hydroxide, purified water.

Please speak to your doctor or pharmacist before using this cream if you are allergic to any of the ingredients listed here.

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Updated on: 05/08/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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