Efracea Modified Release Capsules - 40mg

  • Effectively treats Rosacea
  • Provide long term relief of Rosacea symptoms
  • Reduces redness and irritation
From As low as £21.99
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What is Efracea 40mg Modified Release Capsules?

Efracea contains the active ingredient doxycycline, which belongs to a group of medicines known as tetracycline antibiotics. Efracea is a slow-release formulation which can be used in the treatment of rosacea.

It is a prescription-only medicine and is suitable to be taken by adults and children who are aged 12 and above.

You can buy Efracea capsules from Medicine Direct after a simple and confidential online consultation with one of our qualified doctors. They will review your symptoms and medical history and issue a prescription for Efracea 40mg modified-release capsules if they believe it is the most suitable form of treatment for you to use.

You can then use this prescription to order your medicine from our UK registered online pharmacy. Place your order by 2pm and we can offer you next day delivery.

How does Efracea work?

Efracea modified-release capsules contain the tetracycline antibiotic, doxycycline as its active substance.

Rosacea is a lifelong skin condition for most people who suffer from it. In the majority of cases, it will flare up then go away for various periods of time. It generally appears on the face and comes with various symptoms, including:

  • Papules (small spots)
  • Blood vessels becoming visible through the skin
  • Thickening of the skin
  • Redness and flushing of the face
  • Spots filled with pus

Efracea capsules provide long-term relief from the symptoms of rosacea. The slow-release formulation of this medicine means that there is only a low dosage of doxycycline, so it is safe to be take Efracea for extended periods of time.

This medicine will work to calm the skin and reduce the redness and irritation that comes with rosacea. Some people who use Efracea may find that their symptoms disappear completely.

Is Efracea suitable for me?

Efracea is an effective treatment for rosacea, but it may not be suitable for everyone to use.

Do not take Efracea if any of the below apply to you:

  • You are allergic to doxycycline or any of the other ingredients contained in this medication (please refer to the Ingredients tab for full details)
  • You are allergic to any other medicine in the tetracycline family, including doxycycline and minocycline
  • You have a condition that causes a lack of acid in the stomach called achlorhydria
  • You have had surgery on the upper part of your gut

Efracea is not suitable for infants or children under the age of 12 years old.

Speak to your doctor before taking Efracea if:

  • You have colitis
  • You are prone to or have a history of candidiasis overgrowth
  • You have a fungal, oral or vaginal yeast infection
  • You have liver disease
  • Your doctor has told you that you are intolerant to certain sugars
  • You suffer from the muscle disease myasthenia gravis
  • You suffer from a form of rosacea which affects your eyes
  • You have oesophageal irritation or ulceration
  • You expose your skin to excessive/strong or artificial sunlight

Pregnancy and breastfeeding

Efracea is not suitable for women who are breastfeeding. This medicine may cause permanent teeth discolouration in the unborn baby.

Similarly, it may also cause tooth discolouration and reduce bone growth in any babies who are being breastfed. For this reason, mothers who are breastfeeding should not use Efracea for long periods.

If you are currently breastfeeding or pregnant, are trying to get pregnant or think you might be pregnant, please make sure you speak to your doctor before using Efracea.

Efracea Dosage and Directions

How to take Efracea

Always take Efracea exactly as instructed by your doctor. Read the patient information leaflet thoroughly and speak to your doctor or pharmacist if you are not sure.

The recommended dose of Efracea is one capsule a day, to be taken in the morning.

Take this medicine on an empty stomach, ideally at least one hour before a meal, or two hours after eating.

Directions of use

Swallow the capsules whole with a drink of water. Do not crush or chew them. Make sure you have a sufficient amount of water, to ensure that the capsules travel down your throat properly. This will avoid throat irritation.

To further avoid any throat irritation, it is best to be sat up straight or standing while taking Efracea.

Keep taking Efracea until your doctor tells you to stop.

If you take more than you are supposed to

Taking an overdose of Efracea may cause damage to your kidney, pancreas or liver. You should speak to your doctor or call 111 straight away if you take too much of this medicine.

If you forget to take it

If you accidentally miss a dose of Efracea, do not take a double dose to try and make up for missing a previous one.

Efracea FAQ's

What is Efracea?


Efracea contains the antibiotic doxycycline. It is a treatment for the skin condition rosacea.

How does Efracea treat rosacea?


Each Efracea capsule contains 40mg of the antibiotic doxycycline. This medicine is a modified-release formulation, which works to remove inflammation and other rosacea symptoms without affecting the rest of the body.

What is the best way to take Efracea?


Always take Efracea as instructed by your doctor. One capsule should be taken in the morning on an empty stomach. Try to leave at least one hour before eating or two hours after eating when taking this capsule. Efracea capsules can be made to be less effective if combined with certain types of food. Swallow the capsules whole with a drink of water. Do not crush or chew them. Always read the patient information leaflet for full instructions and talk to your doctor if you are unsure.

How do I know if Efracea is suitable for me?


Efracea is not suitable for everyone to take. This medicine is only available on prescription, so your doctor will ask you about any existing health problems and any other medication you may currently be taking, before they prescribe it for you. Details on reasons why it may not be suitable for you can be found on the main product page and on the Warnings tab.

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Like any medicine, Efracea comes with the risk of certain side effects, although not everyone will get them. The most common adverse effects of taking this medicine can include: Fungal infections; Inflammation of the sinuses; Inflammation of the nose and throat; Diarrhoea; Pain; Dry mouth; Back pain; Anxiety; High or increased blood pressure; Sinus headache; Changes in some blood tests; Pain in the upper abdomen; Headache; Increased pressure in the brain. Always read the patient information leaflet for full details.

Is it okay to drink alcohol while using Efracea?


Doxycycline can be made less effective if the patient consumes large amounts of alcohol. Drinking in moderation should not cause any problems, but speak to your doctor if you have any adverse effects.

Is it okay to take Efracea at the same time as other medications?


Certain medicines can interact with Efracea and increase the risk of health problems. If taken alongside any retinoids, there is a risk of increased skull pressure. Other medicines can also make Efracea capsules less effective. Inform your doctor if you are taking any other form of medication before you start your course of treatment. This includes any prescription or non-prescription medicines, herbal remedies, vitamins or supplements you may already be taking.

Are Efracea capsules available over the counter?


You can only buy Efracea capsules when you have been issued a prescription by a doctor. Complete a simple and confidential online consultation at Medicine Direct, and one of our registered doctors can give you a prescription for this medication if the believe it is the most suitable treatment for your case of rosacea. You can then place your order with our online pharmacy. Order by 2pm and your treatment will be with you the very next day.

How should I store Efracea capsules?


Store this medicine out of the sight and reach of children. Store it in the original packaging to keep it out of direct sunlight. Do not keep using it after the expiry date, which can be found on the packet. The expiry date refers to the last day of the stated month.

Can I use Efracea capsules while I am pregnant?


Using this treatment while pregnant may cause permanent staining of your child's teeth. You should not use Efracea while pregnant. Make sure your doctor is aware if: You are currently pregnant or breastfeeding. You think you might be pregnant. You are trying to get pregnant.

Can I drive while using Efracea capsules?


Efracea capsules should not directly impair your ability to drive. However, if you suffer any adverse reactions that impair your judgement or vision, you are strongly advised not to drive, ride a bike or operate machinery until you feel better again.

Efracea side effects

Like all prescription and non-prescription medicines, Efracea comes with the risk of certain side effects, although not everyone who takes it will get them.

Common side effects of taking Efracea may include:

  • Fungal infections
  • Inflammation of the sinuses
  • Inflammation of the nose and throat
  • Pain
  • Back pain
  • Anxiety
  • High or increased blood pressure
  • Diarrhoea
  • Sinus headache
  • Changes in some blood tests
  • Pain in the upper abdomen
  • Headache
  • Increased pressure in the brain

Please speak to your doctor if any of these side effects bother you or do not go away.

Serious Side Effects

Rarer side effects of Efracia will only affect between 1 and 10 people in every 10,000 who use it. However, they may include:

  • Allergic reaction throughout your body
  • Skin rash or hives
  • Changes in the number of certain types of blood cells
  • Liver damage
  • Increased level of urea in your blood
  • Inflammation of the membrane which surrounds the heart
  • Increased pressure in the brain
  • Dry mouth
  • Nausea, vomiting, anorexia or diarrhoea
  • Abnormal skin reactions when exposed to sunlight

Below is a list of reactions which are extremely rare, affecting less than 1 in every 10,000 users of Efracea:

  • Haemolytic anaemia (damage to your red blood cells)
  • Brown-black discolouration of the thyroid tissue (this is microscopic and has been reported in people who use Efracea for long periods of time. The thyroid function will remain normal)
  • Difficulty swallowing
  • Inflammation of the skin, which may cause it to flake
  • Inflammation of the intestine
  • Inflammation of the gullet
  • Ulceration of the gullet
  • Increased pressure in infants' brains
  • Worsening of systemic lupus erythematosus (SLE), which is a disease of the immune system
  • Inflammation of the tongue

The following side effect may happen at an unknown frequency:

  • Loosening of the nail from nail bed after being exposed to the sun

Speak to your doctor immediately if you suffer any of the reactions listed here.

Severe allergic reaction

In rare cases, it is possible to suffer a severe allergic reaction to Efracea.

You must dial 999 or go to A&E straight away if you get any of the following symptoms:

  • You are finding it difficult to breathe or speak
  • You have swelling in your face, mouth, throat, lips or tongue
  • You have a skin rash that may have red, itchy, swollen, blistered or peeling skin
  • You have tightness in your chest or throat
  • You are wheezing

You may be having a severe allergic reaction and require immediate treatment in hospital.

These lists may not be exhaustive. Always read the patient information leaflet for comprehensive details on side effects.

If you are worried about getting side effects from this treatment, please do not hesitate to speak to your doctor or pharmacist about your concerns.

Efracea Warnings and Drug Interactions

Certain other medicines may interact with Efracea. Before using this treatment, make sure that you inform your doctor if you are currently taking (or have recently taken) any other form of medication. This includes both prescription and non-prescription medication, herbal remedies, vitamins and supplements.

Efracea may make certain antibiotics less effective, including penicillin.

Do not take any antacids or multivitamins, or any products containing any of the following for at least 2 to 3 hours after taking Efracea. These may reduce its effectiveness if you take them at the same time:

  • Any products containing calcium (milk, dairy products, fruit juices which contain calcium)
  • Aluminium
  • Magnesium (such as quinapril tablets for high blood pressure)
  • Iron or bismuth
  • Cholestyramine
  • Activated charcoal or sucralfate

Do not take Efracea alongside isotretinoin (a prescription treatment for severe acne); this may risk increased pressure in the brain.

If you are taking any blood thinners, your doctor may need to adjust your dose.

If you are taking any diabetes treatments, your doctor may also need to adjust your dose.

Do not use any treatments for heartburn or ulcers for at least 2 hours after using Efracea.

Taking barbiturates, such as painkillers or sleeping pills, may reduce how long Efracea stays in your system. Inform your doctor if you are taking:

  • Primidone
  • Cyclosporin
  • Carbamazepine
  • Rifampicin
  • Diphenylhydantoin
  • Phenytoin

There is a risk of serious damage to the kidneys if Efracea is taken alongside the general anaesthetic methoxyfluorane.

These capsules contain sugar (sucrose) and allura red AC aluminium lake (E129). Do not use Efracea without speaking to your doctor if you have been told that you have an intolerance to certain sugars. Allura red AC aluminium lake (E129) may cause allergic reactions.

Efracea and food

Swallow these capsules with plenty of water to wash it down completely.

Do not swallow the capsules with milk or any dairy products; these contain calcium which can reduce Efracea's effectiveness.

Do not consume any dairy products for at least 2 to 3 hours after you have taken Efracea.

Driving and operating machinery

There is no evidence to show that Efracea will directly impair your ability to drive. Nonetheless, if you have any side effects which impair your vision or judgement, you should not drive, cycle or operate machinery until you feel better again.

Always read the patient information leaflet for full details on warnings and drug interactions. If you have any questions or concerns, we strongly advise you to discuss these with your doctor or pharmacist.

Order safely

Medicine Direct is fully registered with the General Pharmaceutical Council (GPhC). This means that we can promise our customers safe and genuine medication when they order with us.

The members of our medical team are registered with the General Pharmaceutical Council (GPhC), the General Medical Council (GMC) and the MHRA. They are fully qualified to recommend treatments for medical conditions, just like your local GP. All of our doctors and pharmacists have experience in working in NHS hospitals or other professional clinical settings.

We offer a swift delivery service on all of our medical products, which are despatched from our UK-based pharmacy. Not only that, but if you order by 2pm, we can offer you next day delivery.

Efracea Ingredients

The active ingredient contained in these capsules is doxycycline.

Efracea also contains the following ingredients: hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1), triethyl citrate, talc, hypromellose, titanium dioxide, macrogol 400, yellow iron oxide, red iron oxide, polysorbate 80, sugar spheres (maize starch, sucrose).

The capsules are made from: gelatin, black iron oxide, red iron oxide, yellow iron oxide, titanium dioxide.

The printing ink contains: shellac, propylene glycol, black iron oxide, indigo carmine aluminium lake, allura red AC aluminium lake (E129), brilliant blue FCF aluminium lake, D & C yellow no. 10 aluminium lake.

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You're reviewing:Efracea Modified Release Capsules - 40mg

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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