• Fights against acne causing bacteria
  • Works within 6 - 8 weeks
  • Visibly reduces acne, redness and inflammation

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Minocycline 100mg Tablets

Acne affects 95% of us between the ages of 11 and 30. There is no quick fix when it comes to treating acne, instead; acne treatments are intended to fight against the acne causing bacteria and gradually clear it from the surface of the skin. You can buy Minocycline 100mg tablets online from Medicine Direct, complete your online consultation and get started on your acne treatment plan.

What is Minocycline?

Minocycline is a tetracycline antibiotic that fights off infection in the body. It is a broad-spectrum antibiotic that can be used to treat a range of different problems.

Minocycline is commonly prescribed to treat acne, as well as a number of infections.

It is sometimes sold under the brand name Minocin MR (modified release).

You cannot buy Minocycline unless you have been prescribed it by a doctor.

What is Minocycline used to treat?

Minocycline is often prescribed as a treatment for acne and other bacterial infections.

It can also be used in cases of sexually transmitted infections like gonorrhoea and syphilis, as well as common infections like bladder infections, skin infections and tick fever.

As an acne treatment, Minocycline works to kill the harmful bacteria that builds up on the skin. It should be taken for at least 6 weeks.

Minocycline has been described as one of the most effective acne medications available.

What causes acne?

Acne is a very common skin condition that can affect people of all ages. It occurs when excessive amounts of an oily substance released by the sebaceous glands (sebum) and dead skin cells build up on the skin. This allows bacteria to grow on the skin’s surface. Waste products from the bacteria block the skin’s pores, which leads to redness and inflammation.

Acne is especially prominent in adolescents and young adults. It affects 95% of people aged between 11 and 30 to some extent.

How does Minocycline work?

Minocycline is a tetracycline antibiotic. It works by stopping the growth of the bacteria that causes acne.

It will help to kill P. acnes, which can build up in the pores and cause acne. By killing these bacteria, inflammation will also be reduced. Minocycline also has anti-inflammatory properties, meaning that it is able to alleviate redness and inflammation caused by acne.

Minocycline dose

The following doses may be recommended for adults to treat these conditions:


50mg twice a day for at least 6 weeks

Always take the dose that your doctor has prescribed you. Ask them if you are not sure how much to take.

How to take Minocycline

Take Minocycline while standing or sitting upright. Do not take it straight before bed or before lying down.

Swallow Minocycline tablets whole with a drink of water.

Do not take this medicine at the same time as food or any dairy products, as this may stop the medicine from being absorbed and make Minocycline less effective.

Minocycline must not be taken by children under 12 years of age.

Always read the patient information leaflet, which will come with your medicine, for full instructions.

Who can take Minocycline?

While Minocycline is generally safe to take, Minocycline may not be suitable for everyone.

Before your doctor gives you a prescription to use this medicine, you should let them know if you have any of these conditions:

  • Asthma or a sulphite allergy
  • Liver disease
  • Kidney disease

This medicine should not be used if you are pregnant. If you are currently pregnant, think you might be pregnant or are trying to get pregnant, you should inform your doctor. The medicine could harm your baby and possibly cause permanent tooth discolouration later in life.

Minocycline can influence how well birth control pills work, so you should speak to your doctor about using a non-hormonal contraceptive, such as spermicide, to help prevent pregnancy while taking Minocycline.

Similarly, this is not a suitable treatment for anyone who is currently breastfeeding.

Children should not take this medicine unless they have been specifically instructed to do so by their doctor. Do not give Minocycline to children under 12 years old.

Minocycline common side effects

Not everyone will suffer from side effects while taking Minocycline, but you should seek medical attention if you suffer from any of these reactions while taking the medicine:

  • Numbness or pins and needles
  • Hair loss
  • A headache
  • Feeling sick or loss of appetite
  • Diarrhoea
  • Dizziness or a spinning sensation
  • Discolouration of your nails or skin
  • A cough

Please note, this list is not exhaustive. For more serious side effects, please refer to the Side Effects tab on this page.

Always read the patient information leaflet thoroughly to see the full list of adverse effects you may experience.

This medicine may cause dizziness, so if you do suffer from this reaction to taking it, you are advised not to drive, ride a bike or operate any machinery until you have either consulted a doctor or the dizziness has completely subsided.

Can you buy Minocycline over the counter?

No, Minocycline is not for sale over the counter. You will need to have a prescription to be able to buy this from a pharmacy.

Can you buy Minocycline online in the UK?

You can buy Minocycline online from Medicine Direct, but you will first need to fill out an online consultation questionnaire. The answers you provide in this questionnaire will be reviewed by one of our doctors, pharmacists or prescribers, who will assess your condition to make sure that Minocycline is the right treatment for you.

To ensure you only order genuine and approved medication, never order any medicine online from anywhere but regulated pharmacies, like Medicine Direct. Full details on the organisations that regulate our company can be found on the About Us page.

Minocycline alternatives

Minocycline is the active ingredient contained in another treatment, Minocin, which is also prescribed to treat acne.

Alternative oral antibiotics for treating acne that are available to buy at Medicine Direct include:

Topical treatments for acne are also available, such as:

  • Acnecide
  • Duac gel
  • Zineryt lotion
  • Dalacin T lotion
  • Treclin gel

Minocycline Dosage

Always read the patient information leaflet thoroughly before you start to take Minocycline.

Take the medicine exactly as instructed by your doctor.

Our pharmacists and prescribers follow NICE guidelines when prescribing Minocycline.

How long will I need to take it for?

If you are taking Minocycline (Minocin MR) to treat acne, you will likely need to take it for a minimum of 8 weeks.

Your treatment will be assessed after 3 months, to see how effective Minocycline has been at treating your symptoms.

Depending on how effective the medication has been, you may be required to take Minocycline for up to 6 months.

Even if your symptoms begin to improve, you should not stop taking Minocycline (Minocin MR). Acne may flare up again if you cease taking the medication before your course of treatment is complete.

What if I take more than I should?

You should contact your doctor or pharmacist if you become worried or take more than one extra dose.

Never increase the dose of a prescribed medicine unless a doctor has instructed you to do so.

What if I forget to take it?

If you forget to take a dose, don't worry; just take it as soon as you remember. If it is nearly time for your next dose, you should skip the missed dose and just continue to take Minocycline as usual.

Never double dose a medicine in an attempt to make up for a missed dose.

To avoid taking too much Minocycline (Minocin MR) or forgetting to take it, you should try to take the dose at the same time every day; this will get you into a routine. Some people find it beneficial to set an alarm to remind them.

What is Minocycline used for?

Minocycline is primarily used to treat the signs and symptoms of Acne.

How long does Minocycline take to start working?

Typically, the benefits of tetracycline antibiotics will take around 6 weeks to take effect and start providing visible improvements to your acne.

What type of Acne does Minocycline treat?

Minocycline can clear most types of acne such as facial, back acne and hormonal acne. The bacteria responsible for causing acne is predominantly the same despite where acne appears on your body.

How long should I take Minocycline for?

You should not take Minocycline for more than 12 weeks (3 months).

What happens if Minocycline does not clear my acne?

You acne will usually be assessed at 6 weeks to see how your symptoms have responded to the treatment, If no improvement has occurred during that time, your doctor will likely discuss some alternative treatment options with you.

Will my acne come back if I stop using Minocycline?

It is possible that your acne can come back if you stop taking Minocycline, particularly if you stop your treatment prematurely. To receive the full benefits of the medicine you must complete your treatment length unless advised otherwise by your doctor.

Will Minocycline make my acne worse before it gets better?

Tetracycline antibiotics can sometimes cause a skin purge/breakout in acne within the first couple of weeks of starting your treatment. 

Does Minocycline cause any side effects?

Common side effects of Minocycline include, headaches, nausea, diarrhoea, numbness, dizziness, discoloration, cough, and hair loss.

Will Minocycline permanently cure my acne?

Minocycline needs to be taken consistently for at least 6 weeks to treat acne. While it does provide effective treatment for this condition, there is a risk that your acne may return after you stop treatment. If this does happen, speak to your doctor.

Why should you not eat dairy while taking Minocycline?

Dairy products, including milk, can stop Minocycline from being absorbed properly. This means that you will not receive the correct dose of medicine, which can hinder your treatment.

Can I drink alcohol whilst taking Minocycline?

Yes, it is safe to drink alcohol whilst taking Minocycline.

Minocycline Side Effects

The more common side effects of taking Minocycline (Minocin MR) can be found on the main page.

In rare cases, you may experience more serious side effects while taking this medication.

If you experience any of these symptoms, you should seek medical attention immediately:

  • Loss of appetite, stomach pain, nausea or vomiting, bruising, bleeding, dark urine, yellowing of the skin or whites of the eyes (these could be signs of liver or pancreas problems)
  • Severe headaches
  • Ringing of the ears
  • Dizziness
  • Vision problems
  • Pain behind the eyes
  • Swollen glands
  • Flu-like symptoms
  • A cough and fever
  • Inflammation of the pancreas
  • Inflammation of the bowel
  • Raised pressure within the skull

In some cases, you may suffer a severe allergic reaction to taking this medicine; if this happens, you may require immediate treatment in hospital.

Call 999 or go to A&E immediately if you have any of the following while using Minocycline (Minocin MR):

  • Difficulty speaking or breathing
  • Tightness in the chest or throat
  • A skin rash that is red, itchy, blistering, peeling or swollen
  • Swelling of the face, tongue, lips, mouth or throat
  • You are wheezing

Always read the patient information leaflet and the instructions on your prescription before you start to take any medicine, to limit the risk of side effects occurring.

Only purchase this medicine from a UK registered pharmacy like Medicine Direct.

Minocycline Warnings and drug interactions

Minocycline (Minocin MR) may interact with other drugs you are currently taking, whether they are to treat acne or another condition altogether.

You should always make sure you inform your doctor of any other medicines you are already taking before you use another medication. These include prescription and non-prescription medicines, vitamins, supplements and any herbal remedies.

Antibiotics may cause diarrhoea, which can sometimes be the sign of a new infection. If you have watery or bloody diarrhoea, you must speak to your doctor; do not use any anti-diarrhoea medicine unless advised to do so by your doctor.

This medicine can make you sunburn more easily, so you should wear sunscreen and cover your skin if you go out in the sun. You should also avoid using tanning beds.

For two hours before and after taking this medicine, you should avoid taking antacids, multivitamins, laxatives or any supplements that contain calcium, magnesium, or iron. Any of these medicines can make it more difficult for Minocycline to be absorbed into your body properly, thus making it harder for the drug to take effect properly.

Other drugs you should avoid while taking Minocycline include:

  • Blood thinners like Warfarin
  • Isotretinoin
  • Ergot medicines
  • Any antibiotics that contain Penicillin

This list is not exhaustive. You must always read the patient information leaflet, which will come with your medicine, for the full list of drugs that can interact with Minocycline.

If you have any concerns, questions or doubts at all, do not hesitate to ask your doctor or pharmacist for advice, before you start to take this medicine to treat acne or any other condition.

If you order Minocycline online, you should only do so from a registered online pharmacy like Medicine Direct. This will ensure the drugs you order are genuine and safe to use.

Preganancy and breastfeeding

Minocycline is not indicated for use during preganacy and breastfeeding due to the effects on infants. Always speak to your doctor if you are planning to become preganat or intend to breastfeed. Learn more about taking minocycline during preganacy and breastfeeding

Minocycline Ingredients

The main active ingredient within this medicine is: Minocycline hydrochloride

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
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Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Hussain Abdeh MPharm: 2211840

Updated on: 21/05/2021

Published on: 12/10/2020

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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  • 3 Receive your delivery Your medication is dispensed and delivered directly to you from our UK based Pharmacy.

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