Fybogel Mebeverine (Orange Flavour)

  • Very high in natural fibre
  • Helps to promote natural bowel movements
  • Relieves spasms and cramps in the gut
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What is Fybogel Mebeverine?

Fybogel Mebeverine is a medicine which contains ispaghula husk, a natural plant material that is very high in fibre.

The medicines comes as an orange-flavoured powder sachet, which should be mixed with water and drank.

Mebeverine is an anti-spasmodic medicine that helps to relax the stomach muscles. This makes this medicine an effective treatment for irritable bowel syndrome (IBS), helping to encourage bowel movements and relieve discomfort.

What is Fybogel Mebeverine used to treat?

Fybogel Mebeverine is used to treat constipation and irritable bowel syndrome.

This medicine contains two different active ingredients, a laxative and an antispasmodic, which means that it can both treat stomach pain and also help you to go to the toilet.

Fybogel Mebeverine is dissolved in water for a pleasant-tasting orange drink, which is also sugar and gluten-free.

How does Fybogel Mebeverine work?

This medicine works by increasing the bulk of the contents of your gut passing through the digestive system. This helps to promote normal bowel movements and relieves spasms and cramps that occur in your gut.

It contains two active ingredients, ispaghula husk and mebeverine. Ispaghula husk is a type of fibre known as a bulk-forming laxative, which helps to relieve constipation and maintain regular bowel movements. When mixed with water, it swells in the gut and increases the volume of your bowel movements without being absorbed into the body. The muscles of the bowel wall can then push the contents along, helping you to go to the toilet.

Mebeverine is an antispasmodic which relaxes the muscles in and around the intestinal wall, which relieves the abdominal pain that comes with spasms caused by irritable bowel syndrome.

How to take Fybogel Mebeverine

Adults and children over 12 years should take one sachet half an hour before eating breakfast, then a second one half an hour before the evening meal.

A third sachet can be taken at lunchtime if required.

Mix the contents of the sachet into a glass of approximately 150ml of cold water. Consume the whole drink straight away.

Aside from Fybogel Mebeverine, you should make sure you drink plenty of water throughout the day.

Do not take this medicine before you go to bed. Speak to your doctor if you have not noticed an improvement after two weeks.

Fybogel Mebeverine Possible side effects

As with all medications, Fybogel Mebeverine may cause certain adverse effects, although not everyone gets them.

Contact your doctor immediately if you experience a skin rash; symptoms may include itching or stinging.

For the first few days of using this medicine, you may experience flatulence or bloating; these symptoms should go away as your treatment progresses.

You may also have difficulty swallowing and/or a bowel blockage.

If any of these symptoms bother you or persist, you should speak to your doctor as soon as possible.

Please, refer to the Side Effects tab on this page for a list of rarer, more serious reactions you might experience.

Who can take Fybogel Mebeverine?

Fybogel is not suitable for children under 12 years old.

You should consult your doctor before taking Fybogel Mebeverine if:

  • You are vomiting
  • You are over the age of 40
  • You have severe constipation
  • You have pain or difficulty while passing urine
  • You have lost weight or lost your appetite
  • You have been prescribed potassium supplements
  • You have a fever
  • You have unexplained vaginal bleeding or vaginal discharge
  • You have been prescribed a potassium-sparing diuretic medicine
  • You have blood in your stools
  • You look pale or feel tired
  • You are pregnant, trying to get pregnant or are breastfeeding

This list is not exhaustive. Always read the patient information leaflet, which comes with your medicine, before you start to take it.

Can you buy Fybogel Mebeverine over the counter?

Yes, you can buy Fybogel Mebeverine over the counter from your local pharmacy.

Can you buy Fybogel Mebeverine online in the UK?

You can buy Fybogel Mebeverine online from Medicine Direct by filling out a simple questionnaire on our website. Your answers will be reviewed by one of our registered prescribers to make sure that this medicine is safe for you to use.

You can then order from our online pharmacy, with next day delivery if your order is placed by 2pm.

It is important to ensure that you are buying medicine online from a UK fully regulated pharmacy. To learn more about our company, team, medical professionals, and the licenses we hold, visit our about us page.

Fybogel Mebeverine alternatives

Various alternatives to Fybogel Mebeverine can be ordered from Medicine Direct. The full list of IBS treatment can be found on the Irritable Bowel Syndrome product page.

Peppermint oil capsules such as Apercap and Colpermin are available to order without needing a prescription. These capsules contain peppermint oil, which works to relax the muscles in the gut, relieving discomfort effectively. They can also regulate bowel movements, relieving bloating.

Senocalm IBS Relief works to ease stomach cramps and can also help to alleviate bloating.

Alverine Citrate is another muscle relaxant that can swiftly relieve irritable bowel syndrome symptoms. This medication is a prescription-only medicine (POM), but you can buy it from Medicine Direct after completing an online consultation questionnaire.

IBS is a condition that is usually lifelong, there is no cure for IBS, however certain diet changes can help with symptoms.

A study into a low-FODMAP diet found that the restriction of FODMAP's (fermentable oligo-, di-, mono-saccharides and polyols, which are essentially short term carbohydrates that are resistant to digestion) was effective at reducing IBS symptoms.

Fybogel Mebeverine Indications and Dose

Always read the patient information leaflet thoroughly before you start to take Fybogel Mebeverine. Make sure you follow your doctor's instructions on how to take this medication. Consult your doctor if you are unsure of how to take it.

Our pharmacists and prescribers follow NICE prescribing guidelines when prescribing Fybogel Mebeverine.

Adults and children over 12 years old should take Fybogel Mebeverine half an hour before they eat a meal. They should take one sachet in the morning and one in the evening, or as instructed by your doctor.

To take this medicine, stir the contents of one sachet into a glass of cold water (at least 150mg) and drink it immediately.

Avoid inhaling the powder while pouring it into the glass.

Do not take Fybogel Mebeverine without water or before you go to bed. Wait at least one hour before you take any other medicine. The effects of this treatment may take between 12 and 24 hours to relieve your symptoms.

What if I miss a dose?

If you miss a dose, just take the next dose at the scheduled time. Do not double dose to try and make up for missing a previous dose.

What if I take more than I should?

If you take too much, drink plenty of water to flush the extra medicine out of your system.

What is Fybogel Mebeverine used to treat?

Fybogel Mebeverine is used to treat the painful symptoms of IBS, it contains Fybogel which is a laxative that can help with the symptoms of constipation. It also contains Mebeverine which is an antispasmodic which helps to relieve the symptoms of painful muscle crams, bloating and abdominal pain.

Can I take Fybogel Mebeverine everyday?

Whilst it is safe to take every day, it is generally not recommended. You should only use Fybogel Mebeverine when symptoms start to flare up. Using a laxative daily can lead to diarrhoea over a prolonged period of time.

Is Fybogel Mebeverine a Laxative?

Yes, one of the active ingredients (Fybogel) in this medicine is classed as a laxative.

What is the difference between Fybogel and Fybogel Mebeverine?

Fybogel just contains the active ingredient Fybogel which is a laxative. Fybogel Mebeverine contains both Fybogel and Mebeverine which is an antispasmodic and helps to relieve painful IBS symptoms such as stomach cramps, bloating and abdominal pain.

What are the side effects of Fybogel Mebeverine?

Common side effects include flatulence and bloating, however these symptoms should go after a few days. 

When is the best time to take Fybogel Mebeverine?

You should take Fybogel Mebeverine 30 minutes before each one of your 3 main meals.

Can I drink alcohol whilst using Fybogel Mebeverine?

Yes, it is safe to drink alcohol whilst using this medicine. However alcohol can trigger a number of IBS symptoms even when taking Fybogel Mebeverine.

Fybogel Mebeverine Side effects

It is possible to suffer a mild allergic reaction while taking Fybogel Mebeverine. Stop taking this medicine and speak to your doctor or pharmacist for advice if you think this is happening to you.

In rare cases, you could experience a serious allergic reaction to Fybogel Mebeverine, or any of its ingredients, and require immediate treatment in hospital.

You should either go to A&E or dial 999 straight away if you experience any of the following symptoms:

  • You have a skin rash that is red, itchy, swollen, blistered, or peeling skin
  • You have swelling in your throat, mouth, face, lips, or tongue
  • You are wheezing
  • You have tightness in your chest or throat
  • You are finding it difficult to breathe or speak

This list might not be exhaustive. Always read the patient information leaflet thoroughly before you start to use this medicine.

Fybogel Mebeverine Warnings and drug interactions

Fybogel Mebeverine can interact with other medicines and increase your risk of side effects or hinder the medicine's effectiveness.

Always ensure you tell your doctor if you are taking any other medicines before you start using another one. This includes both prescription and non-prescription medications, vitamins, supplements and herbal remedies.

In particular, you should inform your doctor if you are already taking any of the following:

  • Carbamazepine to treat mood problems and epilepsy
  • The heart medicine digoxin
  • Mesalazine, which is used to treat gut problems

Read the patient information leaflet thoroughly before you start to take this medicine.

If you have any questions or concerns at all, we strongly advise you to discuss these with your doctor, before you start to use Fybogel Mebeverine.

Never order medicine online unless it is from a pharmacy registered with the General Pharmaceutical Council, like Medicine Direct.

If you order with us, we promise you only genuine medicine and if you order before 2pm, we can offer you next day delivery on your purchase.

Pregnancy and breastfeeding

Fybogel Mebeverine is generally safe to use during pregnancy and breastfeeding.

Ask you doctor about taking any medicines if you are pregnant or breastfeeding.

For more information on taking Fybogel mebeverine and treating constipation when pregnant or breastfeeding.

Fybogel Mebeverine Ingredients


The main active ingredients within this medicine are: Ispaghula husk and Mebeverine hydrochloride

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Hussain Abdeh MPharm: 2211840

Published on: 12/10/2020

Updated on: 18/08/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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