Lymecycline Capsules (408mg)

  • Effective in the treatment of Acne
  • Reduces redness and inflammation of the skin
  • Prevents skin pores from clogging

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There is no quick fix when it comes to treating acne, it can have a huge impact on self-confidence, quality of life and has also been linked to depression. Fortunately, Acne can be treated with Lymecycline, which kills the bacteria responsible for causing acne.

What is Lymecycline?

Lymecycline is a tetracycline broad-spectrum antibiotic that is primarily used in the treatment of acne.

Lymecycline helps to kill and stop the spread of bacteria responsible for causing acne on the skin. It does this by starving them of essential proteins that they need to survive.

Lymecycline comes as a capsule that you swallow and is a prescription-only medicine (POM) for adults and children aged 12 and above.

What is Lymecycline used to treat?

Lymecycline tablets are used as a treatment for various infections, but they are predominantly used in the treatment of acne. The antibiotic works by reducing the redness and inflammation which occurs during acne breakouts, but it also prevents the skin's pores from clogging.

It is often sold under the brand name Tetralysal.

Lymecycline is a widely prescribed treatment for acne, although it may take up to 8 weeks before your acne clears.

How does Lymecycline work?

Lymecycline belongs to the tetracycline class of antibiotics. It works to kill the bacteria that causes spots and pimples by preventing them from being able to create the proteins they need to survive and reproduce.

The bacteria, known as propionibacterium acnes, are responsible for a number of infections although they are predominantly known for their role in acne. 

P. acnes specifically feed on sebum, which is a naturally occurring oil produced by the sebaceous glands in the skin. However, when feeding on sebum causes the sebaceous glands to become inflamed causing redness, swelling and spots on the surface of the skin.

By killing and reducing the volume of bacteria present on the skin, the inflammation caused by the bacteria is decreased, thus improving the appearance of acne symptoms.

While it may take several weeks until your acne has cleared, you should start to notice an improvement within one week of taking Lymecycline.

Lymecycline dose

The usual dose of Lymecycline for treating acne is to:

Acne 1 x 408mg capsule daily for 8 weeks

The dosage may vary if you have been prescribed Lymecycline to treat a different type of infection. If this is the case, follow the instructions of your doctor.

How to take Lymecycline

Swallow one capsule whole with a glass of water. Do not crush or chew the capsule.

Lymecycline can be taken with or without food, although you are less likely to experience nausea if you take it with food.

Keep taking Lymecycline until your course of treatment is completed, even if you notice an improvement or feel better. Prematurely stopping treatment may make the problem return.

Always read the patient information leaflet for comprehensive instructions. Ask your doctor or pharmacist if you are not sure.

Lymecycline Common Side Effects

As is the case with all medicines, Lymecycline comes with the risk of certain side effects.

If you are using this medicine, common side effects include:

  • Feeling sick
  • Headaches or visual disturbances
  • Diarrhoea
  • Stomach pain

This list is not exhaustive; for the full list of undesired effects, please refer to our Side Effects tab on this page.

If you experience any of the above reactions, keep taking the medicine to treat your acne, but inform your doctor if these symptoms persist or bother you.

Please also refer to the patient information leaflet to familiarise yourself with the common and more adverse side effects.

Who can take Lymecycline?

Lymecycline is an effective treatment for acne, but it may not be suitable for everyone.

This medicine is safe to be taken by adults and children over 12 years old.

It is not normally recommended for women who are pregnant or breastfeeding. If you are pregnant, trying to get pregnant or are breastfeeding, you should consult your doctor before taking Lymecycline as there may be a more suitable treatment for you.

To ensure that Lymecycline is safe for you to use, you should inform your doctor if you:

  • Have liver problems
  • Have kidney problems
  • Have ever had an allergic reaction to Lymecycline or any other medicine in the past
  • Have an autoimmune disease called lupus
  • Have the muscle-weakening condition myasthenia gravis

When on a course of Lymecycline, alcohol will not affect the benefits of this medicine when consumed in moderation.

Can you buy Lymecycline over the counter?

No, Lymecycline is only available to buy when you have been prescribed it by a doctor.

Can you buy Lymecycline online in the UK?

Yes, you can buy Lymecycline online in the UK, but you should not order from anywhere other than regulated pharmacies, like Medicine Direct. Full details of who we are regulated by can be found on the About Us page.

As Lymecycline is a prescription-only medicine (POM), you must first complete an online consultation form. This is so one of our doctors, pharmacists or prescribers can review your answers to ensure that Lymecycline is safe and suitable for your condition.

Lymecycline alternatives

The branded version of Lymecycline, Tetralysal, can also be ordered from Medicine Direct after an online consultation.

Additionally, we stock various other medication that is widely prescribed for effective acne treatment. Alternative oral medicines available include Erythromycin and Minocycline.

Topical treatments like Acnecide, Duac gel or Dalacin T lotion are also available.

Visit the Acne page on our website to view the full range of treatments we stock.

Lymecycline Dosage

Our pharmacists and prescribers follow NICE prescribing guidelines when prescribing Lymecycline.

You should always make sure you read the patient information leaflet thoroughly before taking any medication. Check with your doctor or pharmacist if you are unsure.

As an acne treatment, the patient should take one tablet each day. You will usually be recommended to take this tablet in the morning.

Lymecycline should be swallowed whole with a glass of water.

The medicine can be taken with or without food, but if you do take it with food you are less likely to feel sick afterwards.

Your doctor will usually review your progression after 8 weeks of taking the medicine.

What if I forget to take it?

If you forget to take this medicine, just take the dose as soon as you remember, as long as it is not too close your next scheduled dose. Do not double dose to try and make up for a missed dose.

You can improve your chances of remembering to take your treatment by taking it at the same time every day.

What if I take more than I should have?

Taking an additional dose of Lymecycline is unlikely to do you any harm.

You should contact your doctor if you take more than one extra dose or you become concerned.

Lymecycline FAQ's

How long does it take for Lymecycline to work?


Lymecycline will start to improve the symptoms of acne within 8 weeks, however; in some cases improvements may be seen within 1 week after starting treatment.

How long can I take Lymecycline for?


Lymecycline is typically prescribed for 8 weeks, however this can be extended depending on how your body and your acne symptoms respond to the treatment.

Will Lymecycline stain my teeth?


Lymecycline can cause discoloration on developing teeth, for this reason it is not recommended for anyone below the age of 12.

What happens if it does not clear my acne?


You doctor will usually assess your symptoms after 6 weeks of treatment. If there has been no improvement during this time, it is likely that your doctor will advise you to discontinue Lymecycline and will discuss other treatments option.

Is Lymecycline an antibiotic?


Yes, Lymecycline is an antibiotic, specifically belonging to the tetracycline broad spectrum family of antibiotics.

Will my acne come back if I stop taking Lymecycline?


There is more chance of your acne returning if you stop taking Lymecycline prematurely. You should finish your full course of antibiotics even if your symptoms improve during this time.

Will Lymecycline make my acne worse before it gets better?


Lymecycline works slowly, it is possible that after starting treatment your acne could get slightly worse. However it is important to persist with your treatment which should start to visibly reduce your acne within 8 weeks.

Can I use Lymecycline for Rosacea?


Lymecycline is not indicated as a first line treatment option for Rosacea. It is likely that there are more suitable alternatives for the treatment of rosacea.

Does Lymecycline help with Hormonal Acne?


Lymecycline should help to treat hormonal acne as the bacteria responsible for acne is largely the same.

Will Lymecycline cause my skin to breakout?


It is possible within the first 2 weeks of your treatment that Lymecycline may cause a break out. As the acne causing bacteria is decreased other cells on the surface of the skin can increase in volume which can sometimes cause a little bit of irritation, particularly early in the treatment cycle.

Will Lymecycline cause any side effects?


Common side effects of Lymecycline include, nausea, headaches, diarrhoea and stomach cramps. The side effects will begin to ease after a couple of weeks as your body gets used to the treatment.

Can I drink alcohol when taking Lymecycline?


Yes, you can drink alcohol whilst taking Lymecycline.

Lymecycline Serious Side Effects

It is not uncommon to experience side effects as a result of taking this medicine; the most common adverse effects can be found on the main product details tab.

In rarer cases, it is possible you may suffer from more serious adverse effects of this drug.

If you notice any of the following symptoms, you should stop taking the medicine immediately and consult your doctor:

  • Pale stools
  • Your skin becomes very sensitive to sunlight
  • Dark urine
  • Yellowing of the skin or the whites of your eyes (this can be a sign of liver problems)

In some cases, you may suffer a severe allergic reaction to Lymecycline.

If any of the below symptoms occur, you should stop taking the medication and either call 999 or go to A&E immediately; you may require treatment in hospital:

  • You find it difficult to speak or breathe
  • You develop a skin rash that is red, itchy, swollen, peeling or blistering
  • Your face, lips, tongue, mouth or throat starts to swell
  • You are wheezing
  • You have a tightness in your chest or throat.

This list is not exhaustive. You should always read the patient information leaflet thoroughly before you start taking any form of medication.

You should never take this medicine without a prescription.

Lymecycline Warnings and drug interactions

Lymecycline may not react well with other drugs. You should let your doctor know if you are currently taking any of the below medications before you start using Lymecycline:

  • Remedies for indigestion (antacids)
  • Medicines to treat epilepsy (for example phenytoin or carbamazepine)
  • Iron supplements
  • Quinapril, a medicine for high blood pressure or heart failure
  • Warfarin or any other blood thinning medicines
  • Diuretic tablets to make you urinate more
  • Any acne medicines that contain vitamin A
  • Supplements which contain aluminium, bismuth, calcium, magnesium or zinc

It is important that you inform your doctor and pharmacist if you are currently taking any other medication. This includes prescription and non-prescription medicines, supplements, vitamins and herbal remedies.

There are no known risks associated with taking Lymecycline with supplements, but you should make sure you inform your doctor if you are currently taking any supplements that contain either aluminium, bismuth, calcium, magnesium or zinc.

For more information on medicines that interact with Lymecyline Capsules.

Do not take Lymecycline unless your doctor has given you a prescription for it. Only order it online if it is from a UK registered pharmacy, such as Medicine Direct.

Pregnancy and breastfeeding

Tetracyclines such as Lymecycline are not usually prescribed to women who are pregnant or breastfeeding. Your should always inform your doctor if you are planning to become pregnant while taking Lymecycline. 

Your doctor will assess your condition and weigh the benefits against the risks of you taking Lymecycline during pregnacy and breastfeeding

Lymecycline Ingredients

The main active ingredient within this medicine is: Lymecycline

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

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Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Hussain Abdeh MPharm: 2211840

Published on: 12/10/2020

Updated on: 23/08/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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