Mirvaso Gel 30g

  • Topical gel containing Brimonidine
  • Reduces redness and flushing of the skin
  • Long-term daily treatment
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What is Mirvaso Gel?

Mirvaso gel contains the active ingredient Brimonidine, which is indicated in the treatment of facial erythema of Rosacea. It is very fast acting and can reduce symptoms over a sustained 12-hour period once applied to the skin.

Brimonidine belongs to a group of medicines known as alpha adrenergic agonists, specifically targeting the alpha 2 receptor. It possesses highly effective vasoconstriction properties which causes visible blood vessels on the face to constrict and reduce, suppressing some of the main symptoms of Rosacea.

Brimonidine (Mirvaso Gel) when used alongside lifestyle changes, such as avoiding rosacea triggers, can be highly effective at managing the symptoms of facial erythema of rosacea.

It can be used by adults over the age of 18 years old.

What is Facial Erythema of Rosacea?

Facial erythema is a subtype of rosacea and can cause the following symptoms:

  • Facial flushing
  • Dilated or broken blood vessels
  • Burning or stinging
  • Papules or pustules

Historically, treatment for facial erythema of rosacea consisted of a number of lifestyle changes including the application of high factor sunscreen, avoiding triggers such as extreme weather stress, exercise, spicy food, alcohol and hot drinks.

Brimonidine is the first medicine to be approved for the treatment of facial erythema of rosacea.

How does Mirvaso Gel work?

Brimonidine works to reduce the appearance of blood vessels visible on the upper dermis layer of the skin. It does this by restricting them, causing them to dilate and reduce in size. Mirvaso gel also possesses anti-inflammatory properties, redness and swelling of the skin is also visibly reduced as a result.

In summary, when applied to the skin, Mirvaso works to narrow the blood vessels back to their normal size, reducing visible redness and inflammation of the skin surrounding the affected area.

How do you apply Mivaso Gel?

Mirvaso gel should only be applied once every 24 hours.

Begin by applying a pea-sized amount of gel to the five key areas of the face:

  • forehead
  • nose
  • chin
  • both cheeks

Avoid contact with the eyes, eyelids, and lips.

Spread a thin layer of the gel smoothly and evenly across the skin. Do not exceed the daily dose of 1 gram, which is the equivalent to five pea-sized amounts applied to the entire face.

You should use your fingertips to apply the cream, once you have applied Mirvaso to the skin, wash your hands immediately.

Always use Mirvaso Gel exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly and ask your doctor or pharmacist for further instructions if you are still unsure how to use it.

Do not apply any other skin treatments or cosmetics directly before applying Mirvaso Gel. Only apply other skin products once this gel has dried.

Who should not use Mirvaso Gel?

Mirvaso Gel is not suitable for everyone to use. Before using this medicine, we recommend thoroughly reading the patient information leaflet for advice on who this treatment is suitable for.

Do not use this medicine if:

  • You are allergic to brimonidine or any of the other ingredients contained in the gel (please refer to the ingredients tab for a comprehensive list)
  • You are taking certain medications for Parkinson's disease or depression (please refer to the Warnings tab for further information)

This medicine is not suitable for people under 18 years old. This is particularly important in children under the age of 2; they may be at larger risks of side effects from any medicine that is absorbed through the skin.

You should make sure you talk to your doctor or pharmacist before using Mirvaso Gel if:

  • You have any circulation or heart problems
  • You have depression, a decreased blood flow to the brain or heart, a fall in blood pressure when you stand up, decreased blood flowing to the skin, hands, or feet, or Sjogren's syndrome
  • You have or have ever had any liver or kidney problems
  • You have had or are planning to have any laser procedure on the surface of the skin on your face
  • Your face's skin is irritated or has any open wounds

Common Mirvaso Gel side effects

Like all medicines, Mirvaso Gel does come with the risk of side effects, although not everyone will suffer from them.

Common side effects of Mirvaso Gel include:

  • Flushing
  • Skin redness or a burning/itching feeling

Uncommon side effects may include:

  • Acne
  • Headache
  • Nasal congestion
  • Cold feeling in the hands and feet
  • Swelling of the eyelid
  • Urticaria
  • Dizziness
  • Dry mouth
  • Feeling hot

Speak to your doctor if any of these reactions bother you or do not go away.

These lists are not exhaustive. Please refer to the Side Effects tab for more information. For a full, exhaustive list, please thoroughly read the patient information leaflet before using this medicine.

Mirvaso gel is cosidered safe to use in the long term treatment of facial erythema of rosacea. It continues to provide long term relief of symptoms when used consistently and applied as instructed.

Should you experience any side effects, it is important that you speak to your pharmacist or doctorwho may advise you to persist with your treatment plan, or discontinue depending on the severity of your side effects.

Mirvaso gel alternatives

There are a number of rosacea treatments available to help reduce some of the visible symptoms. However, when it comes to facial erythema of rosacea, Mirvaso gel is the first and only indicated treatment.

Other commonly prescribed rosacea treatments include:

Mirvaso Gel and Lifestyle changes

Whilst mirvaso gel can help to reduce some of the visible symptoms caused by rosacea, it should be considered as a treatment rather than a cure.

In order to successfully manage the symptoms of rosacea, certain lifestyle changes need to be adopted in conjunction with applying Mirvaso gel. Avoiding common trigger factors such as the below can help to manage rosacea symptoms more effectively:

  • Alcohol
  • Spicy foods
  • Hot drinks
  • Extreme weather
  • Strenuous exercise

How to apply Mirvaso Gel

Our pharmacists and prescribers follow NICE prescribing guidelines when prescribing Mirvaso Gel.

Storage and disposal

Keep Mirvaso Gel out of the sight and reach of children.

This medicine does not require any special storage conditions, but do not freeze it.

Do not use past the expiry date, which can be found on the packaging.

Do not dispose via wastewater or household waste. Speak to your doctor or pharmacist about how to safely dispose of any excess gel. This will help to protect the environment.

What is Mirvaso Gel used for?

Mirvaso gel is the first approved treatment specifically for reducing the symptoms caused by facial erythema of Rosacea. 

How does Mirvaso gel work?

The active ingredient Brimonidine constricts visible blood vessels that appear near the surface of the skin. As a result of this, it also reduces the swelling and redness caused by the inflamed blood vessel, thus reducing the appearance of facial erythema of rosacea.

Can mirvaso make my Rosacea worse?

Mirvaso gel can make Rosacea symptoms worse in approximately 4-15% of patients, particularly within the first week of using the treatment. Side effects such as worsening facial erythema and flushing tended to clear within 4-24 hours of discontinuing.

How long does it take for Mirvaso to work?

Mirvaso gel is rapid acting and has been shown to reduce symptoms over a sustained 12 hour period once applied. How long it will take to work will vary depending on the severity of your condition and how often you come into contact with your rosacea triggers.

Is Mirvaso gel safe to use for a long time?

Yes, Mirvaso gel is safe to use for a long time and continues to provide effective relief of symptoms for moderate to severe facial erythema of rosacea. Results are based on a 1 year study of Brimonidine.

When should I stop using Mirvaso?

You should not stop using Mirvaso unless instructed to do so by your doctor. You are unlikely to see the full benefits of your treatment if you stop it early. In cases of irritation, heat, itchiness or a rash, you should discontinue treatment of Mirvaso gel.

Will my rosacea return if I stop using it?

Yes, it is likely that your rosacea will return as normal if you discontinue mirvaso. Do not stop treatment unless advised by your doctor.

When should I use Mirvaso?

You should apply Mirvaso once daily. It is best to apply the cream at the same time every day.

Will mirvaso completely clear my Rosacea?

Mirvaso will help with rosacea symptoms, however it will not stop your rosacea from flaring up when coming into contact with a known trigger. You should adopt other lifestyle changes in order to prevent coming into contact with your known rosacea triggers.

Can I buy Mivaso over the counter in the UK?

Mirvaso is not available to buy over the counter, this treatment needs to be prescribed by a doctor or qualified pharmacist.

Can I buy Mirvaso Gel online in the UK?

Yes, you can buy mirvaso gel online from most UK online pharmacies such as Medicine Direct. You will be required to complete an online consultation with a UK prescriber who will assess your condition.

Mirvaso Gel Side Effects

Rare side effects of Mirvaso Gel can include:

  • Hypotension
  • A slow heart rate

Serious allergic reaction

In rare cases, it is possible that you might suffer a serious allergic reaction to Mirvaso.

You must either go to A&E or call 999 straight away if you get any of the following symptoms:

  • You are finding it hard to breathe or speak
  • You develop a skin rash that may include red, itchy, swollen, blistered or peeling skin
  • Your mouth, tongue, throat, lips or face starts to swell
  • You are wheezing
  • You have tightness in your chest or throat

You could be having a serious allergic reaction and require treatment in hospital immediately.

Always read the patient information leaflet for full details on side effects and how to cope with them. If you have any questions or concerns at all, please do not hesitate to talk to your doctor or pharmacist.

Mirvaso Gel Warnings

Seek medical attention immediately if anyone swallows any of this gel.

This medicine is not suitable for anyone under 18.

Mirvaso with other medicines

Before you start using Mirvaso Gel, please tell your doctor or pharmacist if you are already using any other form medicine, whether it is to treat rosacea or a different condition. This includes prescription and non-prescription medication, herbal remedies, vitamins and supplements.

Particularly, tell them if you are taking any of the following:

  • Medicines used for pain, sleep disorders or anxiety disorders
  • Any other alpha agonist medicines, alpha antagonists or alpha blockers
  • Medicines used to lower blood pressure, such as beta blockers
  • Medicines used for psychiatric disorders, high blood pressure or hyperactivity
  • Cardiac glycoside medicines

Do not use any of the following medicines alongside Mirvaso Gel:

  • Selegiline
  • Moclobemide
  • Imipramine
  • Mianserin
  • Maprotiline

For more information on medicicines that interact with Mirvaso Gel.

Alcohol and driving

Please ensure you inform your doctor if you drink alcohol on a regular basis. This may affect your treatment with Mirvaso Gel.

Mirvaso will not directly impair your ability to drive. However, one of the side effects of this medicine is dizziness; if you experience this while using Mirvaso Gel, you should not drive, cycle or operate machinery until you feel better.

Always read the patient information leaflet for complete details on warnings and drug interactions. Speak to your doctor or pharmacist before using Mirvaso Gel if you have any questions or concerns.

Pregnancy and breastfeeding

Mirvaso is not recommended for use by pregnant women, as the effects on the unborn baby are unknown.

It is also not known whether this medicine passes into your breast milk, so you are advised not to use Mirvaso Gel while breastfeeding, too.

Always read the patient information leaflet for full details on who may not be suitable to use this medicine.

Mirvaso Gel Ingredients

The main active ingredient within this medicine is: Brimonidine tartrate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Updated on: 16/08/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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