Rozex 0.75% Gel

  • Topical Metronidazole antibiotic gel
  • Treats mild to moderate rosacea
  • Reduces inflammation
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What is Rozex 0.75% (Metronidazole) Gel?

Rozex 0.75% gel is a topical treatment that is used to treat the skin condition rosacea. It works to treat the pimples, spots, and redness that this skin condition can cause.

Rozex is applied to the face, it contains the antibiotic Metronidazole. The gel and cream form of Metronidazole, is typically used to treat a number of skin infections, such as Rosacea.

What is Rozex (Metronidazole) Gel used to treat?

This topical medication is used to treat the chronic skin condition rosacea. This condition most commonly affects the cheeks, nose, chin, forehead, and eyelids. Rosacea manifests itself mainly through redness, pustules, and pimples.

Rozex is an effective medication when used to treat mild to moderate rosacea conditions. To effectively treat this skin condition, it should be applied twice a day for several weeks. To see the full benefits of Rozex 0.75% gel, you will need to keep applying it for at least three months.

How does Rozex treat Rosacea?

Rozex 0.75% gel contains the active ingredient metronidazole, which belongs to a group of medicines known antibiotics and antiprotozoal. This ingredient works by stopping the growth of bacteria and parasites responsible for causing infections.

Although it is not fully understood how metronidazole works to successfully treat rosacea, studies have found that Rozex (Metronidazole) 0.75% gel reduced papules and pustules on the skin by between 48% to 65.1% during a 12 week period.

Topical metronidazole 0.75% can prevent a relapse of moderate to severe rosacea in patients over a 6 month period.

How to use Rozex

Apply Rozex 0.75 gel as your doctor or pharmacist has told you to. Read the patient information leaflet and speak to your doctor or pharmacist if you are not sure.

Our pharmacist and prescribers follow NICE prescribing guidelines when prescribing Rozex Gel.

Your doctor or pharmacist will tell you how long you will need to apply Rozex gel to treat your case of rosacea.

Use this gel twice a day (once in the morning, once in the evening), unless your doctor or pharmacist tells you to do otherwise.

Do not get it in your eyes. If any of this medicine does get into your eyes, rinse them immediately with plenty of warm, clean water.

Application Directions

  1. Wash and dry the affected areas of skin.
  2. Apply a thin layer of the gel to the affected areas, avoiding contact with the eyes.
  3. Gently Rub the gel into the skin.
  4. After use, replace the cap and wash your hands.

Rozex (Metronidazole) Alternatives

There are a number of treatments that have been compared to the effectiveness of Rozex Metronidazole 0.75% gel, most notably Soolantra (Ivermectin) cream

Studies have found that Soolantra cream is superior to Metronidazole Gel when reducing inflammatory skin lesions. Users reported 10% fewer lesions when using Soolantra over a 16-week period.

Other alternatives include:

Non-medicine alternatives

However, the following non-medical lifestyle changes can help to control or improve your symptoms:

  • Cleanse your face with a rosacea friendly soap
  • Regularly moisturise
  • Always wear sun cream on the affected area
  • Use skin friendly cosmetic products free from alcohol, parabens and other harmful ingredients
  • Be gentle with your skin, do not scrub or exfoliate your skin

For more information, visit the American Academy of Dermatology Association.

Who can use Rozex Gel?

Rozex is not a suitable medicine for everyone to use.

It is not a suitable medicine for children.

Do not use Rozex if you are allergic to metronidazole or any of the other ingredients contained in this medicine (please refer to the ingredients tab for a full list of substances).

Speak to your doctor or pharmacist before using Rozex gel if you suffer from any blood disorders.

Full details on why this medicine may not be suitable for can be found in the patient information leaflet, which will come with your order. Talk to your doctor or pharmacist if you have any questions or concerns.

Possible side effects

Like all medicines, Rozex 0.75% gel can cause side effects, although not everyone will get them.

Common side effects may occur in up to 1 in 10 people using this medicine:

  • Skin irritation
  • Pruritus (itching)
  • Dry skin
  • Worsening of rosacea
  • Redness of the skin
  • Skin discomfort, such as pain, stinging or burning

Uncommon side effects may occur in up to 1 in 100 people applying it:

  • Metallic taste
  • Feeling sick
  • Numbness and tingling in the fingers and toes

Please note, this list is not exhaustive. Please refer to the Side Effects tab for a list of rarer and more serious side effects.

Can you buy Rozex 0.75% Gel online?

Rozex 0.75% gel can be bought online from most UK Online Pharmacies such as Medicine Direct. Rozex is a prescription only medicine, so an online health consultation will need to be completed with a doctor or healthcare professional so your condition can be fully assessed. In some cases, our medical professionals may wish to see a picture of the affected area, so they can ensure that Rozex is the most suitable treatment for your condition.

It is important to ensure that you are buying medicine online from a UK fully regulated pharmacy. To learn more about our company, team, medical professionals, and the licenses we hold, visit our about us page.

Rozex 0.75% Gel indications and Dose

Rozex Gel Indications and Dose
Inflammatory papules, pustules and erythema of Rosacea Apply twice daily for 3-4 months
Source NICE

If you use too much or swallow the gel

Rozex gel is for external use only; do not swallow any of the gel. Speak to your doctor straight away if you or anybody else accidentally swallows the gel. If you apply too much and suffer any side effects, speak to your doctor or pharmacist.

If you forget to use it

If you miss an application or Rozex, apply it at your next scheduled time. You need to be using Rozex consistently to effectively treat rosacea. To ensure you do not forget to apply this treatment, try to apply it at the same times every day. Some people find it helps to set an alarm as a reminder.

Do not apply a double dose to try and make up for forgetting to apply it earlier.

If you stop using Rozex

It will take a few months before you will notice the full benefits of this medication. You must keep using Rozex until your doctor or pharmacist tells you to stop applying it.

What is Rozex gel used for?

Rozex is used to treat mild to moderate rosacea on the face. Rozex is effective at reducing papules, pastules, pimples, redness and inflammation of the skin on the face.

How does Rozex gel work?

Metronidazole works by stopping the growth and spread of bacteria that is present on the skin, thus helping to reduce the symptoms of rosacea on the face.

How long does Rozex gel take to work?

Studies conducted have found that Rozex successfully reduced papules and pustules of the skin by 48-65.1% during a 12 week period. To effectively treat the signs and symptoms of rosacea, rozex should be used for at least 3 months.

How should I apply Rozex gel?

Before application, you should wash and gently dry the affected area of the skin. Apply a thin layer to the affected area, ensuring that you avoid contact with the eyes. Gently rub the gel into the affected area and leave to dry naturally. Wash your hands after use.

How long will I need to take Rozex for?

Your duration of treatment is subject to the severity of your condition and how well you react to Rozex. Typically you will be prescribed Rozex for a minimum of 3 months. 

Is Rozex safe to use for a long time?

Long term use of antibiotics such as Metronidazole is not recommended, however; using the antibiotic is a topical (gel or cream) form is recommended if used for a long period of time. Long term use of metronidazole has been shown to prevent a relapse in moderate to severe rosacea.

Will my Rosacea return if I stop using it?

It is possible that you may suffer a relapse of rosacea symptoms when stopping treatment. Do not stop treatment unless advised to by your doctor. 

How often should I apply Rozex?

You should apply this gel twice daily, ideally in the morning and evening.

Can I go out in direct sunlight whilst using rozex?

Using rozex is likely to cause heightened sensitivity to direct sunlight. It is recommended to apply a sun block specifically for sensitive skin that will provide you with adequate protection from UV rays that may irritate your skin and make symptoms worse.

Is Rozex Gel an antibiotic?

Rozex contains metronidazole, when used as a topical treatment Metronidazole falls into the nitroimidazole antimicrobials class of drugs.

Is Rozex gel safe to use during pregnancy or breastfeeding?

It is generally considered safe to use Metronidazole during pregnancy. If you are breastfeeding it is important not to apply this to your breasts.

How much is Rozex gel to buy in the UK?

Prices start at £21.99 for 1 tube, you can buy a maximum of 4 tubes.

Rozex 0.75% Gel Side Effects

A list of common side effects can be found on the main product page.

The following side effects may occur at an unknown frequency:

  • Skin peeling
  • Contact dermatitis
  • Facial swelling

Speak to your doctor if any of these side effects persist.

Serious allergic reaction

In rare cases, it is possible that you may suffer a serious allergic reaction to Rozex.

You must either go to A&E or call 999 straight away if you notice any of the following side effects:

  • Your mouth, face, lips, throat or tongue starts to swell
  • You are finding it difficult to speak or breathe
  • You are wheezing
  • You get a skin rash that may include red, itchy, swollen, blistered or peeling skin
  • You have tightness in your chest or throat

You could be having a serious allergic reaction and require immediate treatment in hospital.

Always read the patient information leaflet for a complete list of side effects, as well as advice on how to deal with them. Speak to your doctor or pharmacist if you are worried about side effects or have any questions.

Rozex 0.75% Gel Warnings

Rozex contains methyl parahydroxybenzoate and propyl parahydroxybenzoate, which may cause allergic reactions. These reactions may be delayed. Please refer to the Side Effects tab for symptoms of an allergic reaction.

Always ensure you are not taking any medicines that interact with Rozex Gel.

It also contains propylene glycol, which may cause skin irritation.

This product is not suitable for children and should not be used by them.

Do not keep applying Rozex for longer than your doctor or pharmacist has instructed you to.

Avoid exposure to strong sunlight, such as sunbathing, and ultra-violet light (e.g. sunbeds) while you use this medicine.

Drug interactions

Before you start to apply Rozex, you must tell your doctor or pharmacist if you are already taking any other prescription or non-prescription medication. This includes herbal remedies, vitamins and supplements.

In particular, tell them if you are taking any blood thinning medicines (anticoagulants), such as warfarin. Rozex may interact with these drugs and stop them from working properly. If you suffer from any blood disorders or are taking any medicines to thin your blood, please talk to your doctor or pharmacist before starting your course of treatment with Rozex.

Rozex and alcohol

Metronidazole can react to alcohol, so you are advised to avoid drinking alcohol while applying Rozex.

For complete information on warnings and drug interactions to be aware of with Rozex, please read the patient information leaflet. If you have any questions or concerns, please talk to your doctor or pharmacist before you start your course of treatment.

Applying Rozex Gel when pregnant or breastfeeding

Rozex may not be suitable for you to use if you are pregnant, although your doctor or pharmacist will determine this based on your specific case of rosacea. 

For more information on using Rozex Gel during pregnancy and breastfeeding.

Talk to your doctor or pharmacist before using Rozex if you are pregnant or breastfeeding, or if you think you might be pregnant or are trying to get pregnant.

Rozex 0.75% Gel Ingredients

The main active ingredient within this medicine is: Metronidazole

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Medically reviewed byHussain Abdeh MPharm: 2211840

Updated on: 01/07/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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