- Lowers the bodies production of bad cholesterol
- Lowers the risk of heart problems such as heart disease, heart attacks as well as strokes
- Lipid-lowering medication that belongs to the statins class of drugs
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What is Simvastatin?
Simvastatin is a lipid-lowering medication that belongs to the statins class of drugs.
It is taken by mouth and, when combined with exercise, weight loss and a healthy diet, can work to lower elevated lipid levels.
You can buy Simvastatin tablets when you have a valid prescription from a registered pharmacy like Medicine Direct. We sell Simvastatin in doses of 20mg, 40mg and 80mg. If you order with us before 2pm, we can offer you next day delivery.
What is Simvastatin used to treat?
Simvastatin is part of a class of drugs known as 'statins', which work to lower the production of bad cholesterol. Simvastatin is also able to prevent the production of dangerous fats which are often found in your blood, such as triglycerides, as well as produce good forms of cholesterol.
By lowering your cholesterol levels, you can also lower your risk of heart problems like heart disease or a heart attack, as well as strokes.
Who can take Simvastatin?
Simvastatin is an effective medication for lowering cholesterol levels, but it may not be suitable for everyone to use.
This medicine is suitable for adults and children over the age of 10 years old to take.
You should tell your doctor before taking Simvastatin tablets if:
- You have liver or kidney problems
- You have had an allergic to this or any other medicine in the past
- You have or have had a muscle disorder like fibromyalgia
- You have severe lung disease
- You drink large quantities of alcohol on a regular basis
- You have an underactive thyroid
Simvastatin tablets can also interact with other medication. If you are taking any other medicine for high cholesterol or any other illness, you should make sure your doctor is aware. Please refer to the Warnings and Drug Interactions tab on this page for a list of other medicines you should be cautious of when using Simvastatin.
Possible side effects
Statins for cholesterol are generally considered to be very safe to take. However, like all medications, Simvastatin comes with the risk of certain side effects, although not everyone will suffer from them. You should speak to your doctor if these side effects bother you or do not go away.
A rare but serious side effect of taking this medicine is unexplained muscle pain. You may be more likely to experience this reaction if you are taking a higher dose of Simvastatin, and it may appear weeks or even months into your course of treatment.
You should report any muscle pain or aches to your doctor straight away.
Please note, this list is not exhaustive. For a full list, please refer to the Side Effects tab on this page.
The usual starting dose for adults is between 10mg and 40mg, which should be taken once a day. If you have very high cholesterol levels, your doctor may prescribe you the maximum dose of 80mg.
Based on their age, children will usually be instructed to take one dose of 10mg of Simvastatin in the evening. A doctor may increase this amount after 4 weeks, up to a maximum of 40mg.
At Medicine Direct, we sell the following doses of this medication:
This is the lowest strength of Simvastatin we sell. This is commonly prescribed for children or those with slightly higher than normal cholesterol.
40mg is the maximum strength dose of Simvastatin that is suitable for children. This is the most commonly prescribed form for treating high cholesterol and is to be taken once daily. It is given to patients with diabetes, peripheral vascular disease, a history of stroke, a high risk of a CHD event or other cerebrovascular diseases.
This is the strongest possible dose of Simvastatin, to be prescribed for more serious cases of high cholesterol and related diseases, and is usually prescribed if you have not reached the desired levels of cholesterol on lower strengths of the medicine. Your doctor will have to review your symptoms before prescribing this strength of Simvastatin as it can increase the risk of myopathy.
How to take Simvastatin
It is generally recommended by doctors for patients to take Simvastatin in the evening, once a day, with a glass of water. One of the benefits of the medicine is that it does not effect the stomach, so it is safe to take before or after eating.
Do not open or chew the tablets, they must be swallowed whole. They are also most effective when following other healthy lifestyle choices, such as eating a balanced diet, getting regular exercise, managing your stress and stopping smoking.
Do not drink grapefruit juice while taking Simvastatin.
What if I forget to take it?
If you accidentally miss a dose of Simvastatin, just take your next dose at the scheduled time. You should never take two doses and you should never double up on doses to try and make up for a missed dose.
To ensure you don't forget to take your medication, it helps if you get into a routine of taking it at the same time every day. Some people find it beneficial to set an alarm to remind them to take it.
What happens if I take more than I am supposed to?
Accidentally taking an extra dose of this medicine is unlikely to do you any harm, although you should speak to your doctor if you become worried or if you take more than one extra dose.
How can I buy Simvastatin online in the UK?
Can you purchase Simvastatin over the counter?
What happens if you eat or drink grapefruit while taking Simvastatin?
Can you drink alcohol while taking Simvastatin?
What happens when you stop taking Simvastatin?
Can I crush Simvastatin?
How is high cholesterol diagnosed?
Is it a blood thinner?
What is the best time to take Simvastatin?
What is the drug Simvastatin used to treat?
Are there any other drugs that are similar to Simvastatin?
Simvastatin Serious Side Effects
Certain adverse effects you may experience can be found on the main page. All medicines come with the risk of certain side effects, although not everyone who takes the medicine will get them.
Serious side effects are very rare when using Simvastatin, affecting less than 1 in every 1,000 people who take it.
Nonetheless, you should stop taking the medicine and call a doctor immediately if you experience any of the following serious side effects while using Simvastatin:
- You lose weight, have a cough or feel short of breath – these can be symptoms of lung disease
- Severe stomach pains – this could be a sign of pancreas problems
- Muscle pain, cramps, weakness or tenderness – this could be a sign of kidney damage or muscle breakdown
- You have a skin rash with pink blotches, especially on the palms of your hands or soles of your feet
- You have yellowing skin or the whites of your eyes turn yellow, or you have pale stools or dark urine – these could be symptoms of liver problems
In some cases, you may experience a severe allergic reaction to taking Simvastatin. You should call 999 or go to A&E straight away if you notice any of these symptoms:
- You are finding it difficult to breathe or speak
- You are wheezing
- You have a skin rash that is red, itchy, swollen, blistered or peeling
- You have swelling of the lips, tongue, mouth, face or throat
- You have tightness in the chest or throat
Please note that this list may not be exhaustive; for the full list of possible side effects, you should refer to the patient information leaflet.
Simvastatin Warnings and drug interactions
You should always make sure that your doctor is aware of any medication you are already using. This includes both prescription and non-prescription medicine, herbal remedies, vitamins and supplements.
Certain medicines do not mix well with Simvastatin. You should consult your doctor before taking Simvastatin if you are already taking any of these medications:
- Nefazodone to treat depression
- Certain HIV medications
- Certain antifungals and antibiotics
- Warfarin to treat blood clots
- Certain medicines to treat hepatitis C
- Danazol to treat endometriosis
- Amiodarone to stabilise your heart
- Verapamil, diltiazem or amlodipine to treat heart problems and high blood pressure
- Ciclosporin to treat rheumatoid arthritis and psoriasis
If you need to take any of the above medicines while also using Simvastatin, your doctor may do one of several things:
- Prescribe a different statin medicine for cholesterol such as Atovastatin, Pravastatin, Fluvastatin.
- Prescribe a lower dose of Simvastatin
- Suggest you stop using Simvastatin temporarily
It should be noted that any herbal remedies which contain St. John's Wort (used to treat depression) will reduce the amount of Simvastatin in your blood, hindering the medication's effectiveness.
If you are currently using any medicines that contain St. John's Wort, or are thinking of doing so, you should make sure your doctor knows, as this can stop Simvastatin from working properly.
Pregnancy and breastfeeding
Simvastatin is not recommended for women who are pregnant. If you are currently pregnant, are trying to get pregnant, or think you may be pregnant, you should make sure you tell your doctor. If you become pregnant while taking Simvastatin, you should stop taking the medicine and tell your doctor as soon as possible.
Similarly, this medication may not be suitable for women who are breastfeeding. There is not enough research out there to prove either way as to whether this medicine is harmful to babies, but small amounts of this medicine can make its way into your breast milk. You should speak to your doctor if you are breastfeeding, before you start to use this medication.
The active ingredient contained in this medication is Simvastatin, 10mg, 20mg or 40mg, depending on the dose you have been prescribed for your cholesterol.
Other ingredients also contained in the medicine are: Butylated hydroxyanisole (E320), ascorbic acid (E300), citric acid monohydrate (E330), microcrystalline cellulose (E460a), pregelatinized maize starch, lactose monohydrate, magnesium stearate (E470B)
How it works - get your medicine in 3 simple steps
- 1 Choose your treatment Select the treatment or medication you need and answer a few questions online regarding your condition.
- 2 Online consultation Our Independent Prescribers will review your questions and assess your suitability for the medication.
- 3 Receive your delivery Your medication is dispensed and delivered directly to you from our UK based Pharmacy.