Treclin Gel

  • Applied as a topical gel
  • Used to treat mild - moderate acne
  • Contains the retinoid Tretinoin
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Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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Treclin Gel for the treatment of Acne

There is no quick fix when it comes to treating acne, it can have a huge impact on self-confidence, quality of life and has also been linked to depression. Fortunately, Acne can be treated with Treclin Gel, which contains a combination of the powerful Retinoin (Tretinoin) and the antibiotic (Clindamycin). 

What is Treclin gel?

Treclin gel is used as an acne treatment for adults and children who are over the age of 12.

It is a topical medicine which contains two active substances: tretinoin and the antibiotic clindamycin. These ingredients are combined to provide a comprehensive treatment for acne.

You can only buy Treclin gel when it has been prescribed by a doctor for you.

What is Treclin gel used to treat?

A topical gel, Treclin can be used to treat moderate cases of acne by preventing the growth of bacteria.

It is applied once daily before going to bed and will normally start to improve your acne after a few weeks. However, it can take up to 12 weeks for some people to notice the full benefits of this medicine. It is important you are consistent with your applications of the gel.

What causes acne?

Acne is a very common skin condition, particularly in teenagers and young adults, although it can occur at any age. About 95% of people aged 11 to 30 have acne to some degree.

It can be caused by a number of reasons, but it is most commonly a result of a change in hormone levels. This change causes the glands next to the hair follicles to produce a higher amount of sebum (oil) than usual, which changes the activity of bacterium that would normally be harmless to cause inflammation. This creates spots.

How does Treclin work?

Treclin contains two active ingredients: clindamycin and tretinoin. Clindamycin is an antibiotic that works to kill the bacteria that live on the skin and cause acne.

At the same time, tretinoin is able to reduce the skin cells' ability to stick together. This makes it easier for you to shed dead skin cells, which stops them from blocking your pores and follicles.

How to use Treclin gel

The recommended dose of Treclin is a pea-sized amount of gel, which should be applied once a day at bedtime.

  1. Wash your face using a mild soap and warm water, then pat your skin dry with a towel.
  2. Squeeze a pea-sized amount of gel onto your fingertip.
  3. Dab the gel onto your forehead, nose, chin and both cheeks, then spread it over your whole face. Make sure the face is evenly covered with it.

It will normally take several weeks before Treclin reaches its optimum effect. This may take up to 12 weeks for some people. Talk to your doctor if you have used Treclin for 12 weeks and your acne has not gone away, or if it has become worse.

Always follow your doctor’s instructions when using a prescription medicine. Full instructions can be found in the patient information leaflet, which will come with the gel. 

Does Treclin Gel help to reduce the appearance of wrinkles?

Retinoids have long been studied when it comes to slowing down the appearance of wrinkles and the natural ageing process. Tretinoin, the active ingredient within Treclin Gel, is the retinoid that has been studied the most.

A clinical study identified Retinoins in particular Tretinoin as the most promising ingredients available for the treatment of wrinkles and other effects of ageing on the skin.

Possible side effects

Like all medicines, Treclin gel comes with the risk of certain side effects, although not everyone who uses it will suffer from them.

The following reactions may affect up to 1 in every 100 people:

  • Acne, dry skin, redness of the skin, increased sebum production, photosensitivity reaction, itching, rash, scaly rash, scaling of the skin, sunburn
  • Burning, inflamed skin, dryness, redness of the skin on the area(s) you have applied Treclin gel

If any of these symptoms persist or concern you, you should speak to your doctor.

This list is not exhaustive. Please, refer to the Side Effects tab on this page for a full list of adverse reactions you may experience while using Treclin gel.

Who can use Treclin gel?

Treclin gel is an effective acne treatment, but it may not be suitable for you to use.

Do not use Treclin without speaking to your doctor if you suffer from any of the following:

  • You are allergic to lincomycin
  • You are allergic to any of the ingredients contained in Treclin
  • You are suffering from acute eczema
  • You have a history of colitis when using other antibiotics
  • You have a chronic inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
  • You or a member of your family has ever had skin cancer
  • You are suffering from rosacea
  • You are suffering from other acute inflammatory conditions of the skin
  • You have any special type of acne vulgaris

Always read the patient information leaflet thoroughly for a comprehensive list of reasons why Treclin might not be a suitable treatment for you to use.

Further information can be found under the Warnings tab on this page.

Can you buy Treclin gel over the counter?

No, you cannot buy Treclin gel unless it has been prescribed for you by a doctor.

Can you buy Treclin gel online in the UK?

Treclin gel is only available on prescription, but you can buy it online from regulated pharmacies like Medicine Direct by completing an online consultation. This involves filling out a questionnaire for a certified doctor, pharmacist or prescriber to review, who will assess your condition to make sure Treclin is an appropriate treatment.

Next day delivery is available on orders placed by 2pm.

Medicine Direct is a fully regulated UK pharmacy, meaning we can guarantee nothing but safe and approved medicine. Never buy any medicine online from anywhere other than regulated pharmacies. You can see who we are regulated by on our About Us page.

Treclin alternatives

If Treclin gel is not suitable for you, do not worry, a large number of acne treatments are available.

Other retinoin options include Differin Gel, it is also available as a cream. It contains the topical retinoid Adapalene.

Topical gels like Duac and Acnecide can also be ordered from Medicine Direct after an online consultation with a registered prescriber.

We also stock prescription oral medicines like Erythromycin.

Treclin Gel Dosage and Directions

Out pharmacists and prescribers follow NICE guidelines when prescribing Treclin Gel

Always use Treclin gel exactly as instructed by your doctor. Read the patient information leaflet thoroughly before you apply Treclin gel; speak to your doctor if you are unsure of how to apply it.

What if I use too much?

Using more Treclin gel than you are supposed to will not treat your acne any more effectively.

You may suffer redness or peeling if you apply too much Treclin. If this happens, wash your face with gentle soap and warm water; speak to your doctor if your symptoms do not improve.

What if I forget to use it?

Never double dose medicine to make up for missing a previous dose. If you forget to apply the gel, just apply it the next evening.

To effectively stop the growth of bacteria and treat acne, it is very important that you are consistent with your treatment. Some people find it useful to set an alarm at bedtime, to remind them to apply Treclin.

How long will I need to use it for?

Most people will notice a sizeable improvement in their acne after they have been using Treclin for between 4 and 12 weeks. Do not stop using the treatment before your doctor tells you to, this could affect the results and hinder the medicine's effectiveness.

Treclin Gel FAQ's

How long does Treclin take to work for acne?


Treclin gel normally takes between 4 and 12 weeks before you see a significant improvement in your skin. To ensure you get the most from this medicine, it is important that you use it every day.

Does Treclin gel make your skin sensitive to sunlight?


Treclin gel contains tretinoin, which can make your skin more sensitive to light. This can cause sunburn, so you are advised to use sunscreen when you go outside and avoid sunlamps while using Treclin.

How long can you use Treclin gel for?


Treclin should not be used for longer than 12 consecutive weeks unless your doctor says so. You should have your acne reviewed after this time to see how the treatment is progressing.

Does Treclin make your skin peel?


Using too much of this gel may result in side effects such as redness, discomfort or skin peeling. Never apply more than the recommended dose – this will not provide faster treatment.

Is Treclin a retinoid?


Treclin gel contains two active ingredients, one of which is a retinoid (tretinoin), the other is an antibiotic.

Does tretinoin fade acne scars?


It has been reported that tretinoin encourages cell turnover, which can even skin tone and also reduce the appearance of acne scars. However, these effects may vary from person to person.

Can I use Treclin gel if I’m pregnant?


You should not use Treclin gel if you are pregnant or trying to get pregnant. Women of childbearing potential should not use this medication unless they are using contraception.

What if Treclin does not help my acne?


Your doctor will want to review your treatment, normally after 12 weeks. If your acne has not improved or has got worse, they may decide to prescribe you a different medication.

What should I do if I experience side effects?


If you suffer redness or irritation, stop using Treclin until these symptoms have gone. When you start using it again, only apply it every other day for the first week. If you have an allergic reaction to Treclin, seek medical attention straight away.

When should I apply Treclin?


It is best to apply treclin gel once daily, before bedtime.

Will my acne return if I stop using Treclin?


Yes, it is possible that your acne could return if you stop using treclin gel. You should always finish your course of treatment unless advised to stop by your doctor. Completing your course of treatment will increase the chances of your acne not returning after treatment.

Will treclin gel make my acne worse?


It is possible that Treclin Gel may make your acne worse within the first few weeks of treatment. It will take some time for your skin to get used to the treatment and for the treatment itself to start working and improving your acne.

What is Tretinoin purge?


During the first several weeks of using Treclin Gel, your skin is likely to experience a breakout of spots. This is called the "Tretinoin purge". The tretinoin purge is likely to last for around four to six weeks, however not everyone that uses Treclin Gel will experience this.

Can I use Treclin Gel with other acne treatments?


No, its important when using Treclin Gel that you are not using any other treatment for your acne. Using two different acne treatments at once could damage your skin, increase your chances of adverse side effects and also make your acne worse. 

Treclin Gel Serious Side Effects

The more common side effects associated with this medication can be found on the main product page. In some cases, you could experience rare adverse reactions while you use Treclin gel.

Rare side effects of Treclin gel may include:

  • Feeling hot, pain
  • A headache
  • Herpes simplex (cold sores)
  • Skin bleeding, inflammation, burning sensation, loss of skin pigmentation, or skin irritation
  • Irritation, discolouration, damage, swelling or superficial skin damage to the area of application
  • Eye irritation
  • Hypersensitivity
  • Gastroenteritis
  • Underactive thyroid gland

In rare cases, you may experience a serious allergic reaction to Treclin and require immediate treatment in hospital.

Stop using Treclin and either call 999 or go to A&E straight away if you suffer from any of these symptoms:

  • You are wheezing
  • You get a skin rash that is red, swollen, itchy, blistered, or peeling skin
  • You have swelling in your face, mouth, lips, throat, or tongue
  • You are finding it difficult to breathe or speak
  • You have tightness in your throat or chest

Always read the medicine's patient information leaflet before you start to apply Treclin. The above lists may not be exhaustive.

Treclin Gel Warnings and drug interactions

Treclin gel may interact with other medicines.

Always make sure that your doctor is aware if you are currently taking any other medicines. This includes both prescription and non-prescription medications, herbal remedies, vitamins and supplements.

In particular, make sure they are aware if you are currently taking any of the following medicines:

  • Any medicines that contain sulphur, salicylic acid, benzoyl peroxide or resorcinol or any chemical abrasives
  • While using Treclin, you should not use any medicated soaps cleansers or scrubbing solutions with strong drying effects

For more information on medicines that interact with Treclin Gel.

Other warnings

Speak to your doctor if you get acute inflammation of the skin while using this medicine.

Consult your doctor if you have atopic eczema before using this gel.

Pregnancy and breastfeeding

Treclin gel is not recommended for use by women who are pregnant. Inform your doctor if you are currently pregnant, think you may be pregnant, or are trying to get pregnant.

You should also tell your doctor if you are currently breastfeeding.

Treclin Gel Ingredients

The main active ingredients within this medicine are: Tretinoin and Clindamycin phosphate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Published on: 12/10/2020

Updated on: 20/08/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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