• Treatment for Migraine attacks
  • Relieves pain caused by Migraines
  • Fast acting

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What is Zolmitriptan?

Zolmitriptan is commonly sold under the brand name Zomig, among others. It is a selective serotonin receptor agonist and is used in the treatment of migraines, with or without aura and cluster headaches. Zolmitriptan is a member of the triptan class of drugs.

Zolmitriptan is prescribed to treat migraines, helping to relieve the unpleasant symptoms of this common issue such as headaches, nausea and sensitivity to light and sound. Ideally, it should be taken at the onset of a migraine attack, although it can also be taken later on into an attack.

Zolmitriptan should not be used to prevent migraines, only to relieve them when they occur.

This medicine is only available on prescription and can be taken by adults over 18 years of age.

What is Zolmitriptan used to treat?

Zolmitriptan tablets are sold as an acute treatment for migraine attacks. They are available to buy online from Medicine Direct in packets of either 6, 12 or 18 tablets.

Migraines are believed to be caused by the widening of blood vessels in your head. A migraine treatment like Zolmitriptan is thought to reduce the widening of the blood vessels, thus helping to relieve the pressure and alleviate the symptoms associated with migraines, including nausea, dizziness and headaches.

You will likely be prescribed Zolmitriptan when over the counter painkillers like paracetamol have not worked to ease your migraines.

Whilst the exact cause of a migraine is not know, Zolmitriptan continues to be widely prescribed and is effective at relieving the symptoms of a migraine.

How does Zolmitriptan work?

Triptans like Zolmitriptan work to relieve the symptoms of migraines by helping to narrow the blood vessels around the brain, which are believed to expand at the onset of a migraine attack.

By narrowing the blood vessels back to their normal size the pressure is relieved, as is the throbbing headache that comes with a migraine. Furthermore, this helps to ease the other symptoms that are caused by migraines, like nausea.

Zolmitriptan is a fast acting medicine and should have effectively relieved your symptoms after around one hour.

How to take Zolmitriptan

Take Zolmitriptan as your doctor or pharmacist has instructed you. Always read the patient information leaflet for comprehensive instructions.

For the fastest results, take Zolmitriptan as soon as you feel a migraine headache starting. Zolmitriptan can also be taken later on during a migraine attack.

Take one 2.5mg tablet. Swallow the tablet whole with a glass of water.

If you are still suffering from symptoms, or if the first dose is ineffective, a second tablet can be taken after at least two hours.

Do not take more than two doses in 24 hours unless your doctor prescribes this.

Who can take Zolmitriptan?

Zolmitriptan is an effective medication to treat migraine symptoms, but it may not be suitable for everyone to use.

You should not take Zolmitriptan if:

  • You are allergic to zolmitriptan or any ingredients in the medication
  • You have high blood pressure
  • You have or have ever had heart problems, including a heart attack and angina, or have ever had any symptoms of a heart problem, like tightness in the chest or shortness of breath
  • You have liver problems
  • You are at risk of heart disease
  • You have headaches that differ to the usual ones brought on by migraines
  • You have Wolff-Parkinson-White syndrome
  • You are taking any medicine to treat depression
  • You have had a stroke or exhibited symptoms similar to those of a stroke
  • You are taking any other medicines to treat a migraine (see the Warnings tab for the full list of medicines that interact with Zolmitriptan)

If you have any questions or concerns, you should speak to your doctor or pharmacist before you start to take the medication. This list is not exhaustive; always read the patient information leaflet.

Can you buy Zolmitriptan over the counter?

Zolmitriptan cannot be bought over the counter. You will need a prescription from your doctor to purchase this medication.

Can you buy Zolmitriptan online in the UK?

Medicine Direct stocks Zolmitriptan, but it is a prescription-only medicine (POM). To buy Zolmitriptan online from our pharmacy, you will need to first fill out our online consultation form for one of our prescribers to assess. This is to make sure that it is a suitable medicine for you to take. You will also need to have been diagnosed with migraines by your doctor.

We can offer you next day delivery if your order is placed by 2pm.

Medicine Direct is fully regulated by the General Pharmaceutical Council, which means that all of our medicine is safe and approved for sale in the UK. For your own safety, never buy medication online unless it is from a registered pharmacy.

Zolmitriptan alternatives

You can buy various other triptan medicines online from Medicine Direct. These medicines work in the same way as Zolmitriptan. We also stock migraine medicines such as Sumatriptan and Almotriptan. Just complete an online consultation form and one of our registered doctors or pharmacists will review your answers to ensure your desired medication is safe for you to take.

Zolmitriptan is also available as a branded version, Zomig 2.5mg/5mg tablets.

Imigran nasal sprays are available to treat migraines, as are Imigran tablets. These medicines contain sumatriptan as the active ingredient.

We also sell non-prescription alternatives to Zolmitriptan. Anadin Extra caplets provide effective relief from migraines, as well as the likes of toothache and period pain. Containing paracetamol and aspirin, Anadin Extra is a comprehensive treatment for migraine symptoms. They also contain caffeine, which helps the medicine to get to work as quickly as possible, providing rapid relief from pain.

Browse our full range of migraine treatments on the Migraine condition page.

Zolmitriptan Dosage

Our pharmacists and prescribers follow NICE guidelines when prescribing Zolmitriptan.

Always make sure you take this medication exactly as instructed by your doctor or pharmacist.

Zolmitriptan tablets should be swallowed whole with a drink of water. The tablets can be taken with or without food.

You can take Zolmitriptan tablets as soon as you start to suffer a migraine attack.

You can take a second dose after two hours if your migraine symptoms have not got any better or come back. Do not take more than two doses in a single 24 hour period. The maximum daily dose of Zolmitriptan is 10mg (2 5mg tablets).

If this medication does not provide effective relief from your condition, go back to your doctor, who may prescribe a different course of treatment for you to try.

Zolmitriptan Side Effects

The common side effects of taking Zolmitriptan can be found on the main product page.

In rare cases, you may experience more serious adverse reactions. If you notice any of the below symptoms, you should stop taking Zolmitriptan and seek medical attention straight away:

  • Spasms of the blood vessels in the gut – symptoms include stomach pain or diarrhoea
  • Bleeding in the brain or a stroke
  • Angina (pain in the chest or shortness of breath)
  • Very fast heartbeat
  • Urinating more often or not urinating at all
  • Higher blood pressure

In some cases, you may experience a severe allergic reaction to these tablets and require immediate treatment in hospital.

You should call 999 or go to A&E immediately if you experience any of the below symptoms:

  • Swelling of the throat, lips, mouth, face or tongue
  • You are wheezing
  • You have a skin rash that is itchy, red, swollen, blistering or peeling
  • Tightness in the chest or throat
  • You are finding it difficult to breathe or speak

Always read the patient information leaflet for the full list of side effects. If you have any concerns, you should speak to your doctor or pharmacist before you take Zolmitriptan.

Zolmitriptan Warnings and drug interactions

Zolmitriptan may interact with other medicines.

Before you take Zolmitriptan, you should inform your doctor and pharmacist of any other medicine you are currently using. This includes both prescription and non-prescription medicines, herbal remedies, vitamins and supplements.

You should make sure your doctor and pharmacist is aware if you are taking any of the following:

  • Any medicines to treat depression
  • Serotonin norepinephrine reuptake inhibitors (SNRIs)
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Cimetidine
  • Any quinolone antibiotics

If you take any other triptans to treat a migraine or any other conditions, leave at least 24 hours before you take Zolmitriptan. Similarly, after taking Zolmitriptan, leave at least 24 hours before you take any other triptans.

After you take Zolmitriptan, wait at least 6 hours before you take any ergotamine or ergot-type medicines.

You should not drive or operate machinery if you feel dizzy or sleepy as a result of taking this medicine.

If you have any questions or concerns at all, do not hesitate to speak to your doctor or pharmacist.

Pregnancy and breastfeeding

There is not sufficient research to say that this medication is completely safe for women who are pregnant or breastfeeding. There is no evidence to suggest that Triptans used during pregnancy increase the risk of miscarriages or increase the risks of congenital malformations.  

If you are currently pregnant, think you might be pregnant or are trying to get pregnant, you should inform your doctor before you start to take Zolmitriptan.

Similarly, if you are currently breastfeeding you should let your doctor know, as small amounts of the medicine can get into your breast milk and be passed onto the baby.

Zolmitriptan Ingredients

The main active ingredient within this medicine is: Zolmitriptan

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Published on: 12/10/2021

Updated on: 28/07/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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