Domperidone 10mg Tablets

  • Anti-sickness medicine
  • Used to treat Nausea
  • Prevents nausea and vomiting

Maximum quantity per treatment: 30 tablets

Please note brand received may vary

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Buy Domperidone 10mg anti-sickness tablets

Domperidone is an anti-sickness medicine that is used to alleviate the symptoms of nausea. Domperidone is also commonly known by its brand name Motilium, which also contains 10mg of domperidone as it's active ingredient.

Nausea can be triggered by a multitude of reasons, for many people; feeling sick will come and go on its own without the need for treatment to help with symptoms.

For individuals that suffer from nausea regularly, domperidone is effective at relieving the symptoms of nausea including vomiting.

You can buy domperidone 10mg tablets online from Medicine Direct after completing a consultation with one of our UK based prescribers.

Domperidone summary:

Type Antiemetic
Prescribed for Nausea and Vomiting
Side effects Dry mouth
Available as Tablets
Dose 10mg
Price £14.99


What are Domperidone 10mg tablets?

Domperidone 10mg tablets belong to a group of medicines known as antiemetic drugs. They are taken to stop you from feeling sick or needing to vomit.

Domperidone can be taken by adults and children over the age of 12 years.

This medicine comes as tablets or a liquid you swallow. You can only buy Domperidone when you have a prescription.

What are Domperidone 10mg tablets used to treat?

Domperidone is used as a treatment for nausea and vomiting. It can also be used to alleviate stomach pain if you are having end of life care (palliative care).

Domperidone is sometimes prescribed to increase milk supply in women who are finding it difficult to breastfeed. However, it will only be prescribed for this problem if other treatments have failed to work effectively.

How does Domperidone work?

Domperidone works by blocking the messages that are passed between the brain and the digestive system. This causes the muscles at the exit of your stomach to relax, reducing the likelihood of you needing to vomit.

Domperidone is also able to block messages sent between parts of your brain known as the chemoreceptor trigger zone (CTZ) and the vomiting centre. This helps to relieve nausea and stop you from vomiting.

This medicine gets to work after around 30 to 60 minutes.

Domperidone dose

The usual dose for adults and children over 12 is one tablet up to three times a day.

Do not take more than three tablets a day.

Your dose may be lowered by your doctor if you have any kidney problems.

How to take Domperidone

Swallow Domperidone tablets whole with a glass of water. Do not crush or chew the tablets.

Take the tablets between 15 and 30 minutes before you eat a meal.

How long you need to use Domperidone will be decided on by your doctor. Most people find that their symptoms are cured within 3-4 days. Do not take this medicine for longer than 7 days without speaking to your doctor.

Refer to the patient information leaflet for full instructions.

Who can take Domperidone tablets?

Domperidone is an effective treatment for nausea and vomiting, but it may not be suitable for everyone to use.

Domperidone tablets are not available in different doses, which means if Domperidone 10mg tablets are not best suited to treat your condition, your doctor or prescriber may choose to prescribe an alternative treatment altogether, instead of reducing your dose.

This medication is only recommended for adults and adolescents aged 12 years old and above. In some cases it is prescribed for babies and young children, but only by a specialist doctor.

You should inform your doctor if any of the following conditions apply to you before you start to use this medicine:

  • You weigh less than 35kg
  • You have ever had bleeding from your stomach or gut
  • You have ever had an allergic reaction to domperidone or any other medicine in the past
  • You have any conditions caused by a bowel obstruction, such as Crohn's disease or diverticulitis
  • You have a tumour in your pituitary gland
  • You have an irregular heartbeat
  • You have liver, kidney or heart problems
  • You are pregnant or breastfeeding
  • You have recently had abdominal surgery

You are not normally advised to take this medicine while pregnant or breastfeeding.

This list is not exhaustive. Always read the patient information leaflet for full warnings.

Can you buy Domperidone 10mg tablets over the counter in the UK?

No, you cannot buy Domperidone 10mg tablets over the counter; it is a prescription only medicine. You can only buy Domperidone if you have been prescribed it by a UK doctor or prescriber.

Up until 2014 you could buy Domperidone over the counter, but it was reclassified as prescription-only that year.

Can you buy Domperidone 10mg online in the UK?

Yes, you can buy Domperidone 10mg tablets online in the UK from most online pharmacies. You will need to complete an online consultation so a doctor or prescriber can assess your medical condition to ensure you are receiving the most suitable treatment for your condition.

When you buy this medication from Medicine Direct, next day delivery is available if you order by 2pm. For your own safety, you should only order medicine online from regulated pharmacies, like Medicine Direct.

Domperidone alternatives

There are several different anti-sickness medicines available from Medicine Direct, which work in similar ways to relieve nausea and vomiting. There isn’t enough evidence to prove that one particular medicine is the most effective at relieving these symptoms, so you might need to try more than one to find the best treatment for you.

Prochlorperazine 5mg tablets are a widely prescribed medicine to ease the symptoms of nausea. This medicine works to block the dopamine receptors in the nausea-causing part of the brain. Prochlorperazine comes as tablets and also as buccal tablets, which dissolve in the mouth and are ideal for people who have trouble swallowing medicine. They are also available in the branded version, Stemetil 5mg tablets.

Cyclizine works in a similar way to Domperidone and also provides relief after 30 to 60 minutes.

Domperidone Dosage

Always use Domperidone exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly before you start your course of treatment. Speak to your doctor or pharmacist if you are not sure of how to take it.

All of our Doctors and Pharmacists follow NICE guidelines when prescribing Domperidone.

Domperidone is for oral consumption only. Each tablet should be swallowed whole with a glass of water. Do not crush or chew the tablets.

Adults and children over 12 years old

The usual dose is one tablet, to be taken 3 times a day, ideally before a meal.

Do not take more than 3 tablets a day.

If you have any kidney problems, your doctor may instruct you to take a lower dose or to take Domperidone less often.

How long will I need to take it?

Your nausea and vomiting symptoms will normally be resolved within 3-4 days of taking this medicine.

You should not take Domperidone tablets for longer than 7 days, unless you have been advised to do so by your doctor.

What if I forget to take it?

If you accidentally miss a dose of Domperidone, take the medication as soon as you remember, as long as it is not almost time for your next scheduled dose.

If it is almost time for your next dose, skip the missed dose and continue taking Domperidone as usual.

Do not double dose to try and make up for a missed dose.

What if I take more than I am supposed to?

Taking too much Domperidone can be dangerous to your health.

Taking more than the prescribed dose can result in a fast or irregular heartbeat.

If you or someone else has taken too much Domperidone, you should call 111 or speak to your doctor for advice straight away.

How long will Domperidone take to work?

You should start to notice Domperidone working after around 30 to 60 minutes.

Why is Domperidone not usually recommended for children under 12?

Research has shown that young children and babies suffering from nausea or vomiting due to a stomach bug are not helped by Domperidone. Furthermore, a link has been identified between taking Domperidone and heart problems in a small number of people.

How does it compare to similar medicines?

Domperidone is an anti-emetic medicine. These types of medicine work in very similar ways, but Domperidone is less likely to cause tiredness. You can also try different types of medication to help with nausea, such as cyclizine and prochlorperazine.

Is Domperidone good for acid reflux?

Domperidone can be used to treat regurgitation as it works to decrease postprandial reflux time. This should be prescribed by a doctor.

Can I take Domperidone and Omeprazole together?

Domperidone and Omeprazole are sometimes prescribed together to treat acidity and heartburn. These medicines can be taken together, but you should only do so on your doctor’s recommendation.

Can I drink alcohol with it?

Alcohol may exacerbate certain side effects, such as sleepiness. For this reason, you are advised to not drink alcohol while taking Domperidone.

Is Domperidone a laxative?

No, this medicine will not work to relieve constipation and should not be taken to treat this problem. However, Domperidone can cause diarrhoea as an uncommon side effect.

How long will I take it for?

You should take this medicine for the shortest time possible, at the lowest effective dose. You should not take Domperidone for longer than one week without talking to your doctor.

Will it affect my contraception?

No, Domperidone has no direct effect on any form of contraception, including the morning after pill. Nonetheless, if you do vomit, any contraceptive pills you are taking may not provide complete protection from pregnancy. If this happens, refer to the information that came with your contraception for guidance on what to do.

When should I take Domperidone?

Take Domperidone 15 to 30 minutes before you eat a meal and, if required, before you go to bed.

Domperidone Side Effects

Common side effects

Like all medicines, Domperidone comes with the risk of certain side effects, although not everyone who takes the medicine will have them.

The most common side effect of using this medication is dry mouth.

Below is a list of less common side effects you may suffer while using Domperidone. You should speak to your doctor if any of these reactions bother you or do not go away:

  • Feelings of nervousness, anxiety or agitation
  • A decreased sex drive or loss of interest in sex altogether
  • Diarrhoea
  • Rash
  • Headaches
  • Hives
  • Painful or tender breasts
  • Feeling dizzy
  • Sleepiness
  • Milk discharge from your breasts
  • Feeling weak
  • Itchiness

We recommend you read the patient information leaflet before using this medicine. You can find the patient information leaflet located inside your box of medicine also.

Below is a list of side effects which can occur when you use this medication. It is not known how frequently these reactions may occur.

Speak to your doctor if you find you suffer from any of the following:

  • Enlarged breasts in men
  • Upward movement of the eyes
  • You are unable to urinate
  • There are changes in certain laboratory test results
  • A stop in menstrual periods in women
  • Restless legs syndrome
  • Depression

Serious allergic reaction

In some cases, patients may find that they suffer from a serious allergic reaction after they have used this medicine.

You should call 999 or go to A&E straight away if you have any of the following symptoms:

  • You are wheezing
  • You have swelling in your mouth, lips, tongue, face or throat
  • You are finding it hard to speak or breathe
  • You have tightness in your chest or throat
  • You have a skin rash that is red, blistered, swollen, itching or peeling skin

You might require immediate treatment in hospital.

Domperidone Warnings and drug interactions

Domperidone can interact with certain drugs when used at the same time, which can hinder its effectiveness and also increase your risk of side effects.

You should also inform your doctor if you are currently using, or have recently used, any other medicines. This includes both prescription and non-prescription medication, herbal remedies, vitamins and supplements.

In particular your doctor should be made aware if you are currently taking:

  • Medicines for cancer, or if you are having treatment for cancer
  • Any medicines used to treat the HIV infection
  • Medicines to treat malaria
  • Antidepressants or antipsychotic medicines
  • Medicines to treat any heart conditions or high blood pressure
  • Any antibiotics or medicines for fungal infections

You should only use one anti-sickness treatment at any one time. If Domperidone does not work for you after a few days, you should speak to your doctor, who will recommend other treatments available for you.

Never order medication online unless it is from a UK pharmacy that is registered with the General Pharmaceutical Council, like Medicine Direct.

All of our doctors are registered with the General Medical Council (GMC), and if you order with us before 2pm, next day delivery is available.

Order with us today, to begin your treatment immediately.

Mayo Clinic explains the things you need to consider before taking Domperidone, including a list of medicines that interact with Domperidone.

Pregnancy and breastfeeding

Domperidone is not normally recommended for women who are currently pregnant.

If you are pregnant, think you might be pregnant, or are trying to get pregnant, you should speak to your doctor before you use this medicine.

If you are seeking this medicine to treat morning sickness, Cyclizine Hydrochloride tablets are typically a better alternative to treat morning sickness during pregnancy.

Domperidone is not recommended for women who are currently breastfeeding, because it passes into the breast milk in small quantities. You should speak to your doctor for more information, as alternative medicines may be more suitable for you.

Domperidone is sometimes prescribed to increase a woman's milk supply, but research has shown that this can give your baby an irregular heartbeat. Speak to your doctor about the possible benefits and health risks associated with taking this medication while breastfeeding.

Domperidone Ingredients

The main active ingredient within this medicine is: Domperidone maleate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Published on: 12/10/2020

Updated on: 11/06/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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