Naproxen is typically prescribed to provide effective treatment in a number of conditions such as Arthritis, Muscle/joint pain, back pain, Period pains and Gout. It is an anti-inflammatory medicine and is effective in providing pain relief by reducing the pain inflicting hormones in our bodies.


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What is Naproxen?

Naproxen is a non-steroidal and anti-inflammatory drug (NSAID) composed of ingredients which tend to cure minor diseases or pains such as fever, inflammation, stiffness and swelling. It is a Sodium salt sold under the name of Naproxen to treat joint pains such as arthritis, stiffness and swellings caused due to joint aches and fever.

The medicine when it gets into the body of a human being fights against the flaming agents present in the body conclusively soothing inflammatory reactions caused by them. Naproxen is the drug which belongs to the group of anti-inflammatory medicines used to cure similar kinds of pains with certain specifications, so if not worked well on any individual then it can be replaced with any other drug of similar family. However, the medicine is available in various potencies such as 250 mg and 500 mg but should be taken as prescribed by the doctor to avoid hazardous consequences.

Naproxen and Paracetamol

It is fine to take Naproxen with paracetamol as these two medicines do not counteract each other. You can also take other opioid type painkillers such as Co-codamol with Naproxen. Paracetamol can provide other effective pain relief for certain conditions. This works by stopping the messages our body sends to our brain when it feels pain. It is always essential top check the ingredients listing when purchasing medication over the counter to ensure that there are no ingredients that can interact with Naproxen or any of its ingredients. 

Ibuprofen must not be taken with Naproxen as this can result in many side effects.

Naproxen Dose

Naproxen is a highly effective anti inflammatory medication and can be used to treat a multiple of conditions that vary in severity and pain.

Naproxen 500mg

This is the strongest dosage of Naproxen and is mainly used in adults typically to treat conditions such as Arthritis, Osteoarthritis and painful Period Pains. The dosage of the medication that is recommended by our doctor is dependent on the severity of your condition and the pain that you are feeling.

Naproxen 250mg

Naproxen 250mg tablets can be used to treat the same conditions as Naproxen 500mg tablets, however this strength of Naproxen will typically be prescribed when the pain is not as severe. Naproxen 250mg tablets are prescribed in the uk to treat Period pains, arthritis and Osteoarthritis as well as muscle inflammation and pain.

What is Naproxen used for?

Naproxen can be used for a wide range of conditions due to its anti-inflammatory properties. It can provide effective pain relief for conditions and symptoms that can be rather painful for the individual that is experiencing them.

Most commonly, Naproxen is used for the below conditions:

Back Pain and General Pain

Naproxen has proven to be an affective medication for a number of chronic pain conditions. Due to its anti-inflammatory properties, Naproxen is widely prescribed for conditions such as chronic back pain and Sciatica. Although Naproxen will not cure these conditions, the pain relief that it can provide on a short term basis can allow individual’s suffering to go about their normal day to day activities.

250 mg to 500 mg (naproxen) or 275 mg to 550 mg (naproxen sodium) orally twice a day.


Osteoarthritis is a type of Arthritis, in fact; it is the most common type of arthritis in the UK and causes joints to become painful and stiff. With most forms of Arthritis, this condition can affect any joint in the body, however it most commonly targets the hands, knees and hips. The chances of developing Osteoarthritis typically increases with Age, the condition is also known to affect more women than men.

The standard Naproxen dosage for Osteoarthritis is:

250 mg to 500 mg (naproxen) or 275 mg to 550 mg (naproxen sodium) orally twice a day.


Naproxen is most commonly prescribed for arthritis, the recommended dosage for naproxen when treating this condition is 250mg or 500mg capsules consumed twice per day.


Naproxen is widely prescribed to treat the painful symptoms of Gout. Gout can cause sudden bouts of pain and is caused by excess Uric Acid in the body. The uric acid then crystalizes around a variety of joints, most commonly the base of the big toe. Gout attacks can come on extremely sudden and most commonly occur in the middle of the night.

Initial dose: 750 mg (naproxen) or 825 mg (naproxen sodium) orally once on first day of attack.
Following initial dose: 250 mg (naproxen) or 275 mg (naproxen sodium) orally every 8 hours until attack subsides.

Menstrual/Period Pains

Period Pains are a common and natural occurrence of the female body whilst going through the menstrual cycle. Although sometime painful, it is a completely normal in women that regularly have their periods. Period pains usually feel like muscle cramps around the stomach area, although this can also be felt in your thighs and lower back.

The typical dosage of Naproxen for Painful Periods is:

550 mg orally once, followed by 275 mg orally every 6 to 8 hours or 550 mg orally every 12 hours as needed.

Naproxen Risk Factors and Warnings

Naproxen can help with a wide variety of conditions; however it is not always suitable for everyone especially if the individual is suffering from any other below conditions

  • Have had any allergic reaction to any other medications or other NSAID's including ibuprofen
  • Have suffered from Stomach ulcers
  • Have high blood pressure
  • Any autoimmune disorders such as lupus
  • Heart failure
  • Crohns disease or ulcerative colitis
  • Blood clotting disorders

 Please tell your GP or Pharmacist if you are/have suffering from any other above conditions.

Naproxen Side Effects

Incorrect usage of the tablet can lead to hazardous consequences such as:

  • High blood pressure
  • Cough
  • fever
  • skin rash
  • sneezing
  • sore throat
  • swelling of the face, fingers, feet, or lower legs
  • nausea;
  • vomiting;
  • Ringing in your ears
  • Mild itching

Naproxen Pregnancy Warning

Naproxen is not recommended during pregnancy particularly in women who are 30 weeks or more. However Doctors are still able to prescribe Naproxen during pregnancy is the benefits far outweigh the risks.

Naproxen has been linked to a number of birth defects, when consumed during pregnancy, such as damage to the baby’s blood vessels and heart. It is also believed that there is a link between women taking naproxen in the early stages of pregnancy and miscarriage.

Naproxen can still be prescribed to pregnant women, however we recommend talking to your GP about the potential risks. Your doctor will assess how far into your pregnancy you are as well as the condition that you will be taking naproxen for. Your Doctor may be able to recommend other treatments that present less of a risk to you and your baby.

Paracetamol is usually the first line painkiller medication especially in pregnant women

During Breastfeeding

Naproxen is not recommended during breastfeeding, other NSAID's such as Ibuprofen are usually a safer option for breastfeeding women. If your baby was born premature or with any difficulties, please speak to your doctor about what other options you have before taking any pain relief medication.

Naproxen Drug Interactions

If you are taking any other medications, it is possible that these may affect the way Naproxen works.

Please inform your doctor if you are taking any other medications. The most common medications that can interact with the effectiveness of naproxen are:

  • Any other NSAID's such as Ibuprofen and Aspirin
  • Medicines that are used to thin the blood
  • Some steroids such as prednisolone used to treat allergies
  • Diuretics such as furosemide
  • High blood pressure medication and other drugs relating to heart conditions
  • Antidepressants
  • Methotrexate used to treat rheumatoid arthritis

Please tell your pharmacist or Doctor if you are taking any other forms of medications, either prescription or over the counter medicines. This also includes any vitamins or supplements.

Naproxen and Alcohol Warnings

There is no known interactions with Alcohol and Naproxen, it is generally safe to drink alcohol whilst you are taking Naproxen. However please be aware that drinking too much alcohol may irritate your stomach whilst you are tkaing Naproxen.

Naproxen FAQ's

Is Naproxen available over the counter in the UK?

Naproxen is a prescription only medicine meaning that it is not available to purchase over the counter in the UK. In order to buy naproxen medication a valid UK prescription is needed before a pharmacy will dispense the medication.

Do I need a prescription for Naproxen in the UK?

Yes, you need a valid UK prescription in order to buy naproxen. Naproxen is classed as a “POM” which means prescription only medicine. You cna purchase Naproxen from Medicine Direct Online Pharmacy

How long does Naproxen take to work?

Naproxen is a fairly fast acting medication. Typically most people will start to feel better after 1 hour of taking naproxen. When treating chronic conditions such as rheumatoid arthritis, naproxen may take up to 3 days to work properly. Naproxen is more effective if taken exactly as prescribed by a doctor or pharmacist.

Is Naproxen stronger than Ibuprofen?

When compared to Ibuprofen, naproxen is much better suited when used to treat acute pain due to its anti-inflammatory properties. Naproxen is also a long acting drug, meaning that you will tend to feel the effects for a longer period of time. Ibuprofen on the other hand is a short acting drug, which means the effects wear off quicker. As a result, Ibuprofen needs to be taken every 4 – 6 hours compared to naproxen which should be taken just twice daily.

Can I stop taking Naproxen suddenly?

You should take naproxen exactly as prescribed by your doctor. Even if your condition seems to completely clear up whilst taking naproxen, it is important to complete your full course to experience its full effects. If you suddenly stop taking Naproxen, this may cause your condition too suddenly flare up and you may experience more pain and discomfort.

Is there an alternative to Naproxen?

Most NSAID’S (Non-Steroidal Anti-Inflammatory Drugs) are similar to naproxen in the way that they all possess anti-inflammatory properties. Other NSAID’s include Ibuprofen and Celebrex. The most like for like alternative to Naproxen is Aceclofenac.

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