Amlodipine

  • Highly effective in treating high blood pressure
  • Relaxes the blood vessels and allows blood to flow through more freely
  • Can lower the risk of suffering a heart attack, stroke or developing heart disease
From As low as £12.99
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What is Amlodipine?

Amlodipine works by relaxing the blood vessels allowing blood to pass through the body more freely. It lowers your blood pressure by widening your blood vessels, which allows blood to be pumped around your body much easier. You may also recognise Amlodipine by its brand names of Istin and Amlostin.

This medication is highly effective in treating high blood pressure and coronary artery disease. These tablets are angioselective calcium channel blockers, which inhibit the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. By doing so, they allow for an increase in blood flow around your heart and a decrease in pressure.

What is Amlodipine used for?

Amlodipine tablets are prescribed to treat high blood pressure and angina. By reducing our blood pressure level, we can prevent your chances of suffering from more serious complications such as strokes, heart attacks or heart disease.

Although it is not generally used to treat heart disease, it can be prescribed to prevent the chest pain this disease causes.

Amlodipine is only available on prescription and comes available as either a liquid or tablets.

Who can take Amlodipine?

Amlodipine is a prescription-only medicine. It can be prescribed to adults and children who are aged 6 years and over.

You should not take Amlodipine if you are trying to get pregnant or are already pregnant. If you suffer from kidney or liver problems, you should talk to your doctor before being prescribed the medication.

It is not known if Amlodipine is harmful to use while breastfeeding. Although small amounts of the medication will get into the breast milk, it is not known if it is enough to harm the baby.

If your baby was born premature or with any difficulties, please speak to your doctor about what other options you have before taking any high blood pressure medication.

You should avoid eating grapefruit products and drinking grapefruit juice while taking your course of Amlodipine as it can increase the concentration of the medicine in your blood, increasing the risk of you suffering worse side effects.

Check with your doctor if this medicine is safe for you if any of the below apply:

  • You have liver or kidney disease
  • You have had an allergic reaction to Amlodipine or any other medicines in the past
  • You are trying to get pregnant or are breastfeeding

It is possible to drink alcohol while taking Amlodipine. However, it may be counterproductive or cause negative effects to drink while taking the medicine. This is because alcohol can increase blood pressure which will lower the benefits and effect of the drug. By lowering the blood pressure, this can in turn cause you to have a headache, feel dizzy or tired. You should stop drinking alcohol while taking your course of Amlodipine if this happens to you.

Other Warnings

  • You are advised not to consume grapefruit juice while taking this medication.
  • Do not take this medication is you have hypotension (severe low blood pressure).
  • Do not use this medication if you suffer from aortic stenosis or cardiogenic shock.
  • Do not take this medication if you suffer from heart failure after a heart attack.

Possible Side Effects

All medicines come with the danger of side effects. It is rare to experience any side effects while taking a medicine, but you should be aware of any possible signs that you may be reacting to the medicine.

If you are worried about symptoms you have begun to exhibit you must contact your doctor for advice. If your symptoms are more severe, seek immediate medical help.

Common side effects of taking this medicine include:

  • Headache
  • Feeling dizzy
  • Increase in temperature or flushing of face
  • Heartbeat feeling more noticeable or pounding
  • Ankles swelling

Please note, this list is not exhaustive. For a list of more serious adverse effects which are associated with this medicine, please refer to the Side Effects tab on this page.

Will Amlodipine affect my sex life?

In comparison to other blood pressure medicines, calcium channel blockers seem to cause fewer problems with people's sex lives. However, they may lead to:

  • Problems with ejaculation
  • Decreased desire to have sex in men and women
  • Decreased erection
  • Impotence (Erectile Dysfunction)
  • It should also be noted that Amlodipine can reduce fertility in men.

Non-prescription alternatives for High Blood Pressure– Lifestyle Changes

You can lower your blood pressure by leading a healthier lifestyle, which will help to prevent you developing high blood pressure and heart disease.

  • Get plenty of rest and sleep
  • Cut down on alcohol consumption
  • Do regularly exercise
  • Stop smoking
  • Cat down on caffeinated drinks
  • Cut down salt intake
  • Eat plenty fruit and vegetables

Amlodipine Dosage

You can buy Amlodipine in 2.5mg, 5mg and 10mg strengths. Here at Medicine Direct, we sell the two most common strengths your doctor may prescribe, which are 5mg and 10mg; these are available as tablets.

Usually, these tablets are taken once a day, orally, with a glass of water. While you can take it at any time during the day, it helps to take it at the same time every day. Please, follow the directions your doctor has given you.

You can take the tablet before or after eating. Make sure you swallow the medicine whole.

Amlodipine 5mg

5mg of Amlodipine is frequently used as the initial dose by patients. Your doctor may adjust this dose after reviewing your symptoms and deciding on whether you have made an improvement or not.

Amlodipine 10mg

10mg is required by most patients with angina. Your dosage may be increased to this strength if the lower dose was not effective in treating your symptoms.

Do not double dose Amlodipine to make up for forgotten doses. If you miss a dose, take it as soon as you remember. However, if you do not remember until you are close to taking your next scheduled pill, then skip the dose and continue your course as normal.

Below are the guidelines for taking Amlodipine in accordance with different conditions.

Please note that these are just the general guidelines to taking the medicine, you should always follow your doctor's instructions as your specific needs may require different dosages than the below states:

  • High Blood Pressure (Hypertension)

You will initially be prescribed 5mg to take once a day. You will usually then be given a maintenance dose of 5-10mg to continue keeping your blood pressure down. For smaller patients or those who are more fragile, you may be started on the lowest dose of 2.5mg.

  • Angina

Doctors will usually prescribe those who suffer with angina either 5mg or 10mg doses of Amlodipine. This should be taken once a day. 10mg will be the maximum dose given.

How can I tell if Amlodipine is working?

If your doctor has prescribed you Amlodipine to treat high blood pressure, you may not exhibit any physical symptoms at all. Therefore, you may not feel any different when you use this medicine. This does not mean the medicine isn't working.

If you are using it to treat chest pains, these pains should cease and you should be able to exercise without any problems.

Amlodipine FAQ's

How quickly does Amlodipine work?

This medicine begins to work as soon as you start taking it. However, it may be a couple of weeks before the tablets are completely effective and give you a normal blood pressure reading.

Can Amlodipine tablets be crushed or split?

Amlodipine tablets should be swallowed whole with a glass of water. Do not crush or chew them.

Can Amlodipine affect my contraception?

Amlodipine can interact with a range of other medicines. You should always inform your doctor of any medicine you are already using before you start taking Amlodipine, whether it is prescribed or not.

Can Amlodipine be taken alongside Paracetamol?

If you need a painkiller, Paracetamol is okay to use with Amlodipine.

Can Amlodipine be used for Raynaud's Syndrome?

Amlodipine can be prescribed to treat Raynaud's. You should speak to your doctor about this.

How do I cope with Amlodipine side effects?

Speak to your doctor about the possible adverse effects of this medicine. If you experience severe side effects, you should seek medical attention immediately.

Amlodipine vs other Calcium Channel Blockers:

Amlodipine is associated with lower blood pressure variability than other CCBs.

Is Amlodipine a statin?

No, Amlodipine is a calcium channel blocker, designed to to widen your blood vessels.

Can I drive while taking Amlodipine?

While this drug does not directly impair your ability to drive, it can sometimes make people feel dizzy or tired. If you experience this, you should not drive or operate machinery.

Is Amlodipine a cure?

This medicine controls high blood pressure, angina and coronary artery disease, but it does not cure them.

How can you make Amlodipine work faster?

This drug starts to work immediately, but it should not be taken more than you are prescribed. You can improve your health by leading an active lifestyle and eating healthily.

Will I need Amlodipine for the rest of my life?

If you are being treated for high blood pressure, you may need this medicine for the rest of your life.

Can I stop taking it if my blood pressure is lower?

If you stop taking this medicine, even if your blood pressure is lowered, this might cause it to rise again.

How do I store Amlodipine?

Store it at room temperature and keep out of direct sunlight. Keep out of reach of children.

Is Amlodipine related to any cancer risks?

Studies have shown that this drug does not increase your risk of cancer.

Is it addictive?

There is no evidence to show these tablets are addictive.

Can I take it for migraines?

This drug has been used for migraines, but you should always consult your doctor as there are many other migraine treatments available.

Can I take it for anxiety?

This drug is primarily prescribed for Hypertension (high blood pressure) by widening the blood vessels and is not generally used to treat anxiety. If you suffer from anxiety, you should contact your doctor, who will discuss all the medicines and alternative treatments available to help you with your condition.

How can I by Amlodipine online safely?

You can buy Amlodipine online when it is with a registered pharmacy, such as Medicine Direct. One of our certified doctors will prescribe the correct dose for you after a thorough consultation. You should never purchase this medicine without a valid prescription from a medical professional.

Amlodipine Serious Side Effects

In rare cases, you may experience a serious side effect from taking this medication. Some of the more serious adverse effects include:

  • Severe stomach pain
  • Bloody diarrhoea
  • Nausea
  • Vomiting (this and the above can be a sign of pancreatitis)
  • Yellowing of your skin or eyes
  • Increase or new chest pain (have this looked at as soon as possible as this may be a sign of a heart attack)

If you experience any of these side effects, you should speak to your doctor as soon as possible.

Please note that this list is not exhaustive. For a more extensive list please see the leaflet inside the medication box.

In rare cases, patients taking Amlodipine can suffer from a severe allergic reaction to the medicine.

If you experience any of the warning symptoms you MUST contact an emergency service such as 111 or 999 immediately. The signs of a severe allergic reaction are:

  • Developing a skin rash which is itchy, red, swollen, blistered or peeling
  • Your chest or throat feeling tight. This can also be displayed through wheezing.
  • Experiencing difficulty in breathing or talking
  • Your facial extremities become swollen i.e. you mouth, face, lips, tongue or throat.

Amlodipine Warnings and drug interactions

You must tell your doctor of all other medicines you are currently taking before being prescribed Amlodipine, as some medicines can interact negatively with it. Below are some of the medicines which are known to negatively affect your body while you take Amlodipine:

  • Some Antibiotics
  • Other medicines used to treat high blood pressure
  • Antifungal treatments
  • Medication used to treat HIV or HCV
  • Anti-epilepsy medicine
  • Medicine which suppresses your immune system
  • Some cholesterol-lowering medicine such as simvastatin if you take more than 20mg a day.

Taking other high blood pressure medication at the same time as Amlodipine could cause your blood pressure to lower too much and cause you to suffer from low blood pressure.

In addition to this, other medications unrelated to high blood pressure that may cause low blood pressure as a side effect should not be taken.

These include:

  • Ketoconazole
  • Itraconazole
  • Medications to treat HIV
  • Antibiotics such as rifampicin, erythromycin, clarithromycin
  • ST John’s wort
  • Verapamil
  • Diltiazem
  • Dantrolene
  • Tacrolimus
  • Simvastatin
  • Cyclosporine

Condition Interactions

  • Recent heart attack
  • Heart failure
  • Liver disease
  • You are elderly
  • Severe increase in blood pressure

Amlodipine Ingredients

The active ingredient in this medicine is Amlodipine (as amlodipine besilate).

Inactive ingredients are: Cellulose microcrystalline, Sodium starch glycolate (Type A), Silica colloidal anhydrous, Magnesium stearate.

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Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

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This content has been written by James Nuttall and has been medically reviewed by our Superintendent Pharmacist Hussain Abdeh.

Superintendent pharmacist Hussain Abdeh at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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