Desloratadine 5mg

  • Non-drowsy antihistamine medicine
  • Relieves allergic symtoms
  • Treats allergies such as Hay fever

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Desloratadine 5mg allergy relief tablets

Allergies can be triggered by a number of things, from pollen and pets to dust and food. Desloratidine 5mg allergy relief tablets can help to reduce the symptoms of allergies. Desloratadine is fast acting and can provide relief from allergy symptoms for 24 hours.

You can buy desloratadine 5mg tablets online from Medicine Direct following an online consultation with one of our UK prescribers.

What is Desloratadine?

Desloratadine is a prescription-only medicine (POM) used to treat the symptoms of allergic rhinitis, which is a condition caused by an allergy such as hay fever or dust mites. This causes inflammation of the nasal passages.

Desloratadine is a non-drowsy antihistamine medicine that effectively relieves the symptoms of allergic rhinitis by blocking your histamine receptors. It is suitable for adults and children over the age of 12 years old.

What is Desloratadine used to treat?

Desloratadine is a fast-acting antihistamine medicine that works to relieve unpleasant symptoms caused by allergic rhinitis and other allergic conditions. 

Some of the main symptoms of allergic rhinitis include:

  • Itchy or watery eyes
  • Sneezing
  • Skin rash
  • Blocked or runny nose

These tablets can also be prescribed to relieve the symptoms of urticaria, which is a skin condition caused by an allergy. The symptoms of this problem include hives and itching.

How does Desloratadine work?

Desloratadine works to block the release of a naturally occurring chemical in the body called histamine.

Your body will normally release histamine when it detects something harmful like an infection. In most cases, histamine is a beneficial substance to the body; it makes the blood vessels expand and causes the skin to swell, which helps your body to fight off harmful infections and illnesses.

However, if you are allergic to substances like pollen or animal fur, your body mistakes these substances for a threat and creates histamine. This causes an allergic reaction and brings on allergy symptoms. By blocking the release of histamine, these symptoms are avoided or reduced.

Does Desloratadine make you sleepy?

Desloratadine is a non-drowsy antihistamine medication, meaning it does not cause drowsiness.

How to take Desloratadine

Swallow Desloratadine tablets whole with a drink of water. Do not crush or chew them.

Take one 5mg tablet at around the same time each day. For the most effective defence against your allergies, take Desloratadine every day. If you miss a dose, do not take a double dose to make up for it.

Who can take Desloratadine?

Desloratadine is not suitable for everyone to use.

Do not take these tablets if you are allergic to desloratadine or any of the other ingredients contained in this medicine (please refer to the Ingredients tab for full information).

Speak to your doctor or pharmacist before taking Desloratadine if any of the below apply to you:

  • You have a medical or family history of seizures (fits)
  • You have a poor kidney function
  • You are pregnant or breastfeeding

This medicine should not be taken by anyone who has not been prescribed it. This medication is not suitable for children under the age of 12 years old.

This information is not exhaustive. Always read the patient information leaflet, which will come with your medicine, for full details on precautions.

Can you buy Desloratadine over the counter?

No, Desloratadine 5mg is not available to buy over the counter. You must be prescribed this medicine by a doctor.

Can you buy Desloratadine online in the UK?

Yes, you can buy Desloratadine from Medicine Direct’s online pharmacy. This is a prescription-only medicine (POM), so you will first need to complete an online consultation. You can do this by filling out our online questionnaire for a registered doctor or pharmacist to review. This is to make sure that Desloratadine is an appropriate medicine for you and your specific condition.

Order by 2pm and you will receive your medicine the next day.

For your own safety, you should never order any type of medication online unless it is from a fully regulated UK pharmacy, like Medicine Direct.

Desloratadine alternatives

Unfortunately, you cannot cure allergies like allergic rhinitis. Nonetheless, with the right medication you can control your symptoms and lead a full and active life, unhindered by your condition. Fortunately, there are many different medicines available to treat this problem.

At Medicine Direct, we have several effective antihistamine medicines for sale. Other antihistamines we stock include Loratadine, Levocetirizine and Cetirizine, which is also available as a liquid solution. These medicines will work in the same way as Desloratadine to provide comprehensive relief from your symptoms.

Corticosteroid nasal sprays like Flixonase and Rhinolast can also be ordered. Corticosteroids work by reducing inflammation in the nose, which helps to stop excessive mucus production. By doing this, the other symptoms of allergic rhinitis will also be relieved.

To see our full range of treatments, visit the Hay Fever page on our website.

You can also try non-medicinal tactics to reduce your risk of being bothered by allergies, including:

  • Not going outside on days with high pollen counts, we recommend checking the UK pollen forecast on a daily basis.
  • Wearing a scarf around your mouth and wrap-around sunglasses on days when you do need to go out
  • Showering when you come home to wash off any allergy particles you may have picked up
  • Using a pollen filter in your car
  • Closing windows at home on days with high pollen counts
  • Hoovering and dusting regularly

Desloratidine Indications and Dose

Our pharmacists and prescribers follow NICE guidelines when prescribing Desloratadine tablets.

Adults and children over 12 years old

The recommended dose is one tablet once a day, which can be taken with or without food.

Desloratadine tablets should be swallowed whole with a drink of water.

This medicine is for oral use only.

How long does it take to work?

Desloratadine is a fast-acting antihistamine. How long you will need to take it will depend on the type of allergic rhinitis you have; your doctor will advise you as to how long you should take Desloratadine.

If you have allergic rhinitis that lasts for less than four weeks, or is intermittent, your doctor will recommend an appropriate treatment schedule for your specific condition.

If you the problem continues for longer than four weeks, a longer treatment plan may be advised.

If you are suffering from urticaria, you should follow your doctor's instructions as treatment lengths for this condition can often vary from person to person.

What if I forget to take it?

If you forget to take a dose of Desloratadine, take it as soon as you remember, then continue taking it as normal. If you only remember to take it close to your next scheduled dose, just skip the dose you missed and take Desloratadine as usual.

Do not take more than one tablet a day unless instructed to do so by a doctor.

Do not take a double dose to try and make up for missing an earlier one.

What if I take more than I am supposed to?

Only take Desloratadine as instructed by your doctor. Taking an extra dose is unlikely to do you any harm, but you should contact your doctor or pharmacist immediately if you do take more of this medicine than you were instructed to.

How strong is Desloratadine?


Desloratadine is a prescription-strength antihistamine.

How long does Desloratadine take to work?


You should notice Desloratadine getting to work within one hour of taking the medicine. The effects last for up to 24 hours.

Do Desloratadine tablets make you tired?


Drowsiness is a very rare side effect, affecting up to 1 in 10,000 people. If this affects you, do not drive, cycle or use machines until you feel better. Tell your doctor if this side effect does not go away.

How long can you take Desloratadine?


Your doctor will advise you as to how long you should take Desloratadine for. Ask your doctor or pharmacist if you are not sure.

Does Desloratadine affect blood pressure?


Desloratadine is not commonly associated with affecting high or low blood pressure. If you go for a blood pressure test, tell your doctor or nurse that you are taking this medication.

Can I take Desloratadine with other antihistamines?


You should not take more than one antihistamine at the same time unless your doctor tells you to.

What is the difference between Desloratadine and Loratadine?


Both of these medicines are non-drowsy antihistamines and can be used for effective hay fever treatment. Loratadine is available to buy over the counter, whereas Desloratadine is prescription-only. Loratadine’s recommended dose is normally 10mg, and it is usually cheaper to buy this medication.

Can I drink alcohol with Desloratadine?


You are advised to not drink alcohol while taking antihistamines, as this may cause drowsiness. Desloratadine is a non-drowsy antihistamine, but it may still cause drowsiness.

Will Desloratadine affect my contraception?


Desloratadine will not affect contraception, including emergency contraception and combined oral contraceptive pills.

Is it safe to take Desloratadine every day?


Yes, you should take Desloratadine at the same time each day. Your doctor will tell you how long to take it for.

Desloratidine Side effects

Like all medicines, Desloratadine comes with the risk of certain side effects, although these will not bother everyone who takes it.

Common adverse effects may include:

  • Dry mouth
  • Fatigue
  • Headache

The following side effects may occur in an unknown frequency:

  • Weight gain
  • Increased appetite
  • Yellowing of the skin or eyes
  • Increased skin sensitivity to the sun
  • Abnormal behaviour
  • Aggression
  • Changes in your heartbeat
  • Unusual weakness

Speak to your doctor or pharmacist if you suffer from any of the reactions listed above.

Please note, this list is not exhaustive. Please refer to the Side Effects tab for information on rarer and more serious reactions.

Serious Side Effects

Children may suffer from the following side effects:

  • Slow heartbeat
  • Aggression
  • Abnormal behaviour
  • Changes in how the heart beats

Rare side effects can include:

  • Fast heartbeat
  • Stomach aches
  • Seizures
  • Hallucinations
  • Sleeping problems
  • Dizziness
  • Diarrhoea
  • Drowsiness
  • Vomiting
  • Feeling sick or being sick
  • Muscle pain
  • Upset stomach
  • Abnormal liver function test results
  • Inflammation of the liver
  • Feeling restless with increased body movement
  • Rash

Seek medical attention if any of the above side effects bother you.

Severe allergic reaction

In rare cases, it is possible to suffer a serious allergic reaction to Desloratadine.

Go to A&E or call 999 straight away if:

  • You are wheezing
  • You develop a skin rash that may have red, swollen, itchy, blistered or peeling skin
  • You have tightness in your chest or throat
  • You have swelling in your face, mouth, tongue, lips or throat
  • You are finding it difficult to breathe or speak

You may require immediate treatment in hospital.

Always read the patient information leaflet for comprehensive details on side effects. If you have any concerns, please discuss these with your doctor.

Warnings and Drug Interactions

Before taking Desloratadine, inform your doctor or pharmacist if you are currently taking any other medication. This includes prescribed and non-prescribed medication, vitamins, herbal remedies or supplements. There are some known interactions of Desloratadine with other medication.

Desloratadine is a non-drowsy antihistamine. However, in rare cases it can cause drowsiness; if this does happen, you are advised to not drive, operate machinery or cycle until this effect has worn off.

Do not give this medicine as a treatment for hay fever or any other condition to children un 12 years old.

Always read the patient information pamphlet thoroughly before you start taking Desloratadine. If you have any questions or concerns, we strongly advise you to discuss these with your doctor.

Pregnancy and breastfeeding

Desloratidine use in pregnancy is not known to cause any major birth defects when compared to other antihistamines that are commonly used during pregnancy such as Loratadine.

Speak to your doctor or pharmacist for guidance before using this medicine if you are currently pregnant, think you might be pregnant, are trying to get pregnant, or are breastfeeding.

Desloratadine Ingredients

The main active ingredient within this medicine is: Desloratadine

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

This page has recently been medically reviewed by Hussain Abdeh MPharm: 2211840

Updated on: 28/07/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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