Prochlorperazine 3mg Buccal Tablets

  • Used to treat Nausea and Sickness
  • 'Buccal' tablets dissolve in your mouth
  • Fast dissolving and quick acting

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Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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What are Prochlorperazine 3mg Buccal Tablets?

maximum quantity per treatment - 50 tablets

Prochlorperazine is an anti-sickness medicine that is taken to prevent nausea and vomiting. It contains the active ingredient prochlorperazine maleate and can be taken to treat the likes of morning sickness and vertigo.

These buccal tablets are ideal for people who have trouble swallowing medicine. You simply place them under your upper lip and allow them to dissolve in your mouth.

Prochlorperazine is also available as the generic Prochlorperazine 5mg tablets and as a branded version, Stemetil (Prochlorperazine) 5mg tablets.

What are Prochlorperazine 3mg buccal tablets used to treat?

Prochlorperazine 3mg buccal tablets are an effective medicine for treating nausea and vomiting.

You can use Prochlorperazine 3mg buccal tablets to treat nausea that comes with a variety of different conditions, including:

  • Morning sickness
  • Travel sickness
  • Migraines
  • Vertigo (dizziness)
  • Conditions that affect balance
  • Sickness that comes from cancer treatments, general anaesthetics or from taking other medicines

In some cases, Prochlorperazine may also be prescribed to treat anxiety.

How does Prochlorperazine work?

The active ingredient contained in Prochlorperazine 3mg buccal tablets is prochlorperazine maleate, which belongs to a group of medicines known as phenothiazines. Prochlorperazine maleate works by blocking the dopamine receptors in the section of the brain that causes nausea. This prevents nausea messages from being sent to the “vomiting centre” in your brain, helping to stop you feeling sick.

Typically, Prochlorperazine 3mg buccal tablets will start to work in around 30 to 60 minutes. Buccal tablets are most effective if you take them after meals, as this gives them more time to dissolve.

How to take Prochlorperazine Buccal Tablets

The recommended dose for adults and children over 12 years old is one or two tablets twice a day.

  1. Place the tablet high along the top gum under your top lip.
  2. The tablet will adhere to the gum and dissolve. Allow it to dissolve completely, which may take 1–2 hours; most people stop noticing the tablet after a few minutes.
  3. Do not move the tablet around your mouth with your tongue as this can cause it to dissolve too quickly.

Do not chew or swallow the tablet.

If you wear dentures, you can place the tablet anywhere that is comfortable between your lip and gum.

It is best if you take Prochlorperazine buccal tablets after meals.

Always read the patient information leaflet that comes with your medicine for full instructions.

Who can take Prochlorperazine Buccal Tablets?

Prochlorperazine provides effective relief from nausea and vomiting, but it may not be suitable for everyone to use.

Comprehensive information on who this medicine may not be suitable for can be found in the patient information leaflet.

Do not take Prochlorperazine tablets if any of the following apply to you:

  • You are allergic to prochlorperazine maleate or any of the other ingredients contained in this medicine
  • You have any prostate gland problems
  • You have any liver problems
  • You have any blood problems
  • You have epilepsy, Parkinson’s disease or glaucoma

Talk to your doctor before taking Prochlorperazine 3mg buccal tablets:

  • If you are elderly
  • If you are currently pregnant, trying to get pregnant, think you might be pregnant or are breastfeeding
  • If you have AIDS
  • If you suffer from myasthenia gravis, a condition which causes muscle weakness
  • If you are at risk of a stroke or blood clot, such as diabetes, high cholesterol levels, high blood pressure, or you smoke
  • If you or anyone in your family has a history of blood clots

Pregnancy and breastfeeding

If you are pregnant, you should only take this medicine if your doctor has prescribed it for you.

When a pregnant woman takes this medicine in the final three months of pregnancy, a newborn baby may experience the following:

  • Muscle stiffness/weakness
  • Agitation
  • Difficulty feeding
  • Breathing problems
  • Shaking

Speak to your doctor if your baby develops any of these issues.

You should not take these tablets while breastfeeding as there is not enough research to prove that it is safe to do so. Learn more about taking prochlorperazine when pregnant and breastfeeding.

Can you buy Prochlorperazine Buccal Tablets over the counter?

Prochlorperazine buccal tablets are a prescription-only medicine (POM).

Can you buy Prochlorperazine Buccal Tablets online in the UK?

To buy Prochlorperazine buccal tablets online from Medicine Direct, you will first need to fill out an online form. This will ask you questions about your medical history and condition; it will then be reviewed by one of our certified prescribers to make sure that Prochlorperazine is the most suitable medicine for your problem.

If you have ordered by 2pm, we can offer you next day delivery on your medication. Medicine Direct is regulated by the General Pharmaceutical Council (GPhC) and the MHRA. This ensures we sell only approved and safe medicine from our online pharmacy. For your own safety, do not order any type of medicine online from anywhere other than regulated pharmacies.

Prochlorperazine alternatives

There are several anti-sickness medications available to order from Medicine Direct. There is insufficient evidence to prove which medicine is the most effective at relieving nausea, so you might need to try a few until you find the one which best relieves your symptoms.

Prochlorperazine is also available as the branded Stemetil 5mg tablets, or as generic Prochlorperazine tablets. These medicines work in the same way as Prochlorperazine buccal tablets, but you will instead swallow the tablets whole.

Antihistamine medicine which is used to treat nausea such as Cyclizine 50mg tablets and Dopamine Agonists such as Domperidone are also renowned anti-sickness medicines. These tablets will also work to block the messages being sent to the vomiting centre in the brain and get to work after around half an hour.

Prochlorperazine 3mg Buccal Tablets Dosage and Directions

How to take Prochlorperazine 3mg Buccal tablets

Our pharmacists and prescribers follow NICE guidelines when prescribing Prochlorperazine Buccal Tablets.

Always take Prochlorperazine tablets exactly as instructed by your doctor or pharmacist. Read the patient information leaflet thoroughly and ask your doctor or pharmacist if you are not sure.

If you take more than you were supposed to

An overdose of Prochlorperazine can be dangerous. Call 111 or speak to your doctor straight away if you have taken too much.

How to store Prochlorperazine Tablets

Store this medicine out of the sight and reach of children.

Keep out of direct sunlight; store the tablets in the original carton.

These tablets do not require any special storage conditions, but do not continue to use the medicine after the expiry date, which can be found on the packaging. The expiry date refers to the last day of the month stated.

What happens if you swallow buccal tablets?


Swallowing a buccal tablet like Prochlorperazine means that it will not work. You should make sure it is left to dissolve in the top of your mouth.

How long does it take to work?


Prochlorperazine should start to work after around 30 to 60 minutes. For most effective results, take the tablets after a meal.

Can I take it for a long time?


You can take Prochlorperazine in the long term if required, but this should only be on your doctor’s recommendation.

Can I drink alcohol with it?


You should not drink alcohol while taking any prochlorperazine medicines as this can exacerbate certain side effects.

Can Prochlorperazine cause depression?


This medicine can cause depression in some people or make existing depression symptoms worse. Speak to your doctor before using this medicine if you are suffering from depression or taking any medication to treat depression.

Can you take Prochlorperazine for anxiety?


Yes, Prochlorperazine is sometimes prescribed as a short-term treatment for anxiety. Your doctor will advise you if they believe this medicine may help you with this problem.

Will it affect my fertility?


Prochlorperazine can raise the levels of a hormone called prolactin. High levels of prolactin can cause impotence in men and stop periods in women, although this is not normally a side effect when taking prochlorperazine in the short term.

Is Prochlorperazine addictive?


This medicine does not normally cause addiction, but if you stop taking it suddenly after using it for a long period, you may experience withdrawal symptoms like nausea or sleep problems. If you have been taking Prochlorperazine for a long time and wish to stop taking it, speak to your doctor about how to gradually reduce your dose.

Will Prochlorperazine make you high?


If abused like more common drugs, Prochlorperazine is not known to cause euphoria. However, it can still have mood and perception-altering effects. Never take more than the prescribed dose of any medicine. Taking a large dose of Prochlorperazine can be fatal.

Are there other anti-sickness medicines?


Yes, there are other anti-sickness medicines, including Domperidone and Cyclizine which are available from our online pharmacy. There is not enough evidence to say which is the most effective at helping with nausea symptoms. You may need to try more than one anti-sickness medicine to find the best one for you.

Prochlorperazine Buccal Tablets Side Effects

Rare side effects of Prochlorperazine include:

  • Jaundice
  • Blood problems
  • Breast swelling (in men and women)
  • Milk secretion from the breast which is not a result of breastfeeding
  • Feeling anxious or restless
  • Women not getting their monthly period

Contact your doctor right away if you suffer from any of the below:

  • Convulsions
  • Symptoms of an infection (shivering, high temperature, sweating, headache, swollen glands or sore throat)
  • Blood clots
  • Symptoms of decreased sodium concentration in the blood (headache, nausea and vomiting, cramps, seizures, coma)
  • Symptoms of a serious allergic reaction (please see below)
  • Symptoms of neuroleptic malignant syndrome (pale complexion, high temperature, alertness levels change, muscle stiffness)

Serious allergic reaction

If you notice any of the following symptoms, you must call 999 or go to A&E straight away.

You might be having a serious allergic reaction and need immediate treatment in hospital if:

  • You have swelling in your mouth, face, lips, tongue or throat
  • You are wheezing
  • You are finding it difficult to breathe or speak
  • You have tightness in your throat or chest
  • You develop a skin rash that may include red, itchy, swollen, blistered or peeling skin

Always read the patient information leaflet for full details on side effects and how you should deal with them. If you are worried about getting side effects or have any questions, we strongly advise you to discuss your concerns with your doctor or pharmacist before you start taking Prochlorperazine.

ProchlorperazineBuccal Tablets Warnings

Avoid exposure to direct sunlight and use sunscreen while taking Prochlorperazine, as this medicine may make you more sensitive to sunlight.

Read the patient information leaflet for a full list of warnings and drug interactions before you start taking this medicine. If you have any questions or concerns, please speak to your doctor or pharmacist.

Other medicines and Prochlorperazine tablets

Before you start to take Prochlorperazine buccal tablets, please inform your doctor or pharmacist of any other medicines you are already using. This includes both prescription and non-prescription medicine, herbal remedies, vitamins and supplements.

It is particularly important that they are aware if you are currently taking, or have recently taken, any of the following medications:

  • Desferrioxamine (for high levels of iron in the body)
  • Lithium (for mania and depression)
  • Any sedatives or tranquilisers to help you to sleep
  • Any antihypertensive medicines for high blood pressure
  • Any anticholinergic medicines (normally used for depression)
  • Any anticonvulsant medicines (to treat or prevent fits)

For more information on medicines that interact with Prochlorperazine Buccal Tablets.

Prochlorperazine Tablets with food and drink

Ideally, you should take Prochlorperazine after a meal.

Do not drink alcohol while using Prochlorperazine as it may interact with this medicine.

Driving and using machines

Prochlorperazine 3mg buccal tablets may cause side effects like dizziness, drowsiness and convulsions.

Do not drive, cycle or operate any machinery if you experience any of these reactions while taking this medication. If these symptoms continue, please contact your doctor or pharmacist for advice.

Prochlorperazine tablets contain sucrose

Speak to your doctor or pharmacist before using this medication if your doctor has previously told you that you are intolerant to certain sugars.

Prochlorperazine 3mg Buccal Ingredients

The main active ingredient within this medicine is: Prochlorperazine maleate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Written byHussain Abdeh MPharm: 2211840

Updated on: 17/05/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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