Seretide Inhaler

  • Combination Inhaler
  • Reduces inflammation of the lungs and airways
  • Prevents future Asthma attacks
  • Provides effective relief for up to 12 hours
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From As low as £32.99

Disclaimer: The prices displayed should only be used as a reference of our prices for this medicine. If you are approved for treatment, our prescribers will decide on a suitable treatment for you to jointly consider.

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What is Seretide?

Seretide is a long-acting beta2-agonist bronchodilator (LABA) which helps the airways in the lungs to stay open. It contains two active ingredients, salmeterol, and fluticasone propionate, it is classed as a steroid inhaler.

Seretide is an inhaler that makes it easier for air to go in and out of your lungs. The effects of this inhaler last for 12 hours at a time.

Seretide is a type of combination inhaler which contains both the characteristics of a brown preventer inhaler and a blue reliever inhaler. A combination inhaler is essentially a preventer and reliever inhaler in one.

It comes available either as the Accuhaler or Evohaler; both contain the same medicine, but the way they release the medicine differs.

What is Seretide used to treat?

Seretide is used to treat patients who suffer from moderate to severe asthma. The medicines contained within Seretide reduce inflammation of the lungs and can help prevent future asthma attacks.

The Seretide inhaler is effective in helping to stop wheezing and breathlessness from coming on. It can be used to help prevent asthma attacks and is commonly used in the treatment of asthma, COPD and the prevention of exercise induced bronchospasm. It is usually used in the treatment of persistent asthma.

How does Seretide inhaler work?

The salmeterol ingredient within seretide is a long-acting beta-2 adrenergic, when inhaled into the lungs it helps to supress cell mediators such as histamine and prostaglandins that contribute to inflammation. By supressing histamine and prostaglandin, inflammation is also reduced.

A single inhaled dose of Salmeterol lasts for approximately 12 hours.

Fluticasone propionate is a corticosteroid and is used to help manage asthma symptoms by reducing inflammation in the airways. Fluticasone also directly increases the beta-2 receptors in the smooth muscle of the airways. When the beta-2 receptors are activated, this causes bronchodilation which relaxes the airways and makes breathing easier.

How to use Seretide Inhaler

Using the Seretide Accuhaler:

To treat asthma in adults and children over 12 years of age:

  • Seretide Accuhaler 50/100 - One inhalation twice a day
  • Seretide Accuhaler 50/250 - One inhalation twice a day
  • Seretide Accuhaler 50/500 - One inhalation twice a day

Using the Seretide Evohaler:

Adults and children aged 12 years and over

  • Evohaler 25/50 - 2 puffs two times a day
  • Evohaler 25/125 - 2 puffs two times a da
  • Evohaler 25/250 - 2 puffs two times a day

Who can use the Seretide inhaler?

The Seretide inhaler is a commonly prescribed inhaler to treat asthma, but it is not suitable for everyone.

If you suffer from asthma and your doctor prescribes you an inhaler, you should make sure they are aware if any of the following conditions apply to you:

  • You have an overactive thyroid gland
  • You have high blood pressure
  • You have had or currently have tuberculosis (TB) or any other lung infection
  • You have diabetes mellitus
  • You have low potassium in your blood
  • You have heart disease, including a fast heartbeat or irregular heartbeat

If you are currently pregnant, trying to get pregnant or think you might be pregnant, you should inform your doctor before you start to use the inhaler.

Similarly, you should inform your doctor before using Seretide if you are currently breastfeeding. There may be more suitable asthma inhalers available for you to use instead.

Seretide is a safe and effective asthma treatment in children.

Can you buy Seretide inhaler online?

Yes, you can buy seretide inhaler online from most UK pharmacies. You will be required to complete an online health questionnaire so your condition can be assessed by a doctor or healthcare professional to ensure the treatment is suitable for you.

It is important to always buy medicine from a fully regulated UK online pharmacy. To learn more about our licenses and regulations, visit our about us page. You will also find more information about our team and medical professionals.

Seretide Indications and Dose

You must use Seretide every day as instructed by your doctor. Do not deviate from your doctor's instructions. Always check with your doctor if you have any questions or concerns.

Depending on how well your asthma treatment goes, your doctor may alter your dosage and how often you take the inhaler.

All of our Doctor and Pharmacists will follow NICE prescribing guidelines for Seretide.

Do not stop taking the inhaler, even if you begin to feel better, before your doctor tells you it is safe to stop. You should not reduce or increase the dose your doctor has instructed you to take.

Rinse your mouth after using the Accuhaler or Evohaler to prevent the risk of thrush appearing in your mouth.

Seretide Inhaler FAQ's

Should I use my Seretide inhaler during an asthma attack?


Most combination inhalers such as seretide do not give quick enough relief in the event of an asthma attack. You should always continue to carry your blue reliever inhaler with you at all times.

What is a combination inhaler?


A combination inhaler contains both reliever and preventer medicine in one inhaler. It helps to prevent inflammation in the airways as well as provide fast relief from symptoms.

How long does it take for Seretide to work?


The reliever properties of this inhaler will start to work quickly and help to give instant relief from symptoms. The preventer properties of this medicine will start to work within 1 week.

Is seretide a steroid?


Seretide contains Fluticasone which is classed as a steroid.

How long will I need to use my inhaler for?


Most people will use Seretide for many years to come, you should carry your inhaler with you at all times. Asthma attacks can appear out of nowhere with no warning, even if you are not experiencing any symptoms.

How often should I use Seretide?


You should use your inhaler every day, typically 1 puff in the morning and evening.

Is it safe to use Seretide for a long time?


Yes, the medicine contained within this inhaler do not cause any long lasting side effects.

Seretide Side effects

As with all medicines used to prevent asthma, using Seretide does come with the risk of certain side effects.

Not everyone will experience an adverse effect from using a Seretide inhaler, but you should let your doctor know if you experience any of the following while you are using the inhaler:

  • Headaches
  • Fever or chills
  • Increased mucus production or a change in the colour of your mucus
  • Increased cough or increased breathing problems
  • Oral thrush (rinse your mouth after using the inhaler to help prevent this problem)
  • Muscle cramps
  • Aching/swollen joints or muscle pain

You should be aware that this list is not exhaustive. For a list of more serious reactions, please refer to the Side Effects tab on this product's page.

Patient information leaflet

Seretide Accuhaler patient information leaflet.

Seretide Evohaler patient information leaflet.

Adverse Side Effects

The main adverse effects of using this inhaler can be found on the main product page.

In rarer cases, some people do experience more serious side effects while using the Seretide Accuhaler or Evohaler to treat asthma.

You should speak to your doctor if you experience any of these reactions:

  • Cataract
  • Very fast heartbeat
  • Feeling shaky, a fast heartbeat or an uneven heartbeat
  • Chest pain
  • Difficulty in sleeping
  • Allergic skin reaction
  • Mood changes, such as becoming irritable
  • Fungal infections
  • Depression
  • Blurred vision

In some instances, you may experience a severe allergic reaction to Seretide. If you exhibit any of the following symptoms, you should either call 999 or go to A&E immediately:

  • Swelling of the throat, mouth, lips, tongue, or face
  • Difficulty in breathing of speaking
  • A skin rash that is itchy, red, blistering, swollen or peeling
  • You are wheezing
  • You have tightness in the chest of throat

This list may not be exhaustive. You should always read the patient information leaflet thoroughly before you start taking this medication.

If you have any concerns or questions, always speak to your doctor before taking any treatment for asthma or any other condition.

Seretide Warnings and Drug Interactions

If you use Seretide with other medicines, they may interact with each other.

You should always tell your doctor if you are currently using any medicine, whether it is for asthma symptoms or a completely different ailment. This includes both prescription and non-prescription medicines, herbal remedies, vitamins and supplements.

In particular, you should inform your doctor if you are currently using or have recently used any of the following:

  • Medicines to treat HIV
  • Medicines which contain fluticasone propionate or salmeterol
  • Beta blockers for high blood pressure or heart conditions
  • Diuretics (water tablets) to treat high blood pressure
  • Any other bronchodilators (such as salbutamol)
  • Xanthine medicines, which are often used in the treatment of asthma
  • Corticosteroids (either by mouth or injection)
  • Any medicines that are to treat infections

You should always make sure you thoroughly read the patient information leaflet before using the Accuhaler or Evohaler as this list may not be exhaustive.

You can view a full list of Seretide Drug Interactions here.

Pregnancy and breastfeeding

Seretide is considered safe to use during pregnancy and breastfeeding. 

Learn more about using Seretide during pregnancy and breastfeeding.

Seretide Ingredients

The main active ingredients within this medicine are: Fluticasone propionate and Salmeterol xinafoate

For a full list of the inactive ingredients, please read the Summary of Product Characteristics

Delivery Company Delivery Service Price Details
Royal Mail UK Delivery Standard UK Tracked £2.99 3 - 4 Working Day Delivery
DPD UK Next Day Delivery Next Day Delivery - Tracked £5.95 Order by 2pm (subject to Dr approval) Next Working Day Delivery
DPD UK Next Day Delivery Next Day Tracked Morning Delivery by 12:00pm £12.95 Next Working Day Morning Delivery by 12:00pm
DPD UK Next Day Delivery Tracked Saturday Delivery £9.95

Delivery specified for Saturday

Order Friday by 2pm (subject to Dr approval)

Please note that next day delivery to Northern Ireland, Scottish Highlands & Islands and British Isles cannot be guaranteed. Please contact our team for more information.

Medically reviewed byHussain Abdeh MPharm: 2211840

Updated on: 22/06/2021

This content has been written by our Superintendent Pharmacist Hussain Abdeh and has been medically reviewed by our Pharmacist Sonia Khan

Hussain Abdeh Superintendent Pharmacist at Medicine Direct

Hussain Abdeh
MPharm: 2211840

Pharmacist Independent Prescriber

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